Acute Pancreatitis is Highly Prevalent and Complications can be Fatal in Patients with Familial Chylomicronemia: Results From a Survey of Lipidologist
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Acute pancreatitis with hypertriglyceridemia carries a risk of major complications two to three times that of pancreatitis without hypertriglyceridemia.
“with an associated risk of major complications that is two or three times as high as the risk among patients with pancreatitis without hypertriglyceridemia”
From Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome (2019) · cites this paper as [29]
Acute pancreatitis carries a 6% risk of death.
“as well as an associated 6% risk of death from acute pancreatitis.26,29,30”
From Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome (2019) · cites this paper as [29]
The prevalence of acute pancreatitis in familial chylomicronemia syndrome is uncertain but may reach 67%.
“The reported prevalence of acute pancreatitis among patients with this syndrome is not known with certainty but may be as high as 67%, 29”
From Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome (2019) · cites this paper as [29]
Up to 50% or more of patients with FCS that have uncontrolled TG levels develop recurrent acute pancreatitis.
“Up to 50% or more of patients with FCS that have uncontrolled TG levels develop recurrent acute pancreatitis.53”
From Familial chylomicronemia syndrome: Bringing to life dietary recommendations throughout the life span (2018) · cites this paper as [53]
Cites
Brown, A. S., Bakker-Arkema, R. G., Yellen, L. G., et al. (1998) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(98)00300-3 · Cited by 181 · see citing works
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Gouni-Berthold, I., Alexander, V. J., Yang, Q., Hurh, E., Steinhagen-Thiessen, E., Moriarty, P. M., Hughes, S. G., Gaudet, D., Hegele, R. A., O'Dea, L. S. L., et al. (2021) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(21)00046-2 · Cited by 232 · see citing works
Self-citationFamilial chylomicronemia syndrome: Bringing to life dietary recommendations throughout the life span
Williams, L., Rhodes, K. S., Karmally, W., Welstead, L. A., Alexander, L., & Sutton, L. (2018) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2018.04.010 · Cited by 125 · see citing works
Characterizing familial chylomicronemia syndrome: baseline data of the APPROACH study
Blom, D. J., O'Dea, L., Digenio, A., Alexander, V. J., Karwatowska-Prokopczuk, E., Williams, K. R., Hemphill, L., Muñiz-Grijalvo, O., Santos, R. D., Baum, S., et al. (2018) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2018.05.013 · Cited by 82 · see citing works
Self-citationThe burden of familial chylomicronemia syndrome: Results from the global IN-FOCUS study
Davidson, M., Stevenson, M., Hsieh, A., Ahmad, Z., Roeters van Lennep, J., Crowson, C., & Witztum, J. L. (2018) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2018.04.009 · Cited by 82 · see citing works
Self-citationThe burden of familial chylomicronemia syndrome: interim results from the IN-FOCUS study
Davidson, M., Stevenson, M., Hsieh, A., Ahmad, Z., Crowson, C., & Witztum, J. L. (2017) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2017.1311786 · Cited by 54 · see citing works
Self-citation
- Authors
- Gaudet, D., Blom, D., Bruckert, E., Stroes, E., Kastelein, J., John, K., Malloy, M., Moulin, P., Retterstøļl, K., Hughes, S., Tsimikas, S., & Witztum, J.
- ORCID
- Venue
- Journal of Clinical Lipidology
- Publisher
- Elsevier BV
- Published
- 2016-05
- Volume
- 10
- Issue
- 3
- Pages
- 680-681
- ISSN
- 1876-4789 (ISSN-L)
- 1933-2874
- OpenAlex
- W2397746860
- Cited by
- 30
- References
- 1
- Citations by year
- 2025: 3 · 2024: 3 · 2023: 2 · 2022: 1 · 2021: 2 · 2020: 8 · 2019: 4 · 2018: 6 · 2017: 1
- FWCI
- 4.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of clinical lipidology (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Pancreatitis Pathology and Treatment
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
- Health Sciences › Medicine › Surgery › Lymphatic Disorders and Treatments
- Keywords
- acute pancreatitis, familial chylomicronemia, hypertriglyceridemia, familial hypertriglyceridemia, pancreatitis complications, prevalence, fatal outcome
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