The clinical effectiveness of cognitive therapy for depression in an outpatient clinic
Open accessAbstract
Background Cognitive therapy (CT) has been shown to be efficacious in the treatment of depression in numerous randomized controlled trials (RCTs). However, little evidence is available that speaks to the effectiveness of this treatment under routine clinical conditions. Method This paper examines outcomes of depressed individuals seeking cognitive therapy at an outpatient clinic (N=217, Center for Cognitive Therapy; CCT). Outcomes were then compared to those of participants in a large NIMH-funded RCT of cognitive therapy and medications as treatments for depression. Results The CCT is shown to be a clinically representative setting, and 61% of participants experienced reliable change in symptoms over the course of treatment; of those, 45% (36% of the total sample) met criteria for recovery by the end of treatment. Participants at CCT had similar outcomes to participants treated in the RCT, but there was some evidence that those with more severe symptoms at intake demonstrated greater improvement in the RCT than their counterparts at CCT. Limitations The CCT may not be representative of all outpatient settings, and the structure of treatment there was considerably different from that in the RCT. Treatment fidelity was not assessed at CCT. Conclusions Depressed individuals treated with cognitive therapy in a routine clinical care setting showed a significant improvement in symptoms. When compared with outcomes evidenced in RCTs, there was little evidence of superior outcomes in either setting. However, for more severe participants, outcomes were found to be superior when treatment was delivered within an RCT than in an outpatient setting. Clinicians treating such patients in non-research settings may thus benefit from making modifications to treatment protocols to more closely resemble research settings.
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RCTs include procedures that are often very different from the delivery of interventions in routine practice.
“While RCTs are accepted as the 'gold standard' for intervention research, they include procedures that are often very different to the delivery of the interventions in routine practice (Gibbons et al ., 2010).”
From Supervisor practice when guiding therapists working with depression: The impact of supervisor and patient characteristics (2018) · cites this paper as Gibbons et al ., 2010
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- Authors
- Gibbons, C. J., Fournier, J. C., Stirman, S. W., DeRubeis, R. J., Crits-Christoph, P., & Beck, A. T.
- Affiliations
- Yale University (US)
- University of Pennsylvania (US)
- Boston University (US)
- Corresponding author
- Gibbons, Carly J.
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2010-09
- Volume
- 125
- Issue
- 1-3
- Pages
- 169-176
- ISSN
- 0165-0327 (ISSN-L)
- PMC
- PMC2888955
- OpenAlex
- W2059593063
- Cited by
- 46
- References
- 38
- Citations by year
- 2022: 2 · 2020: 2 · 2019: 6 · 2018: 1 · 2017: 4 · 2016: 3 · 2015: 6 · 2014: 4 · 2013: 5 · 2012: 7
- FWCI
- 7.54
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- U.S. Public Health Service (R49/CCR316866)
- National Institute of Mental Health (R10 MH55875, R00MH080100, R37MH047383, R10 MH50129, K02 MH01697, K02MH001697, MH47383, R10MH055875, K99MH080100, R10MH055877)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
- Keywords
- cognitive therapy, depression, outpatient care, clinical effectiveness, routine clinical practice, intervention fidelity, symptom recovery, treatment protocol modification, symptom severity
- MeSH terms
- Adult, Ambulatory Care, Antidepressive Agents, Combined Modality Therapy, Depressive Disorder, Major, Major Depressive Disorder, Female, Humans, Longitudinal Studies, Male, Middle Aged, Personality Inventory, Psychometrics, Reproducibility of Results, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic, Young Adult
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