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Validation studies of the Edinburgh Postnatal Depression Scale for the antenatal period
Abstract
Background Relatively few studies have focused on the validation of psychometric scales measuring depression during pregnancy. The aim of this review was to critically appraise and review antenatal validation studies of the Edinburgh Postnatal Depression Scale (EPDS).Methods A systematic search was performed in MEDLINE, EMBASE, ISI, CINAHL, SCIELO and PsyCINFO for the period 1987-2013.Results Eleven validation studies met the inclusion criteria. The study design varied between studies. Sensitivity and specificity estimates also varied between 64-100% and 73-100%, respectively. The confidence interval estimates also showed a high degree of variability. Our estimates suggest lower positive predictive values in the general population than those reported in the validation study samples. The sensitivity values in validation studies of the EPDS show fairly large variability, ranging from good to acceptable.Limitations Future studies should have larger sample sizes and include both representative and clinical samples and look at the psychometric performance of the EPDS in each trimester.Conclusions Due to differences in study design and variation in the cultural/linguistic adaptation, uncertainty remains regarding the comparability of the sensitivity and specificity estimates of different EPDS versions. Future studies should have larger sample sizes, include both representative and clinical samples, and look at the psychometric performance of the EPDS in each trimester. Reporting quality, especially as regards checks to ensure content validity, should be improved.
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“The EDS has been validated as a screening instrument for prenatal and postpartum depression, showing good psychometric properties [29].”
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Shui, H., Cao, X., & 张雪梅 (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15124465
Nakanishi, C., Diaz-Howard, A. M., & Mendenhall, T. J. (2026) · Contemporary Family Therapy · doi:10.1007/s10591-026-09791-1
Metadata
- Authors
- Kozinszky, Z., & Dudas, R. B.
- Affiliations
- Norfolk and Suffolk NHS Foundation Trust (GB)
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2015-05
- Volume
- 176
- Pages
- 95-105
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W1969116346
- Cited by
- 307
- References
- 84
- Citations by year
- 2026: 21 · 2025: 24 · 2024: 31 · 2023: 27 · 2022: 34 · 2021: 41 · 2020: 37 · 2019: 26 · 2018: 22 · 2017: 20 · 2016: 17 · 2015: 7
- FWCI
- 3.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- Repository of the Academy's Library (Library of the Hungarian Academy of Sciences) (acceptedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Nursing › Research and Theory › Health Education and Validation
- Keywords
- Edinburgh Postnatal Depression Scale, antenatal depression, depression screening, psychometric validation, sensitivity and specificity, positive predictive value, pregnancy, scale adaptation, content validity
- MeSH terms
- Major Depressive Disorder, Female, Humans, Pregnancy, Pregnancy Complications, Psychiatric Status Rating Scales, Psychometrics, Validation Studies as Topic
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