Cited by 1,115Nutritional Studies and DietDementia and Cognitive Impairment ResearchFatty Acid Research and Health

The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.

MIND diet slows cognitive decline with aging

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Abstract

Introduction: The Mediterranean and dash diets have been shown to slow cognitive decline; however, neither diet is specific to the nutrition literature on dementia prevention. Methods: We devised the Mediterranean‐Dietary Approach to Systolic Hypertension (DASH) diet intervention for neurodegenerative delay (MIND) diet score that specifically captures dietary components shown to be neuroprotective and related it to change in cognition over an average 4.7 years among 960 participants of the Memory and Aging Project. Results: In adjusted mixed models, the MIND score was positively associated with slower decline in global cognitive score (β = 0.0092; P < .0001) and with each of five cognitive domains. The difference in decline rates for being in the top tertile of MIND diet scores versus the lowest was equivalent to being 7.5 years younger in age. Discussion: The study findings suggest that the MIND diet substantially slows cognitive decline with age. Replication of these findings in a dietary intervention trial would be required to verify its relevance to brain health.

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Crossref · 10.1016/j.jalz.2015.04.011

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  1. 2015, Changing the trajectory of Alzheimer's disease: How a treatment by 2025 saves lives and dollars

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Metadata

Authors
Morris, M. C., Tangney, C. C., Wang, Y., Sacks, F. M., Barnes, L. L., Bennett, D. A., & Aggarwal, N. T.
Affiliations
  • Rush University Medical Center (US)
  • Harvard University (US)
Corresponding author
Morris, Martha Clare
Venue
Alzheimer's & Dementia
Publisher
Wiley
Published
2015-06-15
Volume
11
Issue
9
Pages
1015-1022
ISSN
  • 1552-5260 (ISSN-L)
  • 1552-5279
OpenAlex
W1893987280
Cited by
1,115
References
54
Citations by year
2026: 159 · 2025: 167 · 2024: 145 · 2023: 126 · 2022: 125 · 2021: 99 · 2020: 125 · 2019: 58 · 2018: 55 · 2017: 36 · 2016: 17 · 2015: 2
FWCI
39.23
Type
journal article
Language
en
Open access
Locations
  • Alzheimer s & Dementia (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
Funders
National Institute on Aging (R01AG031553, R01AG17917)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
Keywords
MIND diet, cognitive decline
MeSH terms
Aged, 80 and over, Aging, Chicago, Cognition Disorders, Diet Surveys, Female, Humans, Male, Prospective Studies, Psychological Tests, Linear Models, Disease Progression, Diet, Mediterranean

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