The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Association of Five-Factor Model Personality Domains and Facets with Presence, Onset, and Treatment Outcomes of Major Depression in Older Adults
Open accessAbstract
Objectives To assess the relationship of multiple domains and facets of the five-factor model of personality with presence, onset, and severity of late-life depression.Design Cross-sectional analysis of depression status, and age of onset. Retrospective analysis of baseline severity. Longitudinal analysis of severity after 3 and 12 months of psychiatric treatment.Setting Private university-affiliated medical center in the Southeastern United States.Participants One hundred twelve psychiatric patients with a current episode of unipolar major depression, and 104 nondepressed comparison subjects, age 60 and older (mean: 70, SD: 6).Measurements Revised NEO Personality Inventory, Diagnostic Interview Schedule, and Montgomery-Åsberg Depression Rating Scale.Results Binary logistic regression found that depression was related to higher neuroticism (and all its facets) and to lower extraversion (and facets of assertiveness, activity, and positive emotionality) and conscientiousness (and facets of competence, order, dutifulness, and self-discipline). Multinomial logistic regression found some of these relationships held only for depression with onset before age 50 (hostility, self-consciousness, extraversion, assertiveness, positive emotions, order, and dutifulness). Linear regression found that personality was unrelated to depression severity at the beginning of treatment, but improvement after 3 months was related to lower neuroticism (and facets depressiveness and stress-vulnerability) and higher warmth and competence. Improvement after 12 months was related to lower neuroticism, depressiveness, and stress-vulnerability.Conclusions Specific personality facets are related with depression and treatment outcomes. Screening for certain personality traits at the start of treatment may help identify patients at risk of worse response to treatment after 3 months.
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“The present findings replicate and extend existing evidence for the impact of neuroticism, and VS specifically, on both treatment response and cognitive decline in LLD (18, 19).”
From Neuroticism Traits Selectively Impact Long Term Illness Course and Cognitive Decline in Late-Life Depression (2017) · cites this paper as [19]
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“Our preliminary evidence indicated high total neuroticism and the VS trait were the only neuroticism scores associated with both a worse one-year antidepressant treatment response and a two-year decline in global cognitive functioning in LLD (18, 19).”
From Neuroticism Traits Selectively Impact Long Term Illness Course and Cognitive Decline in Late-Life Depression (2017) · cites this paper as [19]
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Depression in older adults: Testing the behavioral model of onset and maintenance
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Metadata
- Authors
- Hayward, R. D., Taylor, W. D., Smoski, M. J., Steffens, D. C., & Payne, M. E.
- Affiliations
- University of Michigan (US)
- Duke Medical Center (US)
- Corresponding author
- Hayward, R. David
- Venue
- The American Journal of Geriatric Psychiatry
- Publisher
- Elsevier BV
- Published
- 2013-01
- Volume
- 21
- Issue
- 1
- Pages
- 88-96
- ISSN
- 1064-7481 (ISSN-L)
- PMC
- PMC3382026
- OpenAlex
- W1965180119
- Cited by
- 119
- References
- 41
- Citations by year
- 2026: 2 · 2025: 7 · 2024: 15 · 2023: 12 · 2022: 9 · 2021: 7 · 2020: 11 · 2019: 11 · 2018: 8 · 2017: 7 · 2016: 8 · 2015: 8 · 2014: 6 · 2013: 8
- FWCI
- 11.13
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Geriatric Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (MH60451, K24MH070027, MH70027, R01MH054846, MH-54846, K23MH087754, P50MH060451)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- Big Five personality traits, personality facets, geriatric depression, major depressive disorder, neuroticism, extraversion, conscientiousness, depression onset, depression severity, treatment response, personality screening, older adults
- MeSH terms
- Aged, Depressive Disorder, Major, Major Depressive Disorder, Female, Humans, Longitudinal Studies, Male, Models, Psychological, Personality, Personality Inventory, Retrospective Studies, Severity of Illness Index, Treatment Outcome, Age of Onset
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