The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
The natural history of egg allergy in an observational cohort
Open accessAbstract
Background There are few studies on the natural history of egg allergy and most are single site, not longitudinal, and have not identified early predictors of outcomes. Objective To describe the natural course of egg allergy and to identify early prognostic markers. Methods Children aged 3–15 months were enrolled in a multicenter observational study with either a convincing history of an immediate allergic reaction to egg and/or milk with a positive prick skin test (SPT) to the trigger food; and/or moderate-severe atopic dermatitis and a positive SPT to egg or milk. Children enrolled with a clinical history of egg allergy were followed longitudinally and resolution was established by successful ingestion. Results The egg-allergic cohort consists of 213 children followed to a median age of 74 months. Egg allergy resolved in 105 (49.3%), at a median age of 72 months. Factors that were most predictive of resolution included the following: initial reaction characteristics (isolated urticaria/angioedema vs other presentations), baseline egg-specific IgE level, egg SPT wheal size, atopic dermatitis severity, IgG4 and IL-4 response (all P<0.05). Numerous additional baseline clinical and demographic factors and laboratory assessments were not associated with resolution. Multivariate analysis identified baseline egg-specific IgE and initial reaction characteristics as strongly associated with resolution; a calculator to estimate resolution probabilities using these variables was established. Conclusions In this cohort of infants with egg allergy, about one half had resolved over 74 months of follow-up. Baseline egg-specific IgE and initial reaction characteristics were important predictors of the likelihood of resolution.
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The prevalence, severity, and distribution of childhood food allergy in the United States
Gupta, R. S., Springston, E. E., Warrier, M. R., Smith, B., Kumar, R., Pongracic, J., & Holl, J. L. (2011) · PEDIATRICS · doi:10.1542/peds.2011-0204 · Cited by 1,417
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Sampson, H. A., Gerth van Wijk, R., Bindslev-Jensen, C., Sicherer, S., Teuber, S. S., Burks, A. W., Dubois, A. E. J., Beyer, K., Eigenmann, P. A., Spergel, J. M., et al. (2012) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2012.10.017 · Cited by 744
Self-citationSicherer, S. H. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.11.044 · Cited by 722
Self-citationOral Immunotherapy for Treatment of Egg Allergy in Children
Burks, A. W., Jones, S. M., Wood, R. A., Fleischer, D. M., Sicherer, S. H., Lindblad, R. W., Stablein, D., Henning, A. K., Vickery, B. P., Liu, A. H., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1200435 · Cited by 700
Self-citationHypoallergenic Infant Formulas
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Self-citationLiu, A. H., Jaramillo, R., Sicherer, S. H., Wood, R. A., Bock, S. A., Burks, A. W., Massing, M., Cohn, R. D., & Zeldin, D. C. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.07.026 · Cited by 521
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Dramburg, S., Hilger, C., Santos, A. F., de las Vecillas, L., Aalberse, R. C., Acevedo, N., Aglas, L., Altmann, F., Arruda, K. L., Asero, R., et al. (2023) · Pediatric Allergy and Immunology · doi:10.1111/pai.13854 · Cited by 298
Food Allergy from Infancy Through Adulthood
Sicherer, S. H., Warren, C. M., Dant, C., Gupta, R. S., & Nadeau, K. C. (2020) · The Journal of Allergy and Clinical Immunology: In Practice · doi:10.1016/j.jaip.2020.02.010 · Cited by 201
Self-citationCow's Milk protein allergy as a model of food allergies
Giannetti, A., Toschi Vespasiani, G., Ricci, G., Miniaci, A., di Palmo, E., & Pession, A. (2021) · Nutrients · doi:10.3390/nu13051525 · Cited by 92
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Gawryjołek, J., Wycech, A., Smyk, A., & Krogulska, A. (2021) · Advances in Dermatology and Allergology · doi:10.5114/ada.2021.106248 · Cited by 5
Metadata
- Authors
- Sicherer, S. H., Wood, R. A., Vickery, B. P., Jones, S. M., Liu, A. H., Fleischer, D. M., Dawson, P., Mayer, L., Burks, A. W., Grishin, A., Stablein, D., & Sampson, H. A.
- Venue
- Journal of Allergy and Clinical Immunology
- Publisher
- Elsevier BV
- Published
- 2014-02
- Volume
- 133
- Issue
- 2
- Pages
- 492-499.e8
- ISSN
- 0091-6749 (ISSN-L)
- OpenAlex
- W4297068551
- Cited by
- 280
- References
- 34
- FWCI
- 19.66
- Type
- journal article
- Language
- en
- Open access
- green
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