Going beyond the liver: Progress and challenges of targeted delivery of siRNA therapeutics

Cited by (283)

Items 101–200 of 283

  1. The potential of RNA-based therapy for kidney diseases
    Tjessa Bondue, Lambertus P. van den Heuvel, Elena N. Levtchenko, Roland E. Brock · 2022 · Pediatric Nephrology
  2. RNA Interference and Nanotechnology: A Promising Alliance for Next Generation Cancer Therapeutics
    Guruprasadh Swaminathan, Aisha Shigna Nadukkandy, Aviral Kumar, Vishnu Vardhan Byroju, Varsha Reddy Durgempudi, Lekha Dinesh Kumar · 2021 · Frontiers in Nanotechnology
  3. Ligand-mediated delivery of RNAi-based therapeutics for the treatment of oncological diseases
    Ahmed M Abdelaal, Andrea L. Kasinski · 2021 · NAR Cancer
  4. Conjugation of curcumin-loaded lipid nanoemulsions with cell-penetrating peptides increases their cellular uptake and enhances the anti-inflammatory effects in endothelial cells
    Viorel Simion, Daniela L Stan, Cristina Ana Constantinescu, Mariana Deleanu, Emanuel Dragan, Monica Mădălina Tucureanu, Ana‐Maria Gan, Elena Dragomir Butoi, Alina Liliana Constantin, Ileana Mânduțeanu et al. · 2016 · Journal of Pharmacy and Pharmacology
  5. Nucleic Acid Nanomedicines in Phase II/III Clinical Trials: Translation of Nucleic Acid Therapies for Reprogramming Cells
    Victoria L. M. Herrera, Aaron H. Colby, Nelson Ruiz‐Opazo, David G Coleman, Mark W. Grinstaff · 2018 · Nanomedicine
  6. TGF-β2 silencing to target biliary-derived liver diseases
    Anne Dropmann, Steven Dooley, Bedair Dewidar, Seddik Hammad, Tatjana Dediulia, Julia Werle, Vanessa Hartwig, Shahrouz Ghafoory, Stefan Wölfl, Hanna Korhonen et al. · 2020 · Gut
  7. Enhanced Lymphatic Delivery of Methotrexate Using W/O/W Nanoemulsion: In Vitro Characterization and Pharmacokinetic Study
    Ji-Hun Jang, Seung‐Hyun Jeong, Yong‐Bok Lee · 2020 · Pharmaceutics
  8. Development of Cationic Quaternary Ammonium Sulfonamide Amino Lipids for Nucleic Acid Delivery
    Jason B. Miller, Petra Kós, Victor Tieu, Kejin Zhou, Daniel J. Siegwart · 2017 · ACS Applied Materials & Interfaces
  9. Intracellular targeting with engineered proteins
    Shane Miersch, Sachdev S. Sidhu · 2016 · F1000Research
  10. Design of synthetic materials for intracellular delivery of RNAs: From siRNA-mediated gene silencing to CRISPR/Cas gene editing
    Jason B. Miller, Daniel J. Siegwart · 2018 · Nano Research
  11. Bridging small interfering RNA with giant therapeutic outcomes using nanometric liposomes
    Yuvraj Singh, Sandeep Tomar, Shariq Ali Khan, Jaya Gopal Meher, Vivek Kumar Pawar, Kavit Raval, Komal Sharma, Pankaj Kumar Singh, Mohini Chaurasia, Bathula Surendar Reddy et al. · 2015 · Journal of Controlled Release
  12. Efficient siRNA Delivery by Lipid Nanoparticles Modified with a Nonstandard Macrocyclic Peptide for EpCAM-Targeting
    Yu Sakurai, Wataru Mizumura, Manami Murata, Tomoya Hada, Shoshiro Yamamoto, Kenichiro Ito, Kazuhiro Iwasaki, Takayuki Katoh, Yuki Goto, Asako Takagi et al. · 2017 · Molecular Pharmaceutics
  13. Methotrexate-Loaded PLGA Nanoparticles: Preparation, Characterization and their Cytotoxicity Effect on Human Glioblastoma U87MG Cells
    Hassan Maleki, Farid Abedin Dorkoosh, Mahdi Adabi, Masood Khosravani, Hossein Arzani, Morteza Kamali · 2017 · International Journal of Medical Nano Research
  14. Recent Advancements in the Design of Nanodelivery Systems of siRNA for Cancer Therapy
    Dokkari Nagalaxmi Yadav, Mohammad Sadik Ali, Ajinkya Madhukar Thanekar, Sunil Venkanna Pogu, Aravind Kumar Rengan · 2022 · Molecular Pharmaceutics
  15. Modulation of the IL-6-Signaling Pathway in Liver Cells by miRNAs Targeting gp130, JAK1, and/or STAT3
    Florence Servais, Mélanie Kirchmeyer, Matthias Hamdorf, Nadège Minoungou, Stefan Rose‐John, Stephanie Kreis, Claude Haan, Iris Behrmann · 2019 · Molecular Therapy — Nucleic Acids
  16. Solid nano-in-nanoparticles for potential delivery of siRNA
    Orit Amsalem, Taher Nassar, Sandrine Benhamron, Philip Lazarovici, Simon Benita, Eylon Yavin · 2016 · Journal of Controlled Release
  17. Oral delivery of topotecan in polymeric nanoparticles: Lymphatic distribution and pharmacokinetics
    Seung‐Hyun Jeong, Ji-Hun Jang, Yong‐Bok Lee · 2021 · Journal of Controlled Release
  18. An overview of lipid constituents in lipid nanoparticle mRNA delivery systems
    Shiqi Wu, Lixin Lin, Lu Shi, Shuai Liu · 2024 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
  19. Spleen selective enhancement of transfection activities of plasmid DNA driven by octaarginine and an ionizable lipid and its implications for cancer immunization
    Seigo Kimura, Ikramy A. Khalil, Yaser Hosny Ali Elewa, Hideyoshi Harashima · 2019 · Journal of Controlled Release
  20. Polymeric Nanoparticles Based on Tyrosine-Modified, Low Molecular Weight Polyethylenimines for siRNA Delivery
    Alexander Ewe, Sandra Noske, Michael Karimov, Achim Michael Aigner · 2019 · Pharmaceutics
  21. Development of amino acid-modified biodegradable lipid nanoparticles for siRNA delivery
    Pratikkumar Patel, John Fetse, Chien‐Yu Lin, Yuhan Guo, Md Reaid Hasan, Maryam Nakhjiri, Zhen Zhao, Akshay Jain, Kun Cheng · 2022 · Acta Biomaterialia
  22. Silencing the roadblocks to effective triple-negative breast cancer treatments by siRNA nanoparticles
    Jenny G. Parvani, Mark W. Jackson · 2017 · Endocrine Related Cancer
  23. Formulation of biocompatible targeted ECO/siRNA nanoparticles with long-term stability for clinical translation of RNAi
    Ayat, Nadia R., Sun, Zhanhu, Sun, Da, Yin, Michelle, Hall, Ryan C., Vaidya, Amita M., Liu, Xujie, Schilb, Andrew L., Scheidt, Josef H., Lu, Zheng-Rong · 2019 · Nucleic Acid Therapeutics
  24. Spleen-targeted nanosystems for immunomodulation
    Fazhan Wang, Jia Lou, Xiaoke Gao, Lijing Zhang, Feifei Sun, Zhaoqing Wang, Tianjiao Ji, Zhihai Qin · 2023 · Nano Today
  25. Enhancing siRNA cancer therapy: Multifaceted strategies with lipid and polymer-based carrier systems
    Nazgol Karimi Dastgerdi, Nazanin Karimi Dastgerdi, Hulya Bayraktutan, Gabriella Costabile, Fatemeh Atyabi, Rassoul Dinarvand, Giuseppe Longobardi, Cameron Alexander, Claudia Conte · 2024 · International Journal of Pharmaceutics
  26. Synthesis of multifunctional bovine serum albumin microcapsules by the sonochemical method for targeted drug delivery and controlled drug release
    Zhanfeng Li, Fengzhi Xu, Quanshun Li, Songfeng Liu, Hongyan Wang, Helmuth Möhwald, Xuejun Cui · 2015 · Colloids and Surfaces B Biointerfaces
  27. Therapeutic Oligonucleotides Targeting Liver Disease: TTR Amyloidosis
    Christoph Niemietz, Gursimran Chandhok, Hartmut Schmidt · 2015 · Molecules
  28. Increased Bone Marrow Uptake and Accumulation of Very-Late Antigen-4 Targeted Lipid Nanoparticles
    Laura E. Swart, Marcel H.A.M. Fens, Anita van Oort, Piotr Waranecki, L. Daniel Mata Casimiro, D Tuk, Martijn Hendriksen, Luca M. van den Brink, Elizabeth K. Schweighart, Cor W. Seinen et al. · 2023 · Pharmaceutics
  29. Engineering a biomimetic system for hepatocyte-specific RNAi treatment of non-alcoholic fatty liver disease
    Xuan He, Zhimin Chang, Fangman Chen, Wensheng Zhang, Madi Sun, Tongfei Shi, Jie Liu, Peiyu Chen, Kunbao Zhang, Shan Guan et al. · 2023 · Acta Biomaterialia
  30. GalNac-siRNA conjugate delivery technology promotes the treatment of typical chronic liver diseases
    Qin, Zhen-Xin, Zuo, Ling, Zeng, Ziran, Ma, Rongguan, Xie, Wenyan, Zhu, Xiao, Zhou, Xiaorong · 2025 · Expert Opinion on Drug Delivery
  31. Inhibition of hepatitis C virus in mouse models by lipidoid nanoparticle-mediated systemic delivery of siRNA against PRK2
    Jae-Su Moon, Seung‐Hoon Lee, Song-Hee Han, Eun‐Jung Kim, Hee Cho, Wooseong Lee, Mi Kyung Kim, Tae-Eun Kim, Hyun‐Ji Park, Jin‐Kyu Rhee et al. · 2016 · Nanomedicine Nanotechnology Biology and Medicine
  32. Post-PEGylation of siRNA Lipo-oligoamino Amide Polyplexes Using Tetra-glutamylated Folic Acid as Ligand for Receptor-Targeted Delivery
    Katharina Müller, Eva Kessel, Philipp Michael Klein, Miriam Höhn, Ernst Wagner · 2016 · Molecular Pharmaceutics
  33. Fatty Acid Synthase (FASN) siRNA-Encapsulated-Her-2 Targeted Fab’-Immunoliposomes for Gene Silencing in Breast Cancer Cells
    Arif Khan, Ahmed N. Aljarbou, Yousef Homood Aldebasi, Khaled SA Allemeilam, Mohammad A Alsahly, Shamshir Khan, Abdulmohsen M. Alruwetei, Masood Alam Khan · 2020 · International Journal of Nanomedicine
  34. Design and Synthesis of Piperazine-Based Compounds Conjugated to Humanized Ferritin as Delivery System of siRNA in Cancer Cells
    Natalia Pediconi, Francesca Ghirga, Cristina Del Plato, Giovanna Peruzzi, Constantinos M. Athanassopoulos, Mattia Mori, Maria Elisa Crestoni, Davide Corinti, Franco Ugozzoli, Chiara Massera et al. · 2021 · Bioconjugate Chemistry
  35. Dual stimulus of hyperthermia and intracellular redox environment triggered release of siRNA for tumor-specific therapy
    Yanfang Yang, Yang� Yang, Xiangyang Xie, Xueqing Xu, Xuejun Xia, Hongliang Wang, Lin Li, Wujun Dong, Panpan Ma, Yuling Liu · 2016 · International Journal of Pharmaceutics
  36. Optimal Hydrophobicity in Ring-Opening Metathesis Polymerization-Based Protein Mimics Required for siRNA Internalization
    Brittany M. deRonde, Nicholas Dunn Posey, Ronja Otter, Leah M. Caffrey, Lisa M. Minter, Gregory N. Tew · 2016 · Biomacromolecules
  37. siRNA therapeutics: insights, challenges, remedies and future prospects
    Saba Khan, Urushi Rehman, Neha Parveen, Shobhit Kumar, Sanjula Baboota, Javed Ali · 2023 · Expert Opinion on Drug Delivery
  38. Nucleic acid combinations: A new frontier for cancer treatment
    Remant Bahadur K.C., Bindu Thapa, Juliana Valencia‐Serna, Hamidreza Montezari Aliabadi, Hasan Uludağ · 2017 · Journal of Controlled Release
  39. The notorious R.N.A. in the spotlight - drug or target for the treatment of disease
    Philipp Reautschnig, Paul Vogel, Thorsten Stafforst · 2016 · RNA Biology
  40. Reversal of multidrug resistance in breast cancer MCF-7/ADR cells by h-R3-siMDR1-PAMAM complexes
    Jun Li, Jing Liu, Nana Guo, Xiaoning Zhang · 2016 · International Journal of Pharmaceutics
  41. Tyrosine-Modification of Polypropylenimine (PPI) and Polyethylenimine (PEI) Strongly Improves Efficacy of siRNA-Mediated Gene Knockdown
    Sandra Noske, Michael Karimov, Achim Michael Aigner, Alexander Ewe · 2020 · Nanomaterials
  42. Liver‐directed drugs for t ransthyretin‐mediated amyloidosis
    Thomas H. Brannagan, John L. Berk, Julian David Gillmore, Mathew S. Maurer, Márcia Waddington‐Cruz, Marianna Fontana, Ahmad Masri, Laura Piera Obici, Michela Brambatti, Brenda F. Baker et al. · 2022 · Journal of the Peripheral Nervous System
  43. Conjugates of small targeting molecules to non-viral vectors for the mediation of siRNA
    Defu Zhi, Yinan Zhao, Shaohui Cui, Huiying Chen, Shubiao Zhang · 2016 · Acta Biomaterialia
  44. Therapeutic Oligonucleotides with Polyethylene Glycol Modifications
    Johannes Winkler · 2015 · Future Medicinal Chemistry
  45. Nano-carriers for drug routeing – towards a new era
    Lakkireddy Harivardhan Reddy, Didier Bazile · 2018 · Journal of drug targeting
  46. Long-term safety and efficacy of fitusiran prophylaxis, and perioperative management, in people with hemophilia A or B
    Steven W. Pipe, Toshko Jelev Lissitchkov, Pencho Georgiev, Sarah Mangles, Inga Hegemann, Alice Trinchero, Pratima Chowdary, Adam Forbes, Liqi Feng, Laurel A. Menapace et al. · 2024 · Blood Advances
  47. The Yin and Yang of nucleic acid-based therapy in the brain
    Stefano Gustincich, Silvia Zucchelli, Antonello Mallamaci · 2016 · Progress in Neurobiology
  48. Liposome mediated-CYP1A1 gene silencing nanomedicine prepared using lipid film-coated proliposomes as a potential treatment strategy of lung cancer
    Mengtian Zhang, Qin Lin Wang, Ka‐Wai Wan, Waqar Ahmed, David Andrew Phoenix, Zhirong Zhang, Mohamed A. Elrayess, Abdelbary M. A. Elhissi, Xun Sun · 2019 · International Journal of Pharmaceutics
  49. Current development of targeted oligonucleotide-based cancer therapies: Perspective on HER2-positive breast cancer treatment
    Worapol Ngamcherdtrakul, David J. Castro, Shenda Gu, Jingga Morry, Moataz M. Reda, Joe W. Gray, Wassana Yantasee · 2016 · Cancer Treatment Reviews
  50. Preparation of siRNA encapsulated nanoliposomes suitable for siRNA delivery by simply discontinuous mixing
    Amir Abbas Mokhtarieh, Ji‐Eun Lee, Semi Kim, Myung Kyu Lee · 2018 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  51. Current drugs in early development for treating hepatitis C virus-related hepatic fibrosis
    Jerzy Jaroszewicz, Marta Flisiak‐Jackiewicz, Dariusz Marek Lebensztejn, Robert Flisiak · 2015 · Expert Opinion on Investigational Drugs
  52. Cholecystokinin Receptor-Targeted Polyplex Nanoparticle Inhibits Growth and Metastasis of Pancreatic Cancer
    Julian Burks, Sandeep Nadella, Abdullah Mahmud, Charoen Mankongpaisarnrung, Juan Wang, Jong‐in Hahm, Robin D. Tucker, Narayan Shivapurkar, Stęphan T. Stern, Jill Palmer Smith · 2018 · Cellular and Molecular Gastroenterology and Hepatology
  53. Recent advances in the liposomal nanovesicles based immunotherapy in the treatment of cancer: A review
    Yahya Alhamhoom, Greeshma Kakinani, Mohamed Rahamathulla, Riyaz Ali M. Osmani, Umme Hani, Kamal Y. Thajudeen, G. Kiran Raj, D. V. Gowda · 2022 · Saudi Pharmaceutical Journal
  54. Clinical potential of oligonucleotide-based therapeutics in the respiratory system
    Sterghios Athanasios Moschos, Louise Usher, Mark A. Lindsay · 2016 · Pharmacology & Therapeutics
  55. Autologous Cancer Cell-Derived Extracellular Vesicles as Drug-Delivery Systems: A Systematic Review of Preclinical and Clinical Findings and Translational Implications
    Yongjiang Li, Junyong Wu, Xiong-Bin Hu, Jiemin Wang, Daxiong Xiang · 2019 · Nanomedicine
  56. Virus Mimetic Shell-Sheddable Chitosan Micelles for siVEGF Delivery and FRET-Traceable Acid-Triggered Release
    Shengyu Zhang, Ye Hua Gan, Lanlan Shao, Tianqing Liu, Danyi Wei, Yanyan Yu, Hongwei Guo, Hongyan Zhu · 2020 · ACS Applied Materials & Interfaces
  57. The Length of Hydrophobic Chain in Amphiphilic Polypeptides Regulates the Efficiency of Gene Delivery
    Ying Zhang, Zhiping Zhou, Mingsheng Chen · 2018 · Polymers
  58. Inhibition of HIV replication through siRNA carried by CXCR4-targeted chimeric nanobody
    Catarina Cunha-Santos, Pedro R.L. Perdigão, Francisco Martin, Joana Gomes Oliveira, Miguel Gomes Cardoso, Ana M. Manuel, Nuno Taveira, João Gonçalves · 2019 · Cellular and Molecular Life Sciences
  59. Modifying internal organization and surface morphology of siRNA lipoplexes by sodium alginate addition for efficient siRNA delivery
    Danielle Campiol Arruda, Ismael González, Stéphanie Finet, Luis A. Córdova, Valérie Trichet, Gracielle Ferreira Andrade, Céline Hoffmann, Pascal Bigey, W. A. A. Macedo, Armando Silva‐Cunha et al. · 2019 · Journal of Colloid and Interface Science
  60. Controlled Release of RNAi Molecules by Tunable Supramolecular Hydrogel Carriers
    Maarten H. Bakker, Eva van Rooij, Patricia Y. W. Dankers · 2018 · Chemistry - An Asian Journal
  61. Advantages and challenges in nanomedicines for chronic liver diseases: A hepatologist's perspectives
    Devaraj Ezhilarasan · 2021 · European Journal of Pharmacology
  62. Evaluation of Therapeutic Oligonucleotides for Familial Amyloid Polyneuropathy in Patient-Derived Hepatocyte-Like Cells
    Christoph Niemietz, Vanessa Sauer, Jacqueline Stella, Lutz Fleischhauer, Gursimran Chandhok, Sarah Guttmann, Yesim Avsar, Shuling Guo, Elizabeth J. Ackermann, Jared Gollob et al. · 2016 · PLoS ONE
  63. Recent advances in the targeting of systemically administered non-viral gene delivery systems
    Ikramy A. Khalil, Yusuke Sato, Hideyoshi Harashima · 2019 · Expert Opinion on Drug Delivery
  64. Two Principles for Polymersomes with Ultrahigh Biomacromolecular Loading Efficiencies: Acid-Induced Adsorption and Affinity-Enhanced Attraction
    Shuai Chen, Jianglei Qin, Jianzhong Du · 2020 · Macromolecules
  65. Barcoding chemical modifications into nucleic acids improves drug stability in vivo
    Cory D. Sago, Sujay Kalathoor, Jordan P. Fitzgerald, Gwyneth N. Lando, Naima Djeddar, Anton V. Bryksin, James E. Dahlman · 2018 · Journal of Materials Chemistry B
  66. Stealth-Engineered Albumin-Coated Nanoparticles for Targeted Therapy: Effective Drug Delivery and Tumor Suppression in Xenograft-Zebrafish Model
    Sara Bozzer, Maria Cristina Grimaldi, Luca De Maso, Marcello Manfredi, Giuseppe Toffoli, Michele Dal Bo, Daniele Sblattero, Paolo Macor · 2024 · International Journal of Nanomedicine
  67. Neutrophil-like cell membrane-coated metal-organic frameworks for siRNA delivery targeting NOX4 to alleviate oxidative stress in acute ischemic injury
    Min Wang, Yunbo Wang, Pengqi Zhang, Chenjie Gu, Xianlei Zhao, Xinghan Gong, Xiaohang Yang, Jianwei Pan, Yongmei Xi · 2025 · Acta Biomaterialia
  68. Delivery of gene targeting siRNAs to breast cancer cells using a multifunctional peptide complex that promotes both targeted delivery and endosomal release
    Jeffrey D. Bjorge, Andy Pang, Donald J. Fujita · 2017 · PLoS ONE
  69. HER2/neu Oncogene Silencing in a Breast Cancer Cell Model Using Cationic Lipid-Based Delivery Systems
    Adhika Balgobind, Aliscia Nicole Daniels, Mario Ariatti, Moganavelli Singh · 2023 · Pharmaceutics
  70. A review of RNA nanoparticles for drug/gene/protein delivery in advanced therapies: Current state and future prospects
    Pegah Vosoughi, Seyed Morteza Naghib, Babak Mikaeeli Kangarshahi, Mohammad Reza Mozafari · 2025 · International Journal of Biological Macromolecules
  71. Development of bioactive materials for glioblastoma therapy
    Jun Yang, Yan Li, Tianlu Zhang, Xin Zhang · 2016 · Bioactive Materials
  72. Sustained delivery of siRNA poly- and lipopolyplexes from porous macromer-crosslinked gelatin gels
    Katharina Schwabe, Alexander Ewe, C. Kohn, Tina Loth, Achim Michael Aigner, Michael Christian Hacker, Michaela Schulz‐Siegmund · 2017 · International Journal of Pharmaceutics
  73. Beyond GalNAc! Drug delivery systems comprising complex oligosaccharides for targeted use of nucleic acid therapeutics
    Joseph O'Sullivan, José Muñoz-Muñoz, Graeme Turnbull, Neil Sim, Stuart Penny, Sterghios Athanasios Moschos · 2022 · RSC Advances
  74. Nucleic acid delivery by lipid nanoparticles for organ targeting
    Jialin Guo, Mingrui Gu, Yahui Chen, Tao Xiong, Yiyang Zhang, Simin Chen, Mingle Li, Xiaoqiang Chen, Xiaojun Peng · 2025 · Chinese Chemical Letters
  75. ADVANCES IN LIPOSOMAL DRUG DELIVERY SYSTEM: FASCINATING TYPES AND POTENTIAL APPLICATIONS
    Smita Bonde, Sukanya Nair · 2017 · International Journal of Applied Pharmaceutics
  76. Amphiphilic poly(α)glutamate polymeric micelles for systemic administration of siRNA to tumors
    Adva Krivitsky, Dina Polyak, Anna Scomparin, Shay Eliyahu, Paula Ofek, Galia Tiram, Hagar Kalinski, Sharon Avkin-Nachum, Natàlia Feiner‐Gracia, Lorenzo Albertazzi et al. · 2017 · Nanomedicine Nanotechnology Biology and Medicine
  77. Lipid-based Vehicles for siRNA Delivery in Biomedical Field
    Tianzhong Li, Linfeng Huang, Mengsu Yang · 2019 · Current Pharmaceutical Biotechnology
  78. Nanocarriers as a Delivery Platform for Anticancer Treatment: Biological Limits and Perspectives in B-Cell Malignancies
    Sara Bozzer, Michele Dal Bo, Maria Cristina Grimaldi, Giuseppe Toffoli, Paolo Macor · 2022 · Pharmaceutics
  79. Enhanced Targeted Delivery of Minocycline via Transferrin Conjugated Albumin Nanoparticle Improves Neuroprotection in a Blast Traumatic Brain Injury Model
    Venkatesan Perumal, Arun Reddy Ravula, Agnieszka Agas, Aakaash Gosain, Aswati Aravind, Ponnurengam Malliappan Sivakumar, Shanmuga Sundari, Karthik Sambath, Sivakumar Vijayaraghavalu, Namas Chandra · 2023 · Brain Sciences
  80. CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors
    Khalil Ahmed, Betsy T. Kren, Md. Joynal Abedin, Rachel Isaksson Vogel, Daniel P. Shaughnessy, Lucas P. Nacusi, Vicci L. Korman, Yingming Li, Scott M. Dehm, Cheryl L. Zimmerman et al. · 2016 · Oncotarget
  81. Aptamers as the chaperones (Aptachaperones) of drugs-from siRNAs to DNA nanorobots
    Marimuthu Citartan, Harleen Kaur, Ravinderan Presela, Thean‐Hock Tang · 2019 · International Journal of Pharmaceutics
  82. Defective Ribonucleoproteins, Mistakes in RNA Processing, and Diseases
    Mia K. Mihailovic, Angela Chen, Juan C. Gonzalez‐Rivera, Lydia M. Contreras · 2017 · Biochemistry
  83. “Clicking” Gene Therapeutics: A Successful Union of Chemistry and Biomedicine for New Solutions
    Kira Astakhova, Roslyn Michelle Ray, Maria Taskova, Jesper Uhd, Annika Carstens, Kevin V. Morris · 2018 · Molecular Pharmaceutics
  84. Targeted delivery and endosomal cellular uptake of DARPin-siRNA bioconjugates: Influence of linker stability on gene silencing
    Cornelia Lorenzer, Sonja Streußnig, Emilia Tot, Anna-Maria Winkler, Hannes Merten, Fabian Brandl, Edward John Sayers, Peter Watson, Arwyn Tomos Jones, Uwe Zangemeister‐Wittke et al. · 2019 · European Journal of Pharmaceutics and Biopharmaceutics
  85. Structure–Function Correlation of Aminated Poly(α)glutamate as siRNA Nanocarriers
    Adva Krivitsky, Dina Polyak, Anna Scomparin, Shay Eliyahu, Asaf Ori, Sharon Avkin-Nachum, Vadim Krivitsky, Ronit Satchi‐Fainaro · 2016 · Biomacromolecules
  86. Protein is expressed in all major organs after intravenous infusion of mRNA-lipid nanoparticles in swine
    Francesca Ferraresso, Katherine E. Badior, Monica S Seadler, Youjie Zhang, Amanda Wietrzny, Massimo F. Cau, Amber Haugen, Geoffrey G. Rodriguez, Mitchell Dyer, Pieter R. Cullis et al. · 2024 · Molecular Therapy — Methods & Clinical Development
  87. RNA interference to enhance radiation therapy: Targeting the DNA damage response
    Gishan Ratnayake, Amanda Louise Bain, Nicholas L. Fletcher, Christopher B. Howard, Kum Kum Khanna, Kristofer J. Thurecht · 2018 · Cancer Letters
  88. A siRNA mediated hepatic dpp4 knockdown affects lipid, but not glucose metabolism in diabetic mice
    Sven Wolfgang Görgens, Kerstin Jahn‐Hofmann, Dinesh S. Bangari, Sheila Cummings, Christiane Metz-Weidmann, Uwe Schwahn, Paulus Wohlfart, Matthias Schäfer, Maximilian Bielohuby · 2019 · PLoS ONE
  89. Nanoparticles-Based Oligonucleotides Delivery in Cancer: Role of Zebrafish as Animal Model
    Sara Bozzer, Michele Dal Bo, Giuseppe Toffoli, Paolo Macor, Sara Capolla · 2021 · Pharmaceutics
  90. Stability Criterion for the Assembly of Core–Shell Lipid–Polymer–Nucleic Acid Nanoparticles
    Juan Luis Paris, Ricardo Gaspar, Filipe Coelho, Pieter De Beule, Bruno F. B. Silva · 2023 · ACS Nano
  91. Click modified amphiphilic graft copolymeric micelles of poly(styrene-alt-maleic anhydride) for combinatorial delivery of doxorubicin and plk-1 siRNA in cancer therapy
    M. R. Aji Alex, Srivani Veeranarayanan, Aby Cheruvathoor Poulose, Chetan Nehate, D. Sakthi Kumar, Veena Koul · 2016 · Journal of Materials Chemistry B
  92. What Can RNA-Based Therapy Do for Monogenic Diseases?
    Luka A. Clarke, Margarida Duarte Amaral · 2023 · Pharmaceutics
  93. Concise Postsynthetic Preparation of Oligonucleotide–Oligopeptide Conjugates Through Facile Disulfide Bond Formation
    Mehrdad Dirin, Ernst Urban, Bodo Lachmann, Christian R. Noe, Johannes Winkler · 2015 · Future Medicinal Chemistry
  94. Fentanyl Initiated Polymers Prepared by ATRP for Targeted Delivery
    Devora Cohen-Karni, Marina Kovaliov, Shaohua Li, Stephen Jaffee, Nestor Denys Tomycz, Saadyah E. Averick · 2017 · Bioconjugate Chemistry
  95. Armamentarium of nanoscaled lipid drug delivery systems customized for oral administration: In silico docking patronage, absorption phenomenon, preclinical status, clinical status and future prospects
    Ashish Baldi, Monika Chaudhary, Sheshank Sethi, Abhiav, Ramesh Chandra, Jitender Madan · 2018 · Colloids and Surfaces B Biointerfaces
  96. shRNAs Targeting a Common KCNQ1 Variant Could Alleviate Long-QT1 Disease Severity by Inhibiting a Mutant Allele
    Lucía Cócera Ortega, Ronald Wilders, Selina C. Kamps, Benedetta Fabrizi, Irit Huber, Ingeborg van der Made, Anouk van den Bout, Dylan K. de Vries, Lior Gepstein, Arie O. Verkerk et al. · 2022 · International Journal of Molecular Sciences
  97. SPIONs’ Enhancer Effect on Cell Transfection: An Unexpected Advantage for an Improved Gene Delivery System
    Laura Balcells Garcia, Cristina Fornaguera, Pau Brugada-Vilà, Marta Guerra‐Rebollo, Óscar Meca‐Cortés, Gema Martı́nez, Núria Rubio, Jerónimo Blanco, Jesús Santamarı́a, Anna Cascante et al. · 2019 · ACS Omega
  98. Fragment-based solid-phase assembly of oligonucleotide conjugates with peptide and polyethylene glycol ligands
    Mehrdad Dirin, Ernst Urban, Christian R. Noe, Johannes Winkler · 2016 · European Journal of Medicinal Chemistry
  99. Applications and challenges of biomaterial mediated mRNA delivery
    Huapan Fang, Qian Chen · 2022 · Exploration of Targeted Anti-tumor Therapy
  100. Carrier-free Gene Silencing by Amphiphilic Nucleic Acid Conjugates in Differentiated Intestinal Cells
    Elena Moroz, Lee Soo Hyeon, Ken Yamada, François Halloy, Saúl Martínez‐Montero, Hartmut Jahns, Jonathan Hall, Masad José Damha, Bastien Castagner, Jean‐Christophe Leroux · 2016 · Molecular Therapy — Nucleic Acids