Cited by 45Biomedical Text Mining and OntologiesMachine Learning in HealthcareMedical Coding and Health Information

Adaptation of an NLP system to a new healthcare environment to identify social determinants of health.

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Reeves, Ruth M., Christensen, Lee, Brown, Jeremiah R., Conway, Michael, Levis, Maxwell, Gobbel, Glenn T., Shah, Rashmee U., Goodrich, Christine +6 more·2021·Journal of Biomedical Informatics

Abstract

Social determinants of health (SDoH) are increasingly important factors for population health, healthcare outcomes, and care delivery. However, many of these factors are not reliably captured within structured electronic health record (EHR) data. In this work, we evaluated and adapted a previously published NLP tool to include additional social risk factors for deployment at Vanderbilt University Medical Center in an Acute Myocardial Infarction cohort. We developed a transformation of the SDoH outputs of the tool into the OMOP common data model (CDM) for re-use across many potential use cases, yielding performance measures across 8 SDoH classes of precision 0.83 recall 0.74 and F-measure of 0.78.

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  • In clinical practice, there has been a lack of systematic collection and analysis of SDoH defined in the EHRs.

    “In clinical practice, there has been a lack of systematic collection and analysis of SDoH defined in the EHRs15–17.”
  • More recent natural language processing (NLP)-based methods, particularly LLMs like GPT-4, have shown success in capturing SDoH information from unstructured clinical notes and patient narratives, yielding tangible benefits for patient outcomes.

    “More recent natural language processing (NLP)-based methods, particularly LLMs like GPT-4, have also shown success in capturing SDoH information from unstructured clinical notes and patient narratives, yielding tangible benefits for patient outcomes [78,79].”

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Research works printed but not linked: 3

  1. [12]National Academy of Medicine (formerly Institute of Medicine). Capturing Social and Behavioral Domains in Electronic Health Records: Phase 1. The National Academy Press; 2014. 24757748
  2. [13]National Academy of Medicine (formerly Institute of Medicine) Capturing Social and Behavioral Domains and Measures in Electronic Health Records: Phase 2. The National Academies Press; 2014. 25590118
  3. [33]National Academy of Medicine (formerly Institute of Medicine) Capturing Social and Behavioral Domains and Measures in Electronic Health Records: Phase 2. Washington (DC) 2015. 25590118

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Authors
Reeves, R. M., Christensen, L., Brown, J. R., Conway, M., Levis, M., Gobbel, G. T., Shah, R. U., Goodrich, C., Ricket, I., Minter, F., Bohm, A., Bray, B. E., Matheny, M. E., & Chapman, W.
Affiliations
  • VA Tennessee Valley Healthcare System (US)
  • University of Utah (US)
  • Dartmouth College (US)
  • Vanderbilt University Medical Center (US)
  • The University of Melbourne (AU)
Corresponding author
Reeves, Ruth M.
Venue
Journal of Biomedical Informatics
Publisher
Elsevier BV
Published
2021-08
Volume
120
Pages
103851
ISSN
1532-0464 (ISSN-L)
OpenAlex
W3177105417
Cited by
45
References
30
Citations by year
2026: 4 · 2025: 9 · 2024: 13 · 2023: 8 · 2022: 10 · 2021: 1
FWCI
2.51
Type
journal article
Language
en
Open access
Locations
  • Journal of Biomedical Informatics (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Heart, Lung, and Blood Institute (K08HL136850, R01HL130828)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biomedical Text Mining and Ontologies
  • Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
  • Health Sciences › Health Professions › Health Information Management › Medical Coding and Health Information
Keywords
social determinants of health, natural language processing, social risk factors, electronic health records, acute myocardial infarction, OMOP Common Data Model, clinical text mining, population health
MeSH terms
Academic Medical Centers, Delivery of Health Care, Humans, Cohort Studies, Electronic Health Records, Social Determinants of Health

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