Dietary changes and cognition over 2 years within a multidomain intervention trial—The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)
Open accessAbstract
Introduction: Association between healthy diet and better cognition is well established, but evidence is limited to evaluate the effect of dietary changes adopted in older age. Methods: We investigated the role of dietary changes in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) with 1260 at‐risk participants (60–77 years) who were randomized to intensive multidomain intervention (including dietary counseling) or regular health advice for 2 years. Parallel process latent growth curves of adherence to dietary recommendations and cognitive performance were analyzed. Results: Adherence to healthy diet at baseline predicted improvement in global cognition, regardless of intervention allocation (P = .003). Dietary improvement was associated with beneficial changes in executive function, especially in the intervention group (P = .008; P = .051 for groups combined). Discussion: Dietary changes initiated during the intervention were related to changes in executive function in 2 years. Long‐term diet appeared more influential for global cognition.
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Research shows a positive correlation between increased physical activity, cognitive training, improved nutrition, and slowing cognitive and functional decline and intensity of BPSD.
“Indeed, research shows a positive correlation between increased physical activity, cognitive training, improved nutrition, and slowing cognitive and functional decline and intensity of BPSD.”
From Alzheimer's Disease: Treatment Strategies and Their Limitations. (2022) · cites this paper as [169]
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Ngandu, T., Lehtisalo, J., Solomon, A., Levälahti, E., Ahtiluoto, S., Antikainen, R., Bäckman, L., Hänninen, T., Jula, A., Laatikainen, T., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(15)60461-5 · Cited by 3,689 · see citing works
Self-citationMIND diet slows cognitive decline with aging
Morris, M. C., Tangney, C. C., Wang, Y., Sacks, F. M., Barnes, L. L., Bennett, D. A., & Aggarwal, N. T. (2015) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2015.04.011 · Cited by 1,115 · see citing works
Loughrey, D. G., Lavecchia, S., Brennan, S., Lawlor, B. A., & Kelly, M. E. (2017) · Advances in Nutrition · doi:10.3945/an.117.015495 · Cited by 250 · see citing works
Soininen, H., Solomon, A., Visser, P. J., Hendrix, S. B., Blennow, K., Kivipelto, M., Hartmann, T., Hallikainen, I., Hallikainen, M., Helisalmi, S., et al. (2017) · The Lancet Neurology · doi:10.1016/s1474-4422(17)30332-0 · Cited by 241 · see citing works
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Alzheimer's Disease: Treatment Strategies and Their Limitations.
Passeri, E., Elkhoury, K., Morsink, M., Broersen, K., Linder, M., Tamayol, A., Malaplate, C., Yen, F. T., & Arab-Tehrany, E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232213954 · Cited by 592 · see citing works
The effect of adherence on cognition in a multidomain lifestyle intervention (FINGER)
Ngandu, T., Lehtisalo, J., Korkki, S., Solomon, A., Coley, N., Antikainen, R., Bäckman, L., Hänninen, T., Lindström, J., Laatikainen, T., et al. (2022) · Alzheimer's & Dementia · doi:10.1002/alz.12492 · Cited by 101 · see citing works
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- Authors
- Lehtisalo, J., Levälahti, E., Lindström, J., Hänninen, T., Paajanen, T., Peltonen, M., Antikainen, R., Laatikainen, T., Strandberg, T., Soininen, H., Tuomilehto, J., Kivipelto, M., & Ngandu, T.
- Affiliations
- University of Helsinki (FI)
- Finnish Institute for Health and Welfare (FI)
- Kuopio University Hospital (FI)
- Finnish Institute of Occupational Health (FI)
- Center for Life Course Health Research University of Oulu Oulu Finland
- University of Eastern Finland (FI)
- Universität für Weiterbildung Krems (AT)
- Stockholm University (SE)
- Karolinska Institutet (SE)
- Corresponding author
- Lehtisalo, Jenni
- ORCID
- Venue
- Alzheimer's & Dementia
- Publisher
- Wiley
- Published
- 2018-12-04
- Volume
- 15
- Issue
- 3
- Pages
- 410-417
- ISSN
- 1552-5260 (ISSN-L)
- 1552-5279
- OpenAlex
- W2903318173
- Cited by
- 95
- References
- 4
- Citations by year
- 2026: 9 · 2025: 8 · 2024: 13 · 2023: 13 · 2022: 13 · 2021: 17 · 2020: 15 · 2019: 6
- FWCI
- 7.48
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Alzheimer s & Dementia (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Työväentutkimus Vuosikirja (submittedVersion)
- Funders
- Juho Vainion Säätiö
- Novo Nordisk Fonden
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Keywords
- dietary change, healthy eating
- MeSH terms
- Aged, Cognition, Diet, Female, Finland, Humans, Male, Memory, Middle Aged, Patient Compliance, Treatment Outcome, Executive Function, Cognitive Dysfunction
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