The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Impact of New-Onset Persistent Left Bundle Branch Block on Late Clinical Outcomes in Patients Undergoing Transcatheter Aortic Valve Implantation With a Balloon-Expandable Valve
Open accessAbstract
OBJECTIVES The aim of this study was to determine the impact of new-onset persistent left bundle branch block (NOP-LBBB) on late outcomes after transcatheter aortic valve implantation (TAVI). BACKGROUND The impact of NOP-LBBB after TAVI remains controversial. METHODS A total of 668 consecutive patients who underwent TAVI with a balloon-expandable valve without pre-existing LBBB or permanent pacemaker implantation (PPI) were included. Electrocardiograms were obtained at baseline, immediately after the procedure, and daily until hospital discharge. Patients were followed at 1, 6, and 12 months and yearly thereafter. RESULTS New-onset LBBB occurred in 128 patients (19.2%) immediately after TAVI and persisted at hospital discharge in 79 patients (11.8%). At a median follow-up of 13 months (range 3 to 27 months), there were no differences in mortality rate between the NOP-LBBB and no NOP-LBBB groups (27.8% vs. 28.4%; adjusted-hazard ratio: 0.87 [95% confidence interval (CI): 0.55 to 1.37]; p = 0.54). There were no differences between groups regarding cardiovascular mortality (p = 0.82), sudden death (p = 0.87), rehospitalizations for all causes (p = 0.11), or heart failure (p = 0.55). NOP-LBBB was the only factor associated with an increased rate of PPI during the follow-up period (13.9% vs. 3.0%; hazard ratio: 4.29 [95% CI: 2.03 to 9.07], p < 0.001. NOP-LBBB was also associated with a lack of left ventricular ejection fraction improvement and poorer New York Heart Association functional class at follow-up (p < 0.02 for both). CONCLUSIONS NOP-LBBB occurred in ∼1 of 10 patients who had undergone TAVI with a balloon-expandable valve. NOP-LBBB was associated with a higher rate of PPI, a lack of improvement in left ventricular ejection fraction, and a poorer functional status, but did not increase the risk of global or cardiovascular mortality or rehospitalizations at 1-year follow-up.
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Cites
ACC/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities
Epstein, A. E., DiMarco, J. P., Ellenbogen, K. A., Estes, N. A. M., Freedman, R. A., Gettes, L. S., Gillinov, A. M., Gregoratos, G., Hammill, S. C., Hayes, D. L., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.02.032 · Cited by 2,546
Newly acquired left bundle-branch block: the framingham study
SCHNEIDER, J. F., THOMAS, H. E., KREGER, B. E., McNAMARA, P. M., & KANNEL, W. B. (1979) · Annals of Internal Medicine · doi:10.7326/0003-4819-90-3-303 · Cited by 370
Transcatheter aortic valve implantation: current and future approaches
Rodés-Cabau, J. (2012) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2011.164 · Cited by 306
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2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy
Glikson, M., Nielsen, J. C., Kronborg, M. B., Michowitz, Y., Auricchio, A., Barbash, I. M., Barrabés, J. A., Boriani, G., Braunschweig, F., Brignole, M., et al. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehab364 · Cited by 2,019
Généreux, P., Piazza, N., Alu, M. C., Nazif, T., Hahn, R. T., Pibarot, P., Bax, J. J., Leipsic, J. A., Blanke, P., Blackstone, E. H., et al. (2021) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2021.02.038 · Cited by 1,313
Self-citationVARC-3 WRITING COMMITTEE, Généreux, P., Piazza, N., Alu, M. C., Nazif, T., Hahn, R. T., Pibarot, P., Bax, J. J., Leipsic, J. A., Blanke, P., et al. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehaa799 · Cited by 915
Self-citation2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy
Glikson, M., Nielsen, J. C., Kronborg, M. B., Michowitz, Y., Auricchio, A., Barbash, I. M., Barrabés, J. A., Boriani, G., Braunschweig, F., Brignole, M., et al. (2022) · EP Europace · doi:10.1093/europace/euab232 · Cited by 914
López-Aguilera, J., Segura Saint-Gerons, J. M., Mazuelos Bellido, F., Suárez de Lezo Herreros de Tejada, J., Pineda, S. O., Pan Álvarez-Ossorio, M., Romero Moreno, M. Á., Pavlovic, D., & Suárez de Lezo Cruz Conde, J. (2016) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2016.07.057 · Cited by 17
Metadata
- Authors
- Urena, M., Webb, J. G., Cheema, A., Serra, V., Toggweiler, S., Barbanti, M., Cheung, A., Ye, J., Dumont, E., DeLarochellière, R., Doyle, D., Al Lawati, H. A., Peterson, M., Chisholm, R., Igual, A., Ribeiro, H. B., Nombela-Franco, L., Philippon, F., Garcia del Blanco, B., & Rodés-Cabau, J.
- Venue
- JACC: Cardiovascular Interventions
- Publisher
- Elsevier BV
- Published
- 2014-02
- Volume
- 7
- Issue
- 2
- Pages
- 128-136
- ISSN
- 1876-7605 (ISSN-L)
- 1936-8798
- OpenAlex
- W2062789635
- Cited by
- 171
- References
- 3
- FWCI
- 10.53
- Type
- journal article
- Language
- en
- Open access
- bronze
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- The paper
- Urena, M., Webb, J. G., Cheema, A., Serra, V., Toggweiler, S., Barbanti, M., Cheung, A., Ye, J., Dumont, E., DeLarochellière, R., Doyle, D., Al Lawati, H. A., Peterson, M., Chisholm, R., Igual, A., Ribeiro, H. B., Nombela-Franco, L., Philippon, F., Garcia del Blanco, B., & Rodés-Cabau, J. (2014). Impact of New-Onset Persistent Left Bundle Branch Block on Late Clinical Outcomes in Patients Undergoing Transcatheter Aortic Valve Implantation With a Balloon-Expandable Valve. JACC: Cardiovascular Interventions. https://doi.org/10.1016/j.jcin.2013.08.015
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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