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Medication reconciliation: a practical tool to reduce the risk of medication errors
Abstract
Preventable adverse drug events are associated with one out of five injuries or deaths. Estimates reveal that 46% of medication errors occur on admission or discharge from a clinical unit/hospital when patient orders are written. This study was performed to reduce medication errors in patient's discharge orders through a reconciliation process in an adult surgical intensive care unit (ICU). A discharge survey was implemented as part of the medication reconciliation process. The admitting nurse initiated the survey within 24 hours of ICU admission and the charge nurse completed the survey on discharge. Baseline data were obtained through a random sampling of 10% of discharges in first 2 weeks of the study (July 2001-May 2002). Medical and anesthesia records were reviewed, allergies and home medications verified with patient/family and findings compared with orders at time of ICU discharge. Baseline data revealed that 31 of 33 (94%) patients had orders changed. By week 24, nearly all medication errors in discharge orders were eliminated. In conclusion, use of the discharge survey in this medication reconciliation process resulted in a dramatic drop in medications errors for patients discharged from an ICU. The survey is now a part of our electronic medical record and used in 4 adult ICUs and 2 medicine floors.
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“In 2017, a single center before and after study reported shorter duration of vasopressor therapy and lower mortality following the administration of combination of high dose vitamin C, hydrocortisone, and thiamine to patients with sepsis and septic shock (521).”
From Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. (2021) · cites this paper as [521]
In the citing paper
“Medication reconciliation has been associated with fewer medication errors [598, 612] and may help reduce hospital readmission [613, 614].”
From Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 (2021) · cites this paper as [612]
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“(CPOE) systems, often in combination with clinical decision support systems (CDSS), the addition of (clinical) pharmacists to medical teams, and the introduction of medication reconciliation at hospital admission and discharge.(6,7,10,11) Although some of these interventions”
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BackgroundMedication Reconciliation Effect on Prolonged Inpatient Stress Ulcer Prophylaxis
Zeigler, A. J., McAllen, K. J., Slot, M. G., & Barletta, J. F. (2008) · Annals of Pharmacotherapy · doi:10.1345/aph.1l123 · Cited by 26
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“The process of verifying medication use, identifying variances, and rectifying medication errors at interfaces of care is called ‘‘medication reconciliation’’(1); by this process, doctors obtain the most accurate list of their patient’s medications, which is crucial for patient safety.(2) Previous studies showed that…”
Medication Reconciliation: Developing and Implementing a Program
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“As shown by Pronovost et al. [ 30 ], error reduction can be achieved with a medication reconciliation process.”
BackgroundLesselroth, B., Adams, K. A., Church, V., Tallett, S., Russ, Y., Wiedrick, J. T., Forsberg, C. W., & Dorr, D. A. (2018) · Applied Clinical Informatics · doi:10.1055/s-0038-1645889 · Cited by 14
Vital signs 2015: The state of safety and quality in Australian health care
Simmonds, F. D., & Alexander, T. L. (2015) · Research Online (University of Wollongong) · Cited by 14
From Hospital to Home Healthcare
BRUNING, K., & Selder, F. E. (2011) · Home Healthcare Now · doi:10.1097/nhh.0b013e3182079893 · Cited by 13
“The instrument was developed specifically for this study because other instruments reported in the literature were oriented to inpatient use (Ketchum et al., 2005; Pronovost et al., 2003; Rodehaver & Fearing, 2005; Rogers et al., 2006; Rozich et al., 2004) and have limited utility for home healthcare application.”
MethodPharmacy–nursing intervention to improve accuracy and completeness of medication histories
Tessier, E. G., Henneman, E. A., Nathanson, B. H., Plotkin, K., & Heelon, M. W. (2010) · American Journal of Health-System Pharmacy · doi:10.2146/ajhp090104 · Cited by 13
Value of Medication Reconciliation in Reducing Medication Errors on Admission to Hospital
McLeod, S., Lum, E., & Mitchell, C. (2008) · Journal of Pharmacy Practice and Research · doi:10.1002/j.2055-2335.2008.tb00837.x · Cited by 13
Electronic health records in nursing from 2000 to 2020: A bibliometric analysis
Luan, Z., Zhang, Z., Gao, Y., Du, S.-Y., Wu, N., Chen, Y., & Peng, X. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1049411 · Cited by 13
Johnson, K., Burkett, G. S., Nelson, D., Chen, A. R., Matlin, C., Garger, C., McMahan, S., Hughes, H., Miller, M. R., & Kim, J. M. (2018) · Pediatric Quality and Safety · doi:10.1097/pq9.0000000000000109 · Cited by 12
Anazi, A. A. (2021) · Health Informatics Journal · doi:10.1177/1460458220987276 · Cited by 12
A Multiple Baseline Trial of an Electronic ICU Discharge Summary Tool for Improving Quality of Care*
Stelfox, H. T., Brundin‐Mather, R., Soo, A., Whalen-Browne, L., Kashyap, D., Sauro, K. M., Bagshaw, S. M., Fiest, K. M., Taljaard, M., & Leigh, J. P. (2022) · Critical Care Medicine · doi:10.1097/ccm.0000000000005638 · Cited by 12
Role of Transitional Care Measures in the Prevention of Readmission After Critical Illness
Peters, J. S. (2017) · Critical Care Nurse · doi:10.4037/ccn2017218 · Cited by 15
Bosma, B. E., Meuwese, E., Tan, S. S., van Bommel, J., Melief, P. H. G. J., Hunfeld, N., & van den Bemt, P. M. L. A. (2017) · BMC Health Services Research · doi:10.1186/s12913-017-2065-y · Cited by 12
Karamchandani, K., Schoaps, R. S., Bonavia, A. S., Prasad, A., Quintili, A., Lehman, E. B., & Carr, Z. J. (2018) · Therapeutic Advances in Drug Safety · doi:10.1177/2042098618809933 · Cited by 14
Botros, S., & Dunn, J. D. (2019) · BMJ Open Quality · doi:10.1136/bmjoq-2018-000363 · Cited by 12
“This process is based on the safety principle of independent redundancies—having independent checks, generally by different providers, for key steps in the process.(14)”
BackgroundBoockvar, K. S., Koufacos, N. S., May, J., Schwartzkopf, A. L., Guerrero, V. M., Judon, K. M., Schubert, C. C., Franzosa, E. C., & Dixon, B. E. (2022) · Journal of General Internal Medicine · doi:10.1007/s11606-022-07397-5 · Cited by 12
Simulation Modeling of a Check‐in and Medication Reconciliation Ambulatory Clinic Kiosk
Lesselroth, B., Eisenhauer, W. D., Adams, S., Dorr, D. A., Randall, C., Channon, P., Adams, K., Church, V., Felder, R. S., & Douglas, D. (2011) · Journal of Healthcare Engineering · doi:10.1260/2040-2295.2.2.197 · Cited by 12
“These errors are often associated with system-based weaknesses at interfaces-in-care and are caused by discontinuity in providers, information gaps, and changes in patient health status [4-9].”
BackgroundGao, L., Han, Y., Jia, Z., Wang, P., Zhang, M., Ma, T., Yan, S., & Liu, H. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1249636 · Cited by 11
Johnsgård, T., Elenjord, R., Holis, R. V., Waaseth, M., Zahl-Holmstad, B., Fagerli, M., Svendsen, K., Lehnbom, E. C., Ofstad, E. H., Risør, T., et al. (2024) · BMC Emergency Medicine · doi:10.1186/s12873-024-00974-3 · Cited by 11
“Early identification of medication errors and medication-related problems through tasks like MedRec and medication review can prevent hospitalization, reduce length of stay and improve therapy [12, 13].”
BackgroundBuhl, A., Augustine, J. M., Taylor, A. M., Martin, R., & Warholak, T. L. (2017) · Journal of Managed Care & Specialty Pharmacy · doi:10.18553/jmcp.2017.23.3.388 · Cited by 11
A Prospective Study on Medication Errors in an Intensive Care Unit
Moudgil, K., Bhagya, P., Shaji, J. R., SACHIN, I., & PIYARI, S. (2020) · Turkish Journal of Pharmaceutical Sciences · doi:10.4274/tjps.galenos.2020.95825 · Cited by 11
Capture and Documentation of Coded Data on Adverse Drug Reactions: An Overview
Paul, L. J., & Robinson, K. M. (2012) · Health Information Management Journal · doi:10.1177/183335831204100304 · Cited by 11
“pdf Medication reconciliation is an important ‘practice tool’ for reducing medication errors in intensive care units (Pronovost et al. 2003), tertiary settings (Kramer et al.”
BackgroundMedication Reconciliation: Work Domain Ontology, prototype development, and a predictive model.
Markowitz, E., Bernstam, E. V., Herskovic, J. R., Zhang, J., Shneiderman, B., Catherine Plaisant, B., & Johnson, T. R. (2011) · PubMed Central · Cited by 11
Effectiveness of strategies to promote safe transition of elderly people across care settings
Mansah, M., Fernandez, R. S., Griffiths, R., & Chang, E. M. L. (2009) · JBI Library of Systematic Reviews · doi:10.11124/jbisrir-2009-206 · Cited by 11
Rudolph, J. W., Morrison, J. B., & Carroll, J. S. (2007) · Academy of Management Proceedings · doi:10.5465/ambpp.2007.26508215 · Cited by 11
“…debate, we do understand a great deal more about medication errors, hand-off related errors, hospital-acquired infections, and wrong-side procedures than we did 10 years ago (Campion, 2003; Gandhi, 2005; Heimann, 2005; Jagsi et al., 2005; Pronovost et al., 2003; Weick, Sutcliffe, & Obstfeld, 2005).”
BackgroundLesselroth, B., Dorr, D. A., Adams, K. A., Church, V., Adams, S., Mazur, D. J., Russ, Y., Felder, R. S., & Douglas, D. (2011) · Human Factors and Ergonomics in Manufacturing & Service Industries · doi:10.1002/hfm.20287 · Cited by 10
“…Factors and Ergonomics in Manufacturing & Service Industries 22 (1) 72–86 (2012) c© 2011 Wiley Periodicals, Inc. and poor interprovider communication (Pronovost et al., 2003; Boockvar, Carlson LaCorte, Giambanco, Fridman, & Siu, 2006; Varkey & Resar, 2006; Vira et al., 2006; Orrico, 2008; Pippins…”
Metadata
- Authors
- Pronovost, P., Weast, B., Schwarz, M., Wyskiel, R. M., Prow, D., Milanovich, S. N., Berenholtz, S., Dorman, T., & Lipsett, P.
- Affiliations
- Johns Hopkins University (US)
- Corresponding author
- Pronovost, Peter
- Venue
- Journal of Critical Care
- Publisher
- Elsevier BV
- Published
- 2003-12
- Volume
- 18
- Issue
- 4
- Pages
- 201-205
- ISSN
- 0883-9441 (ISSN-L)
- OpenAlex
- W2137815358
- Cited by
- 371
- References
- 20
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 11 · 2023: 11 · 2022: 12 · 2021: 12 · 2020: 12 · 2019: 13 · 2018: 18 · 2017: 23 · 2016: 15 · 2015: 27 · 2014: 17 · 2013: 20 · 2012: 20
- FWCI
- 17.34
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Critical Care (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Patient Safety and Medication Errors
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Pharmacovigilance and Adverse Drug Reactions
- Keywords
- medication reconciliation, medication errors, adverse drug reactions, intensive care unit discharge, surgical intensive care unit, electronic health records, medication orders, patient safety
- MeSH terms
- Continuity of Patient Care, Hospitals, University, Humans, Intensive Care Units, Medication Errors, Medication Systems, Hospital, Patient Care Team, Patient Transfer, Quality Assurance, Health Care
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