Cited by 104Suicide and Self-Harm StudiesPsychotherapy Techniques and ApplicationsAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Problem-Solving Therapy Reduces Suicidal Ideation In Depressed Older Adults with Executive Dysfunction

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Gustavson, Kristen A., Alexopoulos, George S., Niu, Grace C., McCulloch, Charles, Meade, Tanya, Areán, Patricia A.·2016·The American Journal of Geriatric Psychiatry

Abstract

Objective To test the hypothesis that Problem Solving Therapy (PST) is more effective than Supportive Therapy (ST) in reducing suicidal ideation in older adults with major depression and executive dysfunction. We further explored whether patient characteristics, such as age, sex, and additional cognitive impairment load (e.g., memory impairments) were related to changes in suicidal ideation over time.Design Secondary data analysis using data from a randomized clinical trial allocating participants to PST or ST at 1:1 ratio. Raters were blind to patients' assignments.Setting University medical centers.Participants 221 people aged 65 years old and older with major depression determined by Structured Clinical Interview for DSM-III-R diagnosis and executive dysfunction as defined by a score of 33 or less on the Initiation-Perseveration Score of the Mattis Dementia Rating Scale or a Stroop Interference Task score of 25 or less.Interventions 12 weekly sessions of PST or ST.Main outcome measures The suicide item of the Hamilton Depression Rating Scale.Results Of the 221 participants, 61% reported suicidal ideation (SI). The ST group had a lower rate of improvement in SI after 12 weeks (44.6%) than did the PST group (60.4%, Fisher's exact test p = 0.031). Logistic regression showed significantly greater reductions in SI in elders who received PST at both 12 weeks (OR: .50, Z = -2.16, p = 0.031) and 36 weeks (OR: 0.5, Z = -1.96, p = 0.05) after treatment.Conclusions PST is a promising intervention for older adults who are at risk for suicide. ClinicalTrials.gov Identifier: NCT00052091.

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  • Problem-solving therapy was associated with a reduction in suicidal ideation at 12 and 36 weeks, compared with supportive therapy.

    “However, one study demonstrated that problem-solving therapy was associated with a reduction in suicidal ideation at 12 and 36 weeks, compared with supportive therapy 277 .”

    From Suicide and suicide risk (2019) · cites this paper as [277]

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Research works printed but not linked: 2

  1. [27]Arean PaK H C How to Do High Quality Psyhotherapy Research 2013 New York Oxford Press
  2. [34]Epping-Jordan JA U T The WHODAS-II: leveling the playing field for all disorders World Health Organization Mental Health Bulletin 2000 6 5 6

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Authors
Gustavson, K. A., Alexopoulos, G. S., Niu, G. C., McCulloch, C., Meade, T., & Areán, P. A.
Affiliations
  • University of California, San Francisco (US)
  • Weill Cornell Medicine (US)
  • Western Sydney University (AU)
  • University of Washington (US)
Corresponding author
Areán, Patricia A.
Venue
The American Journal of Geriatric Psychiatry
Publisher
Elsevier BV
Published
2016-01
Volume
24
Issue
1
Pages
11-17
ISSN
1064-7481 (ISSN-L)
OpenAlex
W1182846970
Cited by
104
References
52
Citations by year
2026: 6 · 2025: 6 · 2024: 11 · 2023: 7 · 2022: 10 · 2021: 11 · 2020: 13 · 2019: 13 · 2018: 10 · 2017: 11 · 2016: 5 · 2015: 1
FWCI
11.16
Type
journal article
Language
en
Open access
Locations
  • American Journal of Geriatric Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Funders
  • Eli Lilly and Company
  • Pfizer
  • Sunovion
  • H. Lundbeck A/S
  • National Institute of Mental Health (P30MH085943, MH019132, K24MH074717, R01MH063982, T32MH018261, T32MH019132)
  • National Institute on Minority Health and Health Disparities (L60 MD006267)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
  • Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
problem-solving therapy, suicidal ideation, major depressive disorder, older adults, executive dysfunction, supportive therapy, cognitive impairment, memory impairment, suicide risk
MeSH terms
Aged, Aged, 80 and over, Cognition Disorders, Major Depressive Disorder, Female, Humans, Male, Middle Aged, Problem Solving, Psychiatric Status Rating Scales, Psychotherapy, Treatment Outcome, Diagnostic and Statistical Manual of Mental Disorders, Executive Function, Suicidal Ideation

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