2019 Alzheimer’s disease facts and figures.

Alzheimer's Association

doi:10.1016/j.jalz.2019.01.010

Cited by 2,461Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatmentsGeriatric Care and Nursing Homes

2019 Alzheimer’s disease facts and figures.

Alzheimer's Association·2019·Alzheimer's & Dementia

DOI 10.1016/j.jalz.2019.01.010

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Abstract

This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, use and costs of care, and the overall impact on caregivers and society. The Special Report examines the use of brief cognitive assessments by primary care physicians as a tool for improving early detection of dementia. An estimated 5.8 million Americans have Alzheimer's dementia. By mid‐century, the number of people living with Alzheimer's dementia in the United States may grow to 13.8 million, fueled in large part by the aging baby boom generation. In 2017, official death certificates recorded 121,404 deaths from AD, making AD the sixth leading cause of death in the United States and the fifth leading cause of death among Americans age ≥65 years. Between 2000 and 2017, deaths resulting from stroke, heart disease, and prostate cancer decreased, whereas reported deaths from AD increased 145%. In 2018, more than 16 million family members and other unpaid caregivers provided an estimated 18.5 billion hours of care to people with Alzheimer's or other dementias. This care is valued at nearly $234 billion, but its costs extend to family caregivers' increased risk for emotional distress and negative mental and physical health outcomes. Average per‐person Medicare payments for services to beneficiaries age ≥65 years with Alzheimer's or other dementias are more than three times as great as payments for beneficiaries without these conditions. Total payments in 2019 for health care, long‐term care and hospice services for people age ≥65 years with dementia are estimated to be $290 billion. Early detection of Alzheimer's offers numerous medical, emotional and financial benefits—benefits that accrue to affected individuals and their families as well as to society at large. Alzheimer's Association surveys regarding brief cognitive assessments for detection of dementia found that while a large majority of seniors and primary care physicians say the assessments are important, only half of seniors have received an assessment, and only 16 percent of seniors receive regular cognitive assessments. Many educational opportunities exist to facilitate increased use of brief cognitive assessments in the primary care setting.

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FTD and AD are the two most common types of dementia in the younger-elderly population.
“precise identification of FTD and AD, which are the two most common types of dementia in the younger-elderly population (Bang et al., 2015; Association, 2019), is of vital clinical significance in the diagnosis of dementias.”
From Deep Learning-Based Classification and Voxel-Based Visualization of Frontotemporal Dementia and Alzheimer's Disease (2021) · cites this paper as Association, 2019

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Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
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Alzheimer’s Disease: Key Insights from Two Decades of Clinical Trial Failures
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Tip of the Iceberg: Assessing the Global Socioeconomic Costs of Alzheimer’s Disease and Related Dementias and Strategic Implications for Stakeholders
El-Hayek, Y. H., Wiley, R. E., Khoury, C. P., Daya, R. P., Ballard, C., Evans, A. R., Karran, M., Molinuevo, J. L., Norton, M., & Atri, A. (2019) · Journal of Alzheimer's Disease · doi:10.3233/jad-190426 · Cited by 216 · see citing works
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Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia
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Association of Neighborhood-Level Disadvantage With Alzheimer Disease Neuropathology
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GABAergic Inhibitory Interneuron Deficits in Alzheimer’s Disease: Implications for Treatment
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Deep learning for Alzheimer's disease diagnosis: A survey
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Authors: Alzheimer's Association
Corresponding author: Alzheimer's Association
Venue: Alzheimer's & Dementia
Publisher: Wiley
Published: 2019-03
Volume: 15
Issue: 3
Pages: 321-387
ISSN: 1552-5260 (ISSN-L)
1552-5279
DOI: 10.1016/j.jalz.2019.01.010
OpenAlex: W4211139529
Cited by: 2,461
References: 496
Citations by year: 2026: 108 · 2025: 214 · 2024: 245 · 2023: 310 · 2022: 357 · 2021: 558 · 2020: 544 · 2019: 120 · 2018: 2 · 2013: 1
FWCI: 316.68
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Alzheimer s & Dementia (publishedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
Health Sciences › Health Professions › General Health Professions › Geriatric Care and Nursing Homes
Keywords: Alzheimer's disease, dementia

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