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No clear choice between Newcastle–Ottawa Scale and Appraisal Tool for Cross-Sectional Studies to assess methodological quality in cross-sectional studies of health-related quality of life and breast cancer

Moskalewicz, Alexandra, Oremus, Mark·2020·Journal of Clinical Epidemiology

Abstract

OBJECTIVES To compare the inter-rater reliability, concurrent validity, completion time, and ease of use of two methodological quality (MQ) assessment tools for cross-sectional studies: an adapted Newcastle-Ottawa Scale (NOS) and the Appraisal Tool for Cross-Sectional Studies (AXIS). STUDY DESIGN AND SETTING Two raters applied the NOS and AXIS to 63 cross-sectional studies of health-related quality-of-life and breast cancer. RESULTS AXIS demonstrated poor inter-rater reliability (intraclass correlation coefficient [ICC] = 0.49) and required more than double the amount of time to complete compared to the NOS, which demonstrated moderate reliability (ICC = 0.73). For concurrent validity, weak and moderate positive relationships existed between NOS and AXIS (rater 1: r = 0.26; rater 2: r = 0.45). Ease of using the tools was affected by the indirectness of MQ assessments, perceived thoroughness of the tools' content, and user experience. CONCLUSION This study was the first to assess the psychometric properties of a cross-sectional NOS and AXIS. The results did not support a clear choice between selecting either tool for evaluating MQ in cross-sectional studies.

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Metadata

Authors
Moskalewicz, A., & Oremus, M.
Venue
Journal of Clinical Epidemiology
Publisher
Elsevier BV
Published
2020-04
Volume
120
Pages
94-103
ISSN
0895-4356 (ISSN-L)
OpenAlex
W2995284626
Cited by
336
References
22
FWCI
15.19
Type
journal article
Language
en
Open access
closed
Licence
  • www.elsevier.com/tdm/userlicense/1.0/ (tdm)
  • www.elsevier.com/legal/tdmrep-license (tdm)
Funders
University of Waterloo

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CoChat. (2026). Citation check: No clear choice between Newcastle–Ottawa Scale and Appraisal Tool for Cross-Sectional Studies to assess methodological quality in cross-sectional studies of health-related quality of life and breast cancer. https://app.cochat.ai/papers/10.1016/j.jclinepi.2019.12.013
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Moskalewicz, A., & Oremus, M. (2020). No clear choice between Newcastle–Ottawa Scale and Appraisal Tool for Cross-Sectional Studies to assess methodological quality in cross-sectional studies of health-related quality of life and breast cancer. Journal of Clinical Epidemiology. https://doi.org/10.1016/j.jclinepi.2019.12.013

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