Inflammation in Heart Failure With Preserved Ejection Fraction
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Myocardial damage induced by systemic inflammation is perpetrated by a pathologic EAT that adversely affects structure and function, intensifying cardiac inflammation, coronary microvascular dysfunction, and pro-fibrotic mechanisms, the pathologic hallmarks of HFpEF.
“As a consequence, the myocardial damage induced by systemic inflammation is perpetrated by a pathologic EAT that adversely affects structure and function intensifying cardiac inflammation, coronary microvascular dysfunction, and pro-fibrotic mechanisms, the pathologic hallmarks of HFpEF [93].”
From Dysregulated epicardial adipose tissue as a risk factor and potential therapeutic target of heart failure with preserved ejection fraction in diabetes (2022) · cites this paper as [93]
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- Authors
- Gomberg-Maitland, M., Shah, S. J., & Guazzi, M.
- Affiliations
- Northwestern University (US)
- University of Milan (IT)
- ORCID
- Guazzi, Marco
- Venue
- JACC Heart Failure
- Publisher
- Elsevier BV
- Published
- 2016-04
- Volume
- 4
- Issue
- 4
- Pages
- 325-328
- ISSN
- 2213-1779 (ISSN-L)
- OpenAlex
- W2273155798
- Cited by
- 38
- References
- 20
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 2 · 2023: 4 · 2022: 5 · 2021: 4 · 2020: 5 · 2019: 3 · 2018: 5 · 2017: 3 · 2016: 2
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- JACC Heart Failure (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Heart, Lung, and Blood Institute (R01HL127028, R01 HL107557.)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Fibrosis and Remodeling
- Keywords
- heart failure with preserved ejection fraction, inflammation, comorbidities, prevalence, clinical outcomes, heart failure with reduced ejection fraction
- MeSH terms
- Heart Failure, Humans, Inflammation, Stroke Volume, Ventricular Function, Left
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