Strategies and policies to address the opioid epidemic: a case study of Ohio
Open accessAbstract
OBJECTIVE: To describe the strategies and policies implemented in Ohio to improve opioid safety and to discuss the role that pharmacists can play in implementing, promoting, and enhancing the effectiveness of these policies. SETTING: Ohio has the fifth highest rate of drug overdose deaths (24.6 deaths per 100,000) in the United States. Unintentional drug overdose has become the leading cause of injury-related death in Ohio. In 2015, there were 3050 overdose deaths in Ohio, and in 2014 there were an estimated 12,847 overdose events reversed by emergency medical services with naloxone. PRACTICE DESCRIPTION: Not applicable. PRACTICE POLICY INNOVATION: In 2011, the Governor's Cabinet Opiate Action Team was created to implement a multifaceted strategy, in part (1) to promote the responsible use of opioids, (2) to reduce the supply of opioids, and (3) to support overdose prevention and expand access to naloxone. Innovations to assist these goals include the development of Ohio guidelines on the responsible use of opioids, mandatory use of Ohio's prescription drug monitoring program, closing pill mills, promotion of drug take-back programs and increased access to naloxone and public health campaigns. EVALUATION: Not applicable. RESULTS: Since the development of the Governor's Cabinet Opiate Action Team, there were 81 million fewer doses of opioids dispensed to Ohio patients in 2015 compared with 782 million doses dispensed in 2011. As such, the proportion of unintentional drug overdose deaths involving prescription opioids has reduced from 45% in 2011 to 22% in 2015. CONCLUSION: Strong political support was crucial in Ohio to facilitate the rapid implementation opioid overdose prevention programs and the promotion of public awareness campaigns. However, the misuse and abuse of prescription opioids are complex problems requiring a comprehensive and multifaceted approach. Pharmacists are identified as a crucial component of the state strategy to addressing opioid abuse by promoting responsible prescribing and adopting prevention practices.
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In 2016, Ohio passed a law that requires pharmacists to review a patient's PMDP history before dispensing a new controlled substance, encouraging denial to some patients and thereby taking a more proactive role in pain management.
“In 2016, Ohio passed a law that requires pharmacists to review a patient's PMDP history before dispensing a new controlled substance, encouraging denial to some patients and thereby taking a more proactive role in pain management (194).”
From A Biopsychosocial Overview of the Opioid Crisis: Considering Nutrition and Gastrointestinal Health (2019) · cites this paper as [194]
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Bennett, N. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.733207320.793556442
Curcillo, K., Drees, S. M., Najjar, J. A., Southard, E., Davis, A., Huss, C., & Singh, T. (2024) · Translation The University of Toledo Journal of Medical Sciences · doi:10.46570/utjms-2024-1158
Preventing Fentanyl-Related Overdose Deaths with Naloxone—A Medical Examiner Study
Alexander, G., Ferreira, P. A., Dean, S. A., & Alexander, R. T. (2025) · American Journal of Forensic Medicine & Pathology · doi:10.1097/paf.0000000000001028
Legislative Changes on Opioid Prescriptions for Ocular Procedures in a United States Cohort
Singh, P. T., Shaia, J. K., Rich, J. J., Zhang, D., Singh, R. P., & Talcott, K. E. (2025) · Ophthalmic surgery, lasers & imaging retina · doi:10.3928/23258160-20250127-04
CrossFit as Adjunctive Treatment in Substance Use Disorders
Klotzbaugh, R. J., Jakub, K., & Skrovanek, E. (2025) · Journal of Addictions Nursing · doi:10.1097/jan.0000000000000619
“Inclusion criteria for this (Penm et al., 2017; Ulloa, 2019).”
Wagi, C. R., Murphy, J., Enderle, M. N., Piscalko, H. M., Egan, K. L., Meade, C. S., Freisthler, B., Young, A. M., Estadt, A. T., & Lancaster, K. E. (2026) · Harm Reduction Journal · doi:10.1186/s12954-026-01450-w
“Although these data were collected in 2021, subsequent expansions in harm reduction services (e.g., nalox-one distribution and syringe services) and shifts in drug supply may have influenced current patterns of risk and service engagement [39, 40].”
Area-specific autoencoder spatiotemporal graph neural networks for opioid overdose death prediction
Chen, X., Yin, C., Myers, J. V., Slover, B., Thomas, N., Marks, C., Kim, J., Fernandez, S., Whitley, P., Fareed, N., et al. (2026) · JAMIA Open · doi:10.1093/jamiaopen/ooag063
- Authors
- Penm, J., MacKinnon, N. J., Boone, J. M., Ciaccia, A., McNamee, C., & Winstanley, E. L.
- Affiliations
- West Virginia University (US)
- Corresponding author
- Penm, Jonathan
- Venue
- Journal of the American Pharmacists Association
- Publisher
- Elsevier BV
- Published
- 2017-03
- Volume
- 57
- Issue
- 2
- Pages
- S148-S153
- ISSN
- 1544-3191 (ISSN-L)
- PMC
- PMC5497298
- OpenAlex
- W2587448567
- Cited by
- 73
- References
- 14
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 5 · 2023: 5 · 2022: 6 · 2021: 5 · 2020: 9 · 2019: 17 · 2018: 17 · 2017: 3
- FWCI
- 11.79
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of the American Pharmacists Association (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion, cc-by-nc-nd)
- PubMed Central (acceptedVersion, cc-by-nc-nd)
- The Research Repository @ WVU (West Virginia University) (submittedVersion)
- Funders
- National Institute of General Medical Sciences (U54GM104942)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Keywords
- opioid epidemic, prescription opioid misuse, opioid overdose prevention, naloxone access, prescription drug monitoring programs, drug take-back programs, drug overdose deaths
- MeSH terms
- Analgesics, Opioid, Health Policy, Health Services Accessibility, Humans, Naloxone, Narcotic Antagonists, Opioid-Related Disorders, Ohio, Pharmaceutical Services, Pharmacists, Public Health, Professional Role, Drug Overdose
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