The DOI matches its Crossref record; 105 of the 105 references it cites were found in a registry or an index.
Diastolic Dysfunction and Heart Failure With Preserved Ejection Fraction
Open accessAbstract
Research in the last decade has substantially advanced our understanding of the pathophysiology of heart failure with preserved ejection fraction (HFpEF). However, treatment options remain limited as clinical trials have largely failed to identify effective therapies. Part of this failure may be related to mechanistic heterogeneity. It is speculated that categorizing HFpEF patients based upon underlying pathophysiological phenotypes may represent the key next step in delivering the right therapies to the right patients. Echocardiography may provide valuable insight into both the pathophysiology and underlying phenotypes in HFpEF. Echocardiography also plays a key role in the evaluation of patients with unexplained dyspnea, where HFpEF is suspected but the diagnosis remains unknown. The combination of E/e’ and right ventricular systolic pressure has recently been shown to add independent value in the diagnostic evaluation of people suspected with HFpEF. Finally, echocardiography enables identification of different etiologies that mimic HFpEF but are treated differently, such as valvular heart disease, pericardial constriction, high output heart failure, or infiltrative myopathies such as cardiac amyloid. The purpose of this review is to summarize the current understanding of the pathophysiology and phenotyping of HFpEF with particular attention to the role of echocardiography in this context.
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A Novel Paradigm for Heart Failure With Preserved Ejection Fraction
Paulus, W. J., & Tschöpe, C. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.02.092 · Cited by 3,564
Antlanger, M., Aschauer, S., Kopecky, C., Hecking, M., Kovarik, J. J., Werzowa, J., Mascherbauer, J., Genser, B., Säemann, M. D., & Bonderman, D. (2017) · Kidney and Blood Pressure Research · doi:10.1159/000473868 · Cited by 2,808
Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction
Lam, C. S. P., Roger, V. L., Rodeheffer, R. J., Borlaug, B. A., Enders, F. T., & Redfield, M. M. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.11.051 · Cited by 1,341
Self-citationReddy, Y. N. V., Carter, R. E., Obokata, M., Redfield, M. M., & Borlaug, B. A. (2018) · Circulation · doi:10.1161/circulationaha.118.034646 · Cited by 1,278
Self-citationObokata, M., Reddy, Y. N. V., Pislaru, S. V., Melenovsky, V., & Borlaug, B. A. (2017) · Circulation · doi:10.1161/circulationaha.116.026807 · Cited by 1,179
Self-citationPhenomapping for Novel Classification of Heart Failure With Preserved Ejection Fraction
Shah, S. J., Katz, D. H., Selvaraj, S., Burke, M. A., Yancy, C. W., Gheorghiade, M., Bonow, R. O., Huang, C.-C., & Deo, R. C. (2015) · Circulation · doi:10.1161/circulationaha.114.010637 · Cited by 1,157
Exercise Hemodynamics Enhance Diagnosis of Early Heart Failure With Preserved Ejection Fraction
Borlaug, B. A., Nishimura, R. A., Sorajja, P., Lam, C. S. P., & Redfield, M. M. (2010) · Circulation: Heart Failure · doi:10.1161/circheartfailure.109.930701 · Cited by 1,118
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Cited by
Heart Failure With Preserved Ejection Fraction
Borlaug, B. A., Sharma, K., Shah, S. J., & Ho, J. E. (2023) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2023.01.049 · Cited by 742
Self-citationEvaluation and management of heart failure with preserved ejection fraction
Borlaug, B. A. (2020) · Nature Reviews Cardiology · doi:10.1038/s41569-020-0363-2 · Cited by 675
Self-citationShah, S. J., Borlaug, B. A., Kitzman, D. W., McCulloch, A. D., Blaxall, B. C., Agarwal, R., Chirinos, J. A., Collins, S., Deo, R. C., Gladwin, M. T., et al. (2020) · Circulation · doi:10.1161/circulationaha.119.041886 · Cited by 436
Obokata, M., Reddy, Y. N. V., Melenovsky, V., Sorimachi, H., Jarolim, P., & Borlaug, B. A. (2022) · European Journal of Heart Failure · doi:10.1002/ejhf.2377 · Cited by 99
Self-citationGuo, Y., Xiao, C., Zhao, K., He, Z., Liu, S., Wu, X., Shi, S., Chen, Z., & Shi, R. (2022) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000001254 · Cited by 16
Metadata
- Authors
- Obokata, M., Reddy, Y. N. V., & Borlaug, B. A.
- Venue
- JACC: Cardiovascular Imaging
- Publisher
- Elsevier BV
- Published
- 2020-01
- Volume
- 13
- Issue
- 1
- Pages
- 245-257
- ISSN
- 1876-7591 (ISSN-L)
- 1936-878X
- OpenAlex
- W2950275058
- Cited by
- 316
- References
- 105
- FWCI
- 16.30
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Obokata, M., Reddy, Y. N. V., & Borlaug, B. A. (2020). Diastolic Dysfunction and Heart Failure With Preserved Ejection Fraction. JACC: Cardiovascular Imaging. https://doi.org/10.1016/j.jcmg.2018.12.034
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