Cited by 25Dental materials and restorationsEndodontics and Root Canal TreatmentsBone and Dental Protein Studies

Dentine disorders and adhesive treatments: A systematic review

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Massé, Léa, Etienne, Olivier, Noirrit-Esclassan, Emmanuelle, Bailleul-Forestier, Isabelle, Garot, Elsa·2021·Journal of Dentistry

Abstract

Objectives A better understanding of the microstructure and mechanical properties of enamel and dentine may enable practitioners to apply the current adhesive dentistry protocols to clinical cases involving dentine disorders (dentinogenesis imperfecta or dentine dysplasia). Data/sources Publications (up to June 2020) investigating the microstructure of dentine disorders were browsed in a systematic search using the PubMed/Medline, Embase and Cochrane Library electronic databases. Two authors independently selected the studies, extracted the data in accordance with the PRISMA statement, and assessed the risk of bias with the Critical Appraisal Checklist. A Mann-Whitney U test was computed to compare tissues damage related to the two dentine disorders of interest. Study selection From an initial total of 642 studies, only 37 (n = 164 teeth) were included in the present analysis, among which 18 investigating enamel (n = 70 teeth), 15 the dentine-enamel junction (n = 62 teeth), and 35 dentine (n = 156 teeth). Dentine is damaged in cases of dentinogenesis imperfecta and osteogenesis imperfecta (p = 2.55E-21 and p = 3.99E-21, respectively). These studies highlight a reduction in mineral density, hardness, modulus of elasticity and abnormal microstructure in dentine disorders. The majority of studies report an altered dentine-enamel junction in dentinogenesis imperfecta and in osteogenesis imperfecta (p = 6.26E-09 and p = 0.001, respectively). Interestingly, enamel is also affected in cases of dentinogenesis imperfecta (p = 0.0013), unlike to osteogenesis imperfecta (p = 0.056). Conclusions Taking into account all these observations, only a few clinical principles may be favoured in the case of adhesive cementation: (i) to preserve the residual enamel to enhance bonding, (ii) to sandblast the tooth surfaces to increase roughness, (iii) to choose a universal adhesive and reinforce enamel and dentine by means of infiltrant resins. As these recommendations are mostly based on in vitro studies, future in vivo studies should be conducted to confirm these hypotheses.

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Crossref · 10.1016/j.jdent.2021.103654

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  • The review revealed very few in vitro studies.

    “very few in vitro studies (e.g., Yaman et al. 2014; Epasinghe and Yiu 2018; Massé et al. 2021)”

    From Dental Management of Genetic Dental Disorders: A Critical Review (2025) · cites this paper as Massé et al. 2021

    The Study selection section reports 37 included studies, and the Discussion explicitly refers to in vitro studies reviewed by the paper. It does not say that there were ‘very few’ in vitro studies; moreover, Massé et al. is a review of such studies, not itself an in vitro study. (LLM, conf=0.78)

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Authors
Massé, L., Etienne, O., Noirrit-Esclassan, E., Bailleul-Forestier, I., & Garot, E.
Affiliations
  • Université de Bordeaux (FR)
  • Inserm (FR)
Corresponding author
Garot, Elsa
Venue
Journal of Dentistry
Publisher
Elsevier BV
Published
2021-06
Volume
109
Pages
103654
ISSN
0300-5712 (ISSN-L)
OpenAlex
W3147377016
Cited by
25
References
67
Citations by year
2026: 4 · 2025: 3 · 2024: 11 · 2023: 2 · 2022: 4 · 2021: 1
FWCI
1.13
Type
journal article
Language
en
Open access
Locations
  • Journal of Dentistry (acceptedVersion)
  • PubMed (publishedVersion)
  • HAL (submittedVersion, cc-by-nc)
Topics
  • Health Sciences › Dentistry › Orthodontics › Dental materials and restorations
  • Health Sciences › Dentistry › Oral Surgery › Endodontics and Root Canal Treatments
  • Health Sciences › Medicine › Rheumatology › Bone and Dental Protein Studies
Keywords
dentinogenesis imperfecta, osteogenesis imperfecta, adhesive dentistry, enamel microstructure, enamel-dentine junction, elastic modulus, universal adhesive, sandblasting, tooth surface roughness
MeSH terms
Dental Cements, Dental Enamel, Dentin, Hardness, Tooth

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