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Cited by 37Dental materials and restorationsdental development and anomaliesDental Trauma and Treatments

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Crown therapy in young individuals with amelogenesis imperfecta: Long term follow-up of a randomized controlled trial

Lundgren, Gunilla Pousette, Vestlund, Gun-Inger Morling, Dahllöf, Göran·2018·Journal of Dentistry
DOI 10.1016/j.jdent.2018.06.020
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Abstract

Objectives Amelogenesis imperfecta (AI) is a rare, genetically determined defect in enamel mineralization. Several problems are associated with AI: hypersensitivity, wear, restorations requiring replacement, gingivitis, aesthetic problems, and social avoidance. We conducted a randomized controlled trial of crown therapy in young individuals with AI showing excellent results. This study reports results from a long-term-follow-up with focus on quality, longevity and adverse events. Methods The RCT included 27 patients (aged 11-22 years) with severe AI in need of crown therapy and used a split-mouth technique. After placing 119 Procera ® crowns and 108 IPS e.max Press crowns following randomization, we assessed longevity, quality, adverse events, and tooth sensitivity and calculated survival rates and success rates. Results We followed the original 227 crowns for 4.3-7.4 years (mean 5.5 ± 0.8). In all, 79% (193) crowns were followed for at least 5 years. The survival rate was 99.6% and the success rate, 94.7%; 95% of the crowns had excellent or acceptable quality. Due to suboptimal marginal integrity, 4% of the crowns required adjustment. Sensitivity problems decreased after crown therapy (p Conclusions Ceramic crown therapy in adolescents and young adults with severe forms of AI show excellent survival and success rates and longevity with few adverse events. Clinical significance Ceramic crown therapy can be recommended for adolescents and young adults with severe forms of amel…

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  • Studies in patients with AI have shown that the early use of indirect restorations in the second decade of life is associated with positive effects.

    “Interestingly, studies in patients with AI have shown that the early use of indirect restorations in the second decade of life is associated with positive effects (e.g., Pousette Lundgren et al. 2015; Klink et al. 2018; Lundgren et al. 2018) (Table 1).”

    From Dental Management of Genetic Dental Disorders: A Critical Review (2025) · cites this paper as Lundgren et al. 2018

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References 37 · Cited by 37

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  1. Collins, 1999, Dental anomalies associated with amelogenesis imperfecta: a radiographic assessment, Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod., 88, 358, 10.1016/S1079-2104(99)70043-0 · DOI
  2. Poulsen, 2008, Amelogenesis imperfecta - a systematic literature review of associated dental and oro-facial abnormalities and their impact on patients, Acta Odontol. Scand., 66, 193, 10.1080/00016350802192071 · DOI
  3. Coffield, 2005, The psychosocial impact of developmental dental defects in people with hereditary amelogenesis imperfecta, J. Am. Dent. Assoc., 136, 620, 10.14219/jada.archive.2005.0233 · DOI
  4. Pousette Lundgren, 2014, Outcome of restorative treatment in young patients with amelogenesis imperfecta. a cross-sectional, retrospective study, J. Dent., 42, 1382, 10.1016/j.jdent.2014.07.017 · DOI
  5. McDonald, 2012, Managing the paediatric patient with amelogenesis imperfecta, Br. Dent. J., 212, 425, 10.1038/sj.bdj.2012.366 · DOI
  6. Aldred, 2003, It’s only teeth - are there limits to genetic testing?, Clin. Genet., 63, 333, 10.1034/j.1399-0004.2003.00045.x · DOI
  7. Pousette Lundgren, 2015, Oral health-related quality of life before and after crown therapy in young patients with amelogenesis imperfecta, Health Qual. Life Outcomes, 13, 197, 10.1186/s12955-015-0393-3 · DOI · Paper page
  8. Pousette Lundgren, 2016, Amelogenesis Imperfecta and Early Restorative Crown Therapy: An Interview Study with Adolescents and Young Adults on Their Experiences, PLoS One, 11, 10.1371/journal.pone.0156879 · DOI
  9. Parekh, 2014, How do children with amelogenesis imperfecta feel about their teeth?, Int. J. Paediatr. Dent., 24, 326, 10.1111/ipd.12080 · DOI · Paper page
  10. Crawford, 2007, Amelogenesis imperfecta, Orphanet J. Rare Dis., 17, 10.1186/1750-1172-2-17 · DOI
  11. Malik, 2012, The interdisciplinary management of patients with amelogenesis imperfecta - restorative dentistry, Br. Dent. J., 212, 537, 10.1038/sj.bdj.2012.469 · DOI
  12. Markovic, 2010, Case series: clinical findings and oral rehabilitation of patients with amelogenesis imperfecta, Eur. Arch. Paediatr. Dent., 11, 201, 10.1007/BF03262745 · DOI
  13. Chen, 2013, Assessment of restorative treatment of patients with amelogenesis imperfecta, Pediatr. Dent., 35, 337
  14. Pousette Lundgren, 2015, A Randomized Controlled Trial of Crown Therapy in Young Individuals with Amelogenesis Imperfecta, J. Dent. Res., 94, 1041, 10.1177/0022034515584385 · DOI
  15. Anusavice, 2012, Standardizing failure, success, and survival decisions in clinical studies of ceramic and metal-ceramic fixed dental prostheses, Dent. Mater., 28, 102, 10.1016/j.dental.2011.09.012 · DOI
  16. Sundell, 1985, Hereditary amelogenesis imperfecta. I. Epidemiology and clinical classification in a Swedish child population, Swed. Dent. J., 9, 157
  17. Gadhia, 2012, Amelogenesis imperfecta: an introduction, Br. Dent. J., 212, 377, 10.1038/sj.bdj.2012.314 · DOI
  18. Amarante, 1998, Impact of diagnostic criteria on the prevalence of dental caries in Norwegian children aged 5, 12 and 18 years, Community Dent. Oral Epidemiol., 26, 87, 10.1111/j.1600-0528.1998.tb01933.x · DOI
  19. Ainamo, 1975, Problems and proposals for recording gingivitis and plaque, Int. Dent. J., 25, 229
  20. Ryge, 1983, Assessment of the clinical quality of health care. Search for a reliable method, Eval. Health Prof., 6, 311, 10.1177/016327878300600305 · DOI
  21. Ryge, 1973, Evaluating the clinical quality of restorations, J. Am. Dent. Assoc., 87, 369, 10.14219/jada.archive.1973.0421 · DOI
  22. Orstavik, 1986, The periapical index: a scoring system for radiographic assessment of apical periodontitis, Endod. Dent. Traumatol., 2, 20, 10.1111/j.1600-9657.1986.tb00119.x · DOI
  23. Price, 1983, The validation of visual analogue scales as ratio scale measures for chronic and experimental pain, Pain, 17, 45, 10.1016/0304-3959(83)90126-4 · DOI · Paper page
  24. Berge, 1988, Visual analogue scale assessment of postoperative swelling. A study of clinical inflammatory variables subsequent to third-molar surgery, Acta Odontol. Scand., 46, 233, 10.3109/00016358809004772 · DOI
  25. Lovgren, 2016, Validity of three screening questions (3Q/TMD) in relation to the DC/TMD, J. Oral Rehabil., 43, 729, 10.1111/joor.12428 · DOI
  26. Faria-e-Silva, 2011, Hardness and microshear bond strength to enamel and dentin of permanent teeth with hypocalcified amelogenesis imperfecta, Int. J. Paediatr. Dent., 21, 314, 10.1111/j.1365-263X.2011.01129.x · DOI
  27. Saroglu, 2006, Effect of deproteinization on composite bond strength in hypocalcified amelogenesis imperfecta, Oral Dis., 12, 305, 10.1111/j.1601-0825.2005.01199.x · DOI
  28. Etman, 2010, Three-year clinical evaluation of two ceramic crown systems: a preliminary study, J. Prosthet. Dent., 103, 80, 10.1016/S0022-3913(10)60010-8 · DOI
  29. Fabbri, 2014, Clinical evaluation of 860 anterior and posterior lithium disilicate restorations: retrospective study with a mean follow-up of 3 years and a maximum observational period of 6 years, Int. J. Periodontics Restorative Dent., 34, 165, 10.11607/prd.1769 · DOI
  30. Pieger, 2014, Clinical outcomes of lithium disilicate single crowns and partial fixed dental prostheses: a systematic review, J. Prosthet. Dent., 112, 22, 10.1016/j.prosdent.2014.01.005 · DOI
  31. Pjetursson, 2015, All-ceramic or metal-ceramic tooth-supported fixed dental prostheses (FDPs)? A systematic review of the survival and complication rates. Part II: multiple-unit FDPs, Dent. Mater., 31, 624, 10.1016/j.dental.2015.02.013 · DOI
  32. Krieger, 2009, Failures and complications in patients with birth defects restored with fixed dental prostheses and single crowns on teeth and/or implants, Clin. Oral Implants Res., 20, 809, 10.1111/j.1600-0501.2009.01720.x · DOI
  33. Pjetursson, 2008, A systematic review of the survival and complication rates of resin-bonded bridges after an observation period of at least 5 years, Clin. Oral Implants Res., 19, 131, 10.1111/j.1600-0501.2007.01527.x · DOI
  34. Yaman, 2014, Microtensile bond strength to enamel affected by hypoplastic amelogenesis imperfecta, J. Adhes. Dent., 16, 7
  35. Busscher, 2010, Biofilm formation on dental restorative and implant materials, J. Dent. Res., 89, 657, 10.1177/0022034510368644 · DOI
  36. Lauridsen, 2012, Pattern of traumatic dental injuries in the permanent dentition among children, adolescents, and adults, Dent. Traumatol., 28, 358, 10.1111/j.1600-9657.2012.01133.x · DOI

Metadata

Authors
Lundgren, G. P., Vestlund, G.-I. M., & Dahllöf, G.
Affiliations
Karolinska Institutet (SE)
Corresponding author
Lundgren, Gunilla Pousette
ORCID
Venue
Journal of Dentistry
Publisher
Elsevier BV
Published
2018-09
Volume
76
Pages
102-108
ISSN
0300-5712 (ISSN-L)
DOI
10.1016/j.jdent.2018.06.020
OpenAlex
W2881832507
Cited by
37
References
37
Citations by year
2026: 3 · 2025: 5 · 2024: 6 · 2023: 9 · 2022: 6 · 2021: 3 · 2019: 5
FWCI
2.67
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Journal of Dentistry (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Dentistry › General Dentistry › Dental materials and restorations
  • Health Sciences › Dentistry › General Dentistry › dental development and anomalies
  • Health Sciences › Dentistry › General Dentistry › Dental Trauma and Treatments
Keywords
amelogenesis imperfecta, ceramic crowns, IPS e.max Press, crown survival, dentin hypersensitivity, marginal adaptation, apical periodontitis, dental trauma, adolescents and young adults, enamel defects, long-term follow-up
MeSH terms
Adolescent, Adult, Amelogenesis Imperfecta, Ceramics, Child, Crowns, Dental Porcelain, Dentin Sensitivity, Female, Follow-Up Studies, Humans, Male, Periapical Periodontitis, Young Adult

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