The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Acquired salivary pellicle and oral diseases: A literature review
Open accessAbstract
As soon as saliva contacts the teeth surface, salivary proteins adhere to the tooth surface to form acquired salivary pellicle. The formation of this acquired salivary pellicle is a dynamic and selective process of macromolecular adsorption and desorption. Although acquired salivary pellicle contains proteins and peptides, it also contains lipids, and other macro-molecules, all of which contribute to its protective properties. Acquired salivary pellicle is related to the development of common oral diseases, such as erosion, dental caries, and periodontal disease. Acquired salivary pellicle acts as a natural barrier to prevent a tooth's surface from making direct contact with acids and to protect it from erosive demineralization. It contributes to the control of dental erosion by modulating calcium and phosphate concentrations on the tooth surface. It also influences the initial colonizer of oral biofilm and affects the transportation pathway of the acidic products of cariogenic bacteria, which affects the development of dental caries. In addition, it influences periodontal disease by acting on the colonization of periodontal pathogens. This paper's aim is to provide an overview of the acquired salivary pellicle, highlighting its composition, structure, function, role in common oral diseases, and modification for the prevention of oral diseases.
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“The enamel surfaces are coated by an acquired salivary pellicle, composed of proteins, lipids, glycoproteins, and glycolipids that permit initial adherence by primary colonizers.229, 230”
From The oral microbiome: Role of key organisms and complex networks in oral health and disease (2021) · cites this paper as [229]
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Metadata
- Authors
- Chawhuaveang, D. D., Yu, O. Y., Yin, I. X., Lam, W. Y.-H., Mei, M. L., & Chu, C.-H.
- Affiliations
- University of Hong Kong (HK)
- University of Otago (NZ)
- Corresponding author
- Chu, Chun-Hung
- Venue
- Journal of Dental Sciences
- Publisher
- Elsevier BV
- Published
- 2021-01
- Volume
- 16
- Issue
- 1
- Pages
- 523-529
- ISSN
- 1991-7902 (ISSN-L)
- PMC
- PMC7770358
- OpenAlex
- W3094233644
- Cited by
- 134
- References
- 39
- Citations by year
- 2026: 21 · 2025: 27 · 2024: 35 · 2023: 22 · 2022: 20 · 2021: 9
- FWCI
- 3.09
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Journal of Dental Sciences (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- General Research Fund of Research Grants Council of Hong Kong SAR, China (17100820)
- Topics
- Health Sciences › Dentistry › General Dentistry › Dental Erosion and Treatment
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Health Sciences › Dentistry › General Dentistry › Dental Health and Care Utilization
- Keywords
- salivary proteins, dental erosion, dental caries, periodontal disease, dental plaque, demineralization, calcium and phosphate, cariogenic bacteria, periodontal pathogens, oral disease prevention
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