The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Varicella-zoster virus reactivation after SARS-CoV-2 BNT162b2 mRNA vaccination: Report of 5 cases
Open accessAbstract
A few months ago, we reported that to consider vesicular exanthems associated with COVID-19, varicella-zoster virus (VZV) and herpes simplex virus must be ruled out.1 The natural history of herpes zoster is influenced by the immune status of the host. Reactivation is influenced by age-related immunosenescence, disease-related immunocompromised state, or iatrogenic immunosuppression, with age being the major risk factor for most cases of herpes zoster. Among VZV reactivation triggers, vaccines are not common, and excluding herpes zoster appearing after VZV vaccination, we have found only 1 case of a child who experienced herpes zoster after diphtheria/tetanus/acellular pertussis, inactivated polio, Haemophilus influenzae type b, and meningococcal C vaccine.
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“Case reports on HZ following the BNT162b2 mRNA vaccination in subjects without immunosuppressive treatment 45 46 and in one patient with AAV in remission 47 were recently published.”
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Cites
Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
Polack, F. P., Thomas, S. J., Kitchin, N., Absalon, J., Gurtman, A., Lockhart, S., Perez, J. L., Pérez Marc, G., Moreira, E. D., Zerbini, C., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2034577 · Cited by 14,592 · cited 1×
“However, the adverse event reporting method did not specify the type of adverse event but just the severity.(4) Patients receiving the BNT162b2 mRNA COVID19 vaccine apparently do not suffer from lymphopenia and do not have symptoms suggesting cytokine release.”
Method
Research works printed but not linked: 6
- Llamas-Velasco, 2020, Reply to “Varicella-like exanthem as a specific COVID-19-associated skin manifestation: multicenter case series of 22 patients”: to consider varicella-like exanthem associated with COVID-19, virus varicella zoster and virus herpes simplex must be ruled out, J Am Acad Dermatol, 83, e253, 10.1016/j.jaad.2020.04.180 · DOI
- Patel, 2005, Varicella-zoster reactivation in a patient receiving routine revaccinations after an allogeneic hemopoietic progenitors transplant, J Pediatr Hematol Oncol, 27, 106, 10.1097/01.mph.0000153442.42030.74 · DOI
- Bostan, 2021, Herpes zoster following inactivated COVID-19 vaccine: a coexistence or coincidence?, J Cosmet Dermatol, 10.1111/jocd.14035 · DOI · Paper page
- Fernandez-Nieto, 2020, Comment on: “to consider varicella-like exanthem associated with COVID-19, virus varicella zoster and virus herpes simplex must be ruled out. Characterization of herpetic lesions in hospitalized COVID-19 patients”, J Am Acad Dermatol, 83, e257, 10.1016/j.jaad.2020.06.063 · DOI
- Galván Casas, 2020, Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases, Br J Dermatol, 183, 71, 10.1111/bjd.19163 · DOI
- Pérez-Farinós, 2007, Varicella and herpes zoster in Madrid, based on the Sentinel General Practitioner Network: 1997-2004, BMC Infect Dis, 7, 59, 10.1186/1471-2334-7-59 · DOI
Metadata
- Authors
- Rodríguez-Jiménez, P., Chicharro, P., Cabrera, L.-M., Seguí, M., Morales-Caballero, Á., Llamas-Velasco, M., & Sánchez-Pérez, J.
- Affiliations
- Hospital Universitario de La Princesa (ES)
- Venue
- JAAD Case Reports
- Publisher
- Elsevier BV
- Published
- 2021-06
- Volume
- 12
- Pages
- 58-59
- ISSN
- 2352-5126 (ISSN-L)
- PMC
- PMC8071473
- OpenAlex
- W3158168727
- Cited by
- 122
- References
- 1
- Citations by year
- 2025: 3 · 2024: 8 · 2023: 34 · 2022: 45 · 2021: 32
- FWCI
- 21.44
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- JAAD Case Reports (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Herpesvirus Infections and Treatments
- Health Sciences › Medicine › Dermatology › Dermatological and COVID-19 studies
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Keywords
- varicella-zoster virus reactivation, herpes zoster, BNT162b2 mRNA vaccine, COVID-19 vaccination, vaccine adverse events, immunosenescence, immunocompromised state, iatrogenic immunosuppression, age as risk factor
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- CoChat. (2026). Citation check: Varicella-zoster virus reactivation after SARS-CoV-2 BNT162b2 mRNA vaccination: Report of 5 cases. https://app.cochat.ai/papers/10.1016/j.jdcr.2021.04.014
- The paper
- Rodríguez-Jiménez, P., Chicharro, P., Cabrera, L.-M., Seguí, M., Morales-Caballero, Á., Llamas-Velasco, M., & Sánchez-Pérez, J. (2021). Varicella-zoster virus reactivation after SARS-CoV-2 BNT162b2 mRNA vaccination: Report of 5 cases. JAAD Case Reports. https://doi.org/10.1016/j.jdcr.2021.04.014
