The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Drug delivery challenges and future of chemotherapeutic nanomedicine for glioblastoma treatment
Abstract
ABSTRACT Glioblastoma (GBM) is one of the most aggressive and deadliest central nervous system tumors, and the current standard treatment is surgery followed by radiotherapy with concurrent chemotherapy. Nevertheless, the survival period is notably low. Although ample research has been performed to develop an effective therapeutic strategy for treating GBM, the success of extending patients’ survival period and quality of life is limited. This review focuses on the strategies developed to address the challenges associated with drug delivery in GBM, particularly nanomedicine. The first part describes major obstacles to the development of effective GBM treatment strategies. The second part focuses on the conventional chemotherapeutic nanomedicine strategies, their limitations and the novel and advanced strategies of nanomedicine, which could be promising for GBM treatment. We also highlighted the prominence of nanomedicine clinical translation. The near future looks bright following the beginning of clinical translation of nanochemotherapy for GBM.
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Cites
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Zhao, M., van Straten, D., Broekman, M. L. D., Préat, V., & Schiffelers, R. M. (2020) · Theranostics · doi:10.7150/thno.38147 · Cited by 373
Self-citationAgarose-based biomaterials for advanced drug delivery
Khodadadi Yazdi, M., Taghizadeh, A., Taghizadeh, M., Stadler, F. J., Farokhi, M., Mottaghitalab, F., Zarrintaj, P., Ramsey, J. D., Seidi, F., Saeb, M. R., et al. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.07.028 · Cited by 268
Tumor Cell Infiltration into the Brain in Glioblastoma: From Mechanisms to Clinical Perspectives
Seker-Polat, F., Pinarbasi Degirmenci, N., Solaroglu, I., & Bagci-Onder, T. (2022) · Cancers · doi:10.3390/cancers14020443 · Cited by 253
Zou, Y., Liu, Y., Yang, Z., Zhang, D., Lu, Y., Zheng, M., Xue, X., Geng, J., Chung, R., & Shi, B. (2018) · Advanced Materials · doi:10.1002/adma.201803717 · Cited by 203
Nexus between in silico and in vivo models to enhance clinical translation of nanomedicine
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Metadata
- Authors
- Ganipineni, L. P., Danhier, F., & Préat, V.
- Venue
- Journal of Controlled Release
- Publisher
- Elsevier BV
- Published
- 2018-07
- Volume
- 281
- Pages
- 42-57
- ISSN
- 0168-3659 (ISSN-L)
- OpenAlex
- W2803361339
- Cited by
- 217
- References
- 12
- FWCI
- 6.31
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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