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Relationship between physical activity and depression and anxiety symptoms: A population study
Abstract
Background There are few studies evaluating the association between practice of physical activity and mood in a population sample. This study evaluated the frequency of symptoms of depression and anxiety in the population of the city of Sao Paulo and their association with the report of practice of regular physical activity.Methods This survey was conducted with the adult population of Sao Paulo between July and December of 2007. The sample was composed of 1042 volunteers (both genders) with a mean age of 41.9±14.4 years. The volunteers were evaluated using the Beck Depression Inventory, the Beck Anxiety Inventory, and two simple questions designed to evaluate and classify physical activity. Socioeconomic status was also determined according to Brazil's Economic Classification Criterion.Results People who do not engage in physical activity are two times more likely to exhibit symptoms of depression (PR: 2.1) and anxiety (PR: 2.5) compared with those who regularly practice physical activity and a higher prevalence of symptoms for anxiety (9.8%) and depression (10.9%) was observed among those claiming to not practice regular physical activity and 63.2% related did not practice any physical activity regularly.Conclusion Altogether, these results suggest that people who do not practice physical activity have a higher chance of exhibiting symptoms of depression and anxiety when compared to those who perform physical activity regularly. In this sense, regular physical activity must be encouraged, and this incentive should be routine in both current and future public health policies. Although the methodology in the present study does not allow assigning a relation of cause and effect, we observed associations between symptoms of depression, anxiety and physical activity.
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“Several studies have found that physical activity is negatively associated with depression/anxiety disorders and poor physical health outcomes (Gerber and Puehse 2009;De Mello et al., 2013;Durstine et al., 2013;Wang et al., 2014;Hegberg and Tone, 2015).”
From The relationship between physical and mental health: A mediation analysis (2017) · cites this paper as De Mello et al., 2013
In the citing paper
“Several studies of the general population have found that people who engage in more PA have a reduced risk of being diagnosed with an anxiety disorder and less frequent and severe anxiety symptoms [47–52].”
From Moving to Beat Anxiety: Epidemiology and Therapeutic Issues with Physical Activity for Anxiety (2018) · cites this paper as [49]
In the citing paper
“Recent epidemiological data further suggests that people who are more active may be less likely to have anxiety disorders.”
From Moving to Beat Anxiety: Epidemiology and Therapeutic Issues with Physical Activity for Anxiety (2018) · cites this paper as [49]
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Arslan, N., Ayyıldız, F., & Esin, K. (2025) · Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi · doi:10.37989/gumussagbil.1772473
Junger, A. F., de Oliveira, G. S., Viana, M. V., Pinheiro, M. D. A., Fortes, P. F. C., Rica, R. L., Bullo, V., Gobbo, S., Bergamin, M., & Bocalini, D. S. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1736902
Sex differences in regulatory mechanisms of the cardiovascular system during simulated hypokinesia
Fedchuk, M. V., Nosovsky, A. M., & Rusanov, V. P. (2026) · Life Sciences in Space Research · doi:10.1016/j.lssr.2026.03.003
Metadata
- Authors
- De Mello, M. T., Lemos, V. D. A., Antunes, H. K. M., Bittencourt, L., Santos-Silva, R., & Tufik, S.
- Affiliations
- Universidade Federal de São Paulo (BR)
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2013-07
- Volume
- 149
- Issue
- 1-3
- Pages
- 241-246
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W2134056983
- Cited by
- 209
- References
- 43
- Citations by year
- 2026: 11 · 2025: 19 · 2024: 23 · 2023: 13 · 2022: 17 · 2021: 25 · 2020: 33 · 2019: 18 · 2018: 12 · 2017: 11 · 2016: 7 · 2015: 9 · 2014: 11
- FWCI
- 6.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- UNIFESP Institutional Repository (Universidade Federal de São Paulo) (submittedVersion)
- Funders
- Associação Fundo de Incentivo a Pesquisa (AFIP)
- Centro Multidisciplinar em Sonolência e Acidentes (CEMSA)
- Centro de Estudos em Psicobiologia e Exercício (CEPE)
- FADA/Unifesp, Instituto do Sono, Fundação de Amparo a Pesquisa do Estado de São Paulo (FAPESP)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Keywords
- physical activity, depression, anxiety, mood, mental health, socioeconomic status, public health policy
- MeSH terms
- Adult, Aged, Aged, 80 and over, Anxiety, Brazil, Depression, Female, Humans, Male, Middle Aged, Motor Activity, Prevalence
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