Apolipoprotein B measurement: need for standardization
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Given the improvements of standardization initiated by the IFCC, measurements of apolipoproteins have the potential to meet analytical performance criteria including accuracy, harmonisation across laboratories, unambiguous definition of the measurand, and unequivocal test results in both normo- and dyslipidemic sera.
“Given the improvements of standardization initiated by the IFCC [69], measurements of apolipoproteins have the potential to meet analytical performance criteria including accuracy, harmonisation across laboratories, unambiguous definition of the measurand, and unequivocal test results in both normo-and dyslipidemic sera -important prerequisites for medical use of a test which can not be met with L”
From Quantifying atherogenic lipoproteins for lipid-lowering strategies: Consensus-based recommendations from EAS and EFLM (2020) · cites this paper as [69]
LDLC and non-HDLC measurements or calculations cannot meet important prerequisites for medical use of a test (accuracy, harmonisation, unambiguous definition of the measurand, and unequivocal test results).
“important prerequisites for medical use of a test which can not be met with LDLC and non-HDLC measurements or calculations.”
From Quantifying atherogenic lipoproteins for lipid-lowering strategies: Consensus-based recommendations from EAS and EFLM (2020) · cites this paper as [69]
Cites
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Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target
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Vitamin E in Health and Disease
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A failure of standardization or a failure of the process of standardization
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Apolipoprotein B in Primary Prevention: Ready for Time Prime?
Quispe, R., Varghese, B. T., & Martin, S. S. (2022) · Contemporary cardiology · doi:10.1007/978-3-030-98824-1_18
- Authors
- Contois, J. H., & Delatour, V.
- Affiliations
- Ocean Alliance (US)
- Laboratoire National de Métrologie et d'Essais (FR)
- Corresponding author
- Contois, John H.
- Venue
- Journal of clinical lipidology
- Publisher
- Elsevier BV
- Published
- 2018-03
- Volume
- 12
- Issue
- 2
- Pages
- 264-265
- ISSN
- 1876-4789 (ISSN-L)
- 1933-2874
- OpenAlex
- W2788580632
- Cited by
- 15
- References
- 13
- Citations by year
- 2026: 1 · 2023: 1 · 2022: 1 · 2021: 6 · 2020: 1 · 2019: 2 · 2018: 3
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of clinical lipidology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Physiology › Clinical Laboratory Practices and Quality Control
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- apolipoprotein B, LDL particle number, small dense LDL, atherosclerotic cardiovascular disease risk, metabolic syndrome, diabetes mellitus, hypertriglyceridemia
- MeSH terms
- Apolipoproteins A, Apolipoproteins B, Coronary Disease, Follow-Up Studies, Humans, Atherosclerosis
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