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Cited by 154Digital Mental Health InterventionsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMental Health Treatment and Access

The DOI matches its Crossref record; 44 of the 46 references it cites were found in a registry or an index.

Evaluating an e-mental health program (“deprexis”) as adjunctive treatment tool in psychotherapy for depression: Results of a pragmatic randomized controlled trial

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Berger, Thomas, Krieger, Tobias, Sude, Kerstin, Meyer, Björn, Maercker, Andreas·2018·Journal of Affective Disorders
DOI 10.1016/j.jad.2017.11.021
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Abstract

Background Depressive disorders place a significant disease burden on individuals as well as on societies. Several web-based interventions for depression have shown to be effective in reducing depressive symptoms. However, it is not known whether web-based interventions, when used as adjunctive treatment tools to regular psychotherapy, have an additional effect compared to regular psychotherapy for depression.Methods Adults (N = 98) with a unipolar affective disorder were recruited in routine outpatient psychotherapy practices in Germany from therapists over the course of their initial sessions and randomized within therapists to one of two active treatment conditions: regular psychotherapy or psychotherapy plus a web-based depression program ("deprexis"). Primary outcome was depressive symptoms measured with the Beck Depression Inventory (BDI-II) at 12 weeks. Secondary outcomes were anxiety symptoms, somatic symptoms and quality of life at 12 weeks and six months follow-up. The study also included an assessment of the working alliance after six and 12 weeks.Results The combination of psychotherapy with the web-based program was more effective than psychotherapy alone at 12 weeks, with medium between-group effect sizes on primary depressive symptoms (Cohen's d = .51) and small to medium between-group effect sizes on secondary outcomes (Cohen's d = .07-.55). Furthermore, we did not observe negative side effects in the blended format, e.g., a lower working alliance than in psychotherapy alone.Limitations The study had a smaller than planned sample size and the dropout rate at follow-up was high.Conclusions This study provides first evidence that the use of a web-based program as an adjunctive tool in regular psychotherapy could be a promising option to consider in future treatment for depression.

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Research works printed but not linked: 2

  1. Klein, 2016, Effects of a psychological internet intervention in the treatment of mild to moderate depressive symptoms: results of the EVIDENT study, a randomized controlled trial, Psychother. Psychosom., 85, 218, 10.1159/000445355 · DOI
  2. Schröder, 2017, Attitudes towards internet interventions among psychotherapists and study participants with mild to moderate depression symptoms, Cogn. Behav. Ther., 41, 745

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Metadata

Authors
Berger, T., Krieger, T., Sude, K., Meyer, B., & Maercker, A.
Affiliations
  • University of Bern (CH)
  • City, University of London (GB)
Corresponding author
Berger, Thomas
ORCID
Venue
Journal of Affective Disorders
Publisher
Elsevier BV
Published
2018-02
Volume
227
Pages
455-462
ISSN
0165-0327 (ISSN-L)
DOI
10.1016/j.jad.2017.11.021
OpenAlex
W2767843933
Cited by
153
References
46
Citations by year
2026: 15 · 2025: 18 · 2024: 14 · 2023: 19 · 2022: 23 · 2021: 17 · 2020: 19 · 2019: 15 · 2018: 12
FWCI
14.68
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Affective Disorders (acceptedVersion)
  • PubMed (publishedVersion)
  • BORIS (University Library Bern) (submittedVersion)
  • Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
Funders
  • Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (PP00P1_144824/1)
  • European Commission
Topics
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Keywords
depression, e-mental health, online intervention, Deprexis, adjunctive therapy, psychotherapy, blended treatment, therapeutic relationship, depressive symptoms, anxiety symptoms, somatic symptoms, quality of life, unipolar affective disorder
MeSH terms
Adult, Combined Modality Therapy, Major Depressive Disorder, Female, Germany, Humans, Male, Middle Aged, Psychotherapy, Software, Somatoform Disorders, Therapy, Computer-Assisted, Internet

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