The lethality of suicide methods: A systematic review and meta-analysis
Open accessAbstract
Background The use of suicide methods largely determines the outcome of suicide acts. However, no existing meta-analysis has assessed the case fatality rates (CFRs) by different suicide methods. The current study aimed to fill this gap. Methods We searched Scopus, Web of Science, PubMed, ProQuest and Embase for studies reporting method-specific CFRs in suicide, published from inception to 31 December 2020. A random-effect model meta-analysis was applied to compute pooled estimates. Results Of 10,708 studies screened, 34 studies were included in the meta-analysis. Based on the suicide acts that resulted in death or hospitalization, firearms were found to be the most lethal method (CFR:89.7%), followed by hanging/suffocation (84.5%), drowning (80.4%), gas poisoning (56.6%), jumping (46.7%), drug/liquid poisoning (8.0%) and cutting (4.0%). The rank of the lethality for different methods remained relatively stable across study setting, sex and age group. Method-specific CFRs for males and females were similar for most suicide methods, while method-CFRs were specifically higher in older adults. Conclusions This study is the first meta-analysis that provides significant evidence for the wide variation of the lethality of suicide methods. Restricting highly lethal methods based on local context is vital in suicide prevention.
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90% of firearm suicide attempts result in death.
“First, many patients with firearm injuries die at the scene, especially those who used a firearm to attempt suicide, 90% of which result in death [22].”
From Firearm injuries in Missouri (2023) · cites this paper as [22]
Many patients with firearm injuries die at the scene, especially those who used a firearm to attempt suicide.
“First, many patients with firearm injuries die at the scene, especially those who used a firearm to attempt suicide, 90% of which result in death [22].”
From Firearm injuries in Missouri (2023) · cites this paper as [22]
Cites
The PRISMA 2020 statement: an updated guideline for reporting systematic reviews
Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., et al. (2021) · Systematic Reviews · doi:10.1186/s13643-021-01626-4 · Cited by 13,874 · see citing works
Risk factors for suicidal thoughts and behaviors: A meta-analysis of 50 years of research
Franklin, J. C., Ribeiro, J. D., Fox, K. R., Bentley, K. H., Kleiman, E. M., Huang, X., Musacchio, K. M., Jaroszewski, A. C., Chang, B. P., & Nock, M. K. (2017) · Psychological Bulletin · doi:10.1037/bul0000084 · Cited by 3,784 · see citing works
Methods to estimate the between‐study variance and its uncertainty in meta‐analysis
Veroniki, A. A., Jackson, D., Viechtbauer, W., Bender, R., Bowden, J., Knapp, G., Kuss, O., Higgins, J. P., Langan, D., & Salanti, G. (2016) · Research Synthesis Methods · doi:10.1002/jrsm.1164 · Cited by 1,685 · see citing works
Suicide by intentional ingestion of pesticides: a continuing tragedy in developing countries
Gunnell, D., & Eddleston, M. (2003) · International Journal of Epidemiology · doi:10.1093/ije/dyg307 · Cited by 643 · see citing works
Suicide: A 15‐Year Review of the Sociological Literature Part I: Cultural and Economic Factors
Stack, S. (2000) · Suicide and Life-Threatening Behavior · doi:10.1111/j.1943-278x.2000.tb01073.x · Cited by 503 · see citing works
Association between suicide reporting in the media and suicide: systematic review and meta-analysis
Niederkrotenthaler, T., Braun, M., Pirkis, J., Till, B., Stack, S., Sinyor, M., Tran, U. S., Voracek, M., Cheng, Q., Arendt, F., et al. (2020) · BMJ · doi:10.1136/bmj.m575 · Cited by 363 · see citing works
Self-citationReducing a Suicidal Person’s Access to Lethal Means of Suicide
Barber, C. W., & Miller, M. J. (2014) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2014.05.028 · Cited by 329 · see citing works
Suicide Case-Fatality Rates in the United States, 2007 to 2014: A Nationwide Population-Based Study
Conner, A., Azrael, D., & Miller, M. (2019) · Annals of Internal Medicine · doi:10.7326/m19-1324 · Cited by 286 · see citing works
Miller, M., Azrael, D., & Barber, C. (2012) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-031811-124636 · Cited by 265 · see citing works
Suicide prevention through means restriction: Assessing the risk of substitution
Daigle, M. S. (2005) · Accident Analysis & Prevention · doi:10.1016/j.aap.2005.03.004 · Cited by 263 · see citing works
Prevention of Firearm Suicide in the United States: What Works and What Is Possible
Mann, J. J., & Michel, C. A. (2016) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2016.16010069 · Cited by 208 · see citing works
Toxicity of antidepressants: rates of suicide relative to prescribing and non-fatal overdose
Hawton, K., Bergen, H., Simkin, S., Cooper, J., Waters, K., Gunnell, D., & Kapur, N. (2010) · British Journal of Psychiatry · doi:10.1192/bjp.bp.109.070219 · Cited by 192 · see citing works
Trends in the Incidence and Lethality of Suicidal Acts in the United States, 2006 to 2015
Wang, J., Sumner, S. A., Simon, T. R., Crosby, A. E., Annor, F. B., Gaylor, E., Xu, L., & Holland, K. M. (2020) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2020.0596 · Cited by 78 · see citing works
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Rivara, F. P., Hink, A. B., Kuhls, D., Banks, S., Agoubi, L. L., Kirkendoll, S., Winchester, A., Hoeft, C., Patel, B., & Nathens, A. (2023) · PLOS ONE · doi:10.1371/journal.pone.0294737 · Cited by 3 · see citing works
- Authors
- Cai, Z., Junus, A., Chang, Q., & Yip, P. S. F.
- Affiliations
- University of Hong Kong (HK)
- Xiamen University (CN)
- Hong Kong Jockey Club (HK)
- Corresponding author
- Chang, Qingsong
- Yip, Paul S.F.
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2022-03
- Volume
- 300
- Pages
- 121-129
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W4200170086
- Cited by
- 155
- References
- 13
- Citations by year
- 2026: 52 · 2025: 39 · 2024: 35 · 2023: 21 · 2022: 7
- FWCI
- 2.10
- Type
- journal article
- Language
- en
- Open access
- green
- doi.org
- Licence
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- Newcastle University ePrints (Newcastle Univesity)
- Funders
- The University of Hong Kong
- Xiamen University
- National Office for Philosophy and Social Sciences (21CSH057)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Injury Epidemiology and Prevention
- Keywords
- suicide methods, case fatality rate, firearms, drowning, gas poisoning, drug poisoning, suicide prevention, sex differences, older adults
- MeSH terms
- Aged, Drowning, Female, Firearms, Gas Poisoning, Hospitalization, Humans, Male, Suicide
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