A survey of patient acceptability of repetitive transcranial magnetic stimulation (TMS) during pregnancy
Open accessAbstract
Objective Given the data that depression is common during pregnancy and that pregnant women prefer non-medication treatment options, we hypothesize repetitive transcranial magnetic stimulation (TMS) may be a treatment option. Given the novelty of TMS, we sought to assess whether patient acceptability would be a barrier to enrolling pregnant women in TMS studies. Methods In Study 1, 500 pregnant women were surveyed in an outpatient, urban obstetrics clinic using the Edinburgh Depression Rating Scale (EPDS) and a treatment acceptability survey. In Study 2, 51 women were surveyed with the EPDS and acceptability survey using an informational video to increase participant knowledge about TMS. Results Approximately 25% of participants had an EPDS score of ≥12 in both studies. Psychotherapy was identified as the most acceptable treatment option. TMS was considered an unacceptable treatment option to virtually all women before the informational video. After the video, 15.7% considered TMS an acceptable treatment option. Conclusion Psychotherapy is the most acceptable treatment option for depression to pregnant women. Increasing participant knowledge about TMS increased its acceptability significantly. Large-scale multi-center trials are needed for confirmation of these results.
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Pregnant and postpartum women face unique barriers to obtaining nonmedication treatment such as psychotherapy, including lack of childcare, lack of time, limitations in mobility or transportation, stigma associated with depression during pregnancy, and financial concerns.
“they also face unique barriers to obtaining such treatment, including lack of childcare, lack of time, limitations in mobility or transportation, stigma associated with depression during pregnancy, and financial concerns.17–21”
From Pregnancy and the Acceptability of Computer-Based Versus Traditional Mental Health Treatments (2017) · cites this paper as [18]
The Discussion reports childcare, time, transportation, stigma, and inability to pay as barriers to mental health care for pregnant women; the Results also identify transportation and work schedules as barriers. The passages do not establish these barriers specifically for postpartum women or identify limited mobility as a barrier, and they discuss treatment broadly rather than psychotherapy alone. (LLM, conf=0.84)
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Jackson, J. R., & Decesare, J. Z. (2017) · Cambridge University Press eBooks · doi:10.1017/9781316662571.028
- Authors
- Kim, D. R., Sockol, L., Barber, J. P., Moseley, M., Lamprou, L., Rickels, K., O'Reardon, J. P., & Epperson, C. N.
- Affiliations
- University of Pennsylvania (US)
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2011-03
- Volume
- 129
- Issue
- 1-3
- Pages
- 385-390
- ISSN
- 0165-0327 (ISSN-L)
- PMC
- PMC4109278
- OpenAlex
- W2013424667
- Cited by
- 122
- References
- 16
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 3 · 2023: 2 · 2022: 2 · 2021: 6 · 2020: 5 · 2019: 4 · 2018: 2 · 2017: 62 · 2016: 1 · 2015: 6 · 2014: 6 · 2013: 5 · 2012: 6
- FWCI
- 2.71
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Drug Abuse (K24DA030301)
- Topics
- Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Psychiatry and Mental health › Electroconvulsive Therapy Studies
- Keywords
- repetitive transcranial magnetic stimulation, pregnancy, antenatal depression, treatment acceptability, patient preferences, psychotherapy, informational videos, participant knowledge, non-pharmacological treatment, Edinburgh Postnatal Depression Scale
- MeSH terms
- Adolescent, Adult, Data Collection, Depressive Disorder, Female, Gestational Age, Humans, Patient Acceptance of Health Care, Patient Education as Topic, Pregnancy, Pregnancy Complications, Psychotherapy, Surveys and Questionnaires, Odds Ratio, Transcranial Magnetic Stimulation, Young Adult
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