Complete rehabilitation of compromised full dentitions with adhesively bonded all-ceramic single-tooth restorations: Long-term outcome in patients with and without amelogenesis imperfecta
Abstract
Objectives This clinical follow-up evaluated the long-term outcome of full-mouth rehabilitations with adhesively bonded all-ceramic restorations in patients suffering from amelogenesis imperfecta (AI) or affected by extensive tooth wear including a loss of the vertical dimension of occlusion. Materials and methods Included for evaluation were all patients treated with adhesively bonded monolithic single-tooth restorations made of silicate or lithium disilicate ceramics; allowing a maximum four missing teeth and a facial feldspathic veneering of LDS anterior crowns. After treatment, patients have been enrolled in a recall program for dental check-ups including quality assessment of the restorations. Patients answered the oral health impact profile (OHIP-14) at their last visit. Results Seventeen patients (mean age = 35 ± 18 years) were observed up to 16.5 years (mean: 6.2 ± 3.8 years). 12 out of 450 restorations failed due to core fracture (n = 7), tooth fracture (n = 2), one secondary caries, one chip-off grade 3, and one fixed dental prosthesis due to discomfort. The overall mean survival rate of the single-tooth restorations was estimated 99.4% at 5 and 91.4% at 10 years. The overall mean success rate was estimated 92.6% at 5 and 81.4% at 10 years, mainly due to chip-offs and crack formation (27 out of 31 relative failures). The mean annual failure rates (AFR) range between 1.5 and 2% over the years, but non-AI patients were affected more frequently by early technical compl…
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Only 1 study compared treatment success in individuals with AI with that of an independent control group.
“Only 1 study compared treatment success in individuals with AI with that of an independent control group (Klink et al. 2018).”
From Dental Management of Genetic Dental Disorders: A Critical Review (2025) · cites this paper as Klink et al. 2018
Studies in patients with AI have shown that the early use of indirect restorations in the second decade of life is associated with positive effects.
“Interestingly, studies in patients with AI have shown that the early use of indirect restorations in the second decade of life is associated with positive effects (e.g., Pousette Lundgren et al. 2015; Klink et al. 2018; Lundgren et al. 2018) (Table 1).”
From Dental Management of Genetic Dental Disorders: A Critical Review (2025) · cites this paper as Klink et al. 2018
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Ohrvik, H. G., & Hjortsjö, C. (2020) · Clinical and Experimental Dental Research · doi:10.1002/cre2.243 · Cited by 34 · see citing works
Dental Management of Genetic Dental Disorders: A Critical Review
Dujic, H., Bücher, K., Schüler, I. M., Schmidt, P., Hertel, S., Timpel, J., Jablonski-Momeni, A., Schilke, R., Kapferer-Seebacher, I., Zschocke, J., et al. (2025) · Journal of Dental Research · doi:10.1177/00220345241305330 · Cited by 8 · see citing works
“Interestingly, studies in patients with AI have shown that the early use of indirect restorations in the second decade of life is associated with positive effects (e.g., Pousette Lundgren et al. 2015; Klink et al. 2018; Lundgren et al. 2018) (Table 1).”
- Authors
- Klink, A., Groten, M., & Huettig, F.
- Affiliations
- Universitätsklinikum Tübingen (DE)
- Corresponding author
- Huettig, Fabian
- Venue
- Journal of Dentistry
- Publisher
- Elsevier BV
- Published
- 2018-03
- Volume
- 70
- Pages
- 51-58
- ISSN
- 0300-5712 (ISSN-L)
- OpenAlex
- W2778058638
- Cited by
- 27
- References
- 0
- Citations by year
- 2026: 2 · 2025: 7 · 2024: 6 · 2023: 2 · 2022: 1 · 2021: 1 · 2020: 2 · 2019: 3 · 2018: 3
- FWCI
- 3.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Dentistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Dentistry › Orthodontics › Dental materials and restorations
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › dental development and anomalies
- Health Sciences › Health Professions › Emergency Medical Services › Dental Trauma and Treatments
- Keywords
- amelogenesis imperfecta, lithium disilicate, silicate ceramics, full mouth rehabilitation, tooth wear, vertical dimension of occlusion, restoration failure, annual failure rate, marginal adaptation, bruxism, OHIP-14, long-term clinical outcomes
- MeSH terms
- Adult, Amelogenesis Imperfecta, Dental Bonding, Bruxism, Ceramics, Dental Cements, Dental Materials, Dental Porcelain, Dental Veneers, Dentition, Female, Humans, Incisor, Male, Middle Aged, Oral Health, Periodontal Index, Time Factors, Tooth Fractures, Survival Rate, Treatment Outcome, Dental Marginal Adaptation, Dental Restoration Failure, Young Adult, Tooth Wear
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