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Occurrence and removal of antibiotics in ecological and conventional wastewater treatment processes: A field study
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The occurrence and removal of 19 antibiotics (including four macrolides, eight sulfonamides, three fluoroquinolones, three tetracyclines, and trimethoprim) were investigated in two ecological (constructed wetland (CW) and stabilization pond (SP)) and two conventional wastewater treatment processes (activated sludge (AS) and micro-power biofilm (MP)) in a county of eastern China. All target antibiotics were detected in the influent and effluent samples with detection frequencies of >90%. Clarithromycin, ofloxacin, roxithromycin and erythromycin-H2O were the dominant antibiotics with maximum concentrations reaching up to 6524, 5411, 964 and 957 ng/L, respectively; while the concentrations of tiamulin, sulfamerazine, sulfathiazole, sulfamethazine, sulfamethizole and sulfisoxazole were below 10 ng/L. Although the mean effluent concentrations of target antibiotics were obviously lower than the influent ones (except ciprofloxacin), their removals were usually incomplete. Principal component analysis showed that the AS and CW outperformed the MP and SP processes and the AS performed better than the CW process in terms of antibiotics removal. Both the AS and CW processes exhibited higher removal efficiencies in summer than in winter, indicating biological degradation could play an important role in antibiotics removal. Because of the incomplete removal, the total concentration of detected antibiotics increased in the mixing and downstream sections of a local river receiving the efflu…
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“extensive abuse of antibiotic usage by humans has contributed to an increase in the concentration of various antibiotics in our natural environment, including lakes, rivers, agriculture soil, waste and surface water (Dong et al., 2016;Ferro et al., 2016;Qian et al., 2016).”
From The Microbiota-Gut-Brain Axis (2019) · cites this paper as Dong et al., 2016
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Kolpin, D. W., Furlong, E. T., Meyer, M. T., Thurman, E. M., Zaugg, S. D., Barber, L. B., & Buxton, H. T. (2002) · Environmental Science & Technology · doi:10.1021/es011055j · Cited by 7,953
Occurrence of Antibiotics in the Aquatic Environment
Hirsch, R., Ternes, T., Haberer, K., & Kratz, K.-L. (1999) · Science of The Total Environment · doi:10.1016/s0048-9697(98)00337-4 · Cited by 2,140 · cited 3×
“Hirsch et al. (1999) reported that the effluent concentrations of ERY-H2O and ROX in theWWTPs of Germany could reach as high as 6 mg/L.”
BackgroundMethodInfluentialRemoval of Pharmaceuticals in Sewage Treatment Plants in Italy
Castiglioni, S., Bagnati, R., Fanelli, R., Pomati, F., Calamari, D., & Zuccato, E. (2006) · Environmental Science & Technology · doi:10.1021/es050991m · Cited by 841
Research works printed but not linked: 46
- Andreozzi, 2003, Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment, Chemosphere, 50, 1319, 10.1016/S0045-6535(02)00769-5 · DOI
- Batt, 2006, Evaluating the vulnerability of surface waters to antibiotic contamination from varying wastewater treatment plant discharges, Environ. Pollut., 142, 295, 10.1016/j.envpol.2005.10.010 · DOI
- Ben, 2008, Simultaneous determination of sulfonamides, tetracyclines and tiamulin in swine wastewater by solid-phase extraction and liquid chromatography-mass spectrometry, J. Chromatogr. A, 1202, 173, 10.1016/j.chroma.2008.07.014 · DOI
- Brown, 2006, Occurrence of antibiotics in hospital, residential, and dairy effluent, municipal wastewater, and the Rio Grande in New Mexico, Sci. Total Environ., 366, 772, 10.1016/j.scitotenv.2005.10.007 · DOI
- Choi, 2008, Seasonal variations of several pharmaceutical residues in surface water and sewage treatment plants of Han River, Korea, Sci. Total Environ., 405, 120, 10.1016/j.scitotenv.2008.06.038 · DOI
- Cizmas, 2015, Pharmaceuticals and personal care products in waters: occurrence, toxicity, and risk, Environ. Chem. Lett., 13, 381, 10.1007/s10311-015-0524-4 · DOI
- Clara, 2005, Removal of selected pharmaceuticals, fragrances and endocrine disrupting compounds in a membrane bioreactor and conventional wastewater treatment plants, Water Res., 39, 4797, 10.1016/j.watres.2005.09.015 · DOI
- Daughton, 1999, Pharmaceuticals and personal care products in the environment: agents of subtle change?, Environ. Health Perspect., 107, 907, 10.1289/ehp.99107s6907 · DOI
- Dolar, 2012, Removal of emerging contaminants from municipal wastewater with an integrated membrane system, MBR-RO, J. Hazard. Mater., 239, 64, 10.1016/j.jhazmat.2012.03.029 · DOI
- Dong, 1999, A description of outpatient drug use in rural China: evidence of differences due to insurance coverage, Int. J. Health Plan. Manag., 14, 41, 10.1002/(SICI)1099-1751(199901/03)14:1<41::AID-HPM529>3.0.CO;2-Q · DOI
- Dorival-García, 2013, Removal and degradation characteristics of quinolone antibiotics in laboratory-scale activated sludge reactors under aerobic, nitrifying and anoxic conditions, J. Environ. Manag., 120, 75
- Gao, 2012, Occurrence of antibiotics in eight sewage treatment plants in Beijing, China, Chemosphere, 86, 665, 10.1016/j.chemosphere.2011.11.019 · DOI
- Gao, 2012, Occurrence of pharmaceuticals in a municipal wastewater treatment plant: mass balance and removal processes, Chemosphere, 88, 17, 10.1016/j.chemosphere.2012.02.017 · DOI
- Gabet-Giraud, 2010, Occurrence and removal of estrogens and beta blockers by various processes in wastewater treatment plants, Sci. Total Environ., 408, 4257, 10.1016/j.scitotenv.2010.05.023 · DOI
- Gaulke, 2008, 17 alpha- ethinylestradiol transformation via abiotic nitration in the presence of ammonia oxidizing bacteria, Environ. Sci. Technol., 42, 7622, 10.1021/es801503u · DOI
- Giger, 2003, Occurrence and fate of antibiotics as trace contaminants in wastewaters, sewage sludges, and surface waters, Chimia, 57, 485, 10.2533/000942903777679064 · DOI
- Golet, 2003, Environmental exposure assessment of fluoroquinolone antibacterial agents from sewage to soil, Environ. Sci. Technol., 37, 3243, 10.1021/es0264448 · DOI
- Göbel, 2007, Fate of sulfonamides, macrolides, and trimethoprim in different wastewater treatment technologies, Sci. Total Environ., 372, 361, 10.1016/j.scitotenv.2006.07.039 · DOI
- Guerra, 2014, Occurrence and fate of antibiotic, analgesic/anti-inflammatory, and antifungal compounds in five wastewater treatment processes, Sci. Total Environ., 473–474, 235, 10.1016/j.scitotenv.2013.12.008 · DOI
- Gulkowska, 2008, Removal of antibiotics from wastewater by sewage treatment facilities in Hong Kong and Shenzhen, China, Water Res., 42, 395, 10.1016/j.watres.2007.07.031 · DOI
- Han Tran, 2009, The characteristics of enriched nitrifier culture in the degradation of selected pharmaceutically active compounds, J. Hazard. Mater., 171, 1051, 10.1016/j.jhazmat.2009.06.114 · DOI
- Hijosa-Valsero, 2010, Comprehensive assessment of the design configuration of constructed wetlands for the removal of pharmaceuticals and personal care products from urban wastewaters, Water Res., 44, 3669, 10.1016/j.watres.2010.04.022 · DOI
- Hu, 2003, Assessment of antibiotic prescription in hospitalized patients at a Chinese university hospital, J. Infect., 46, 161, 10.1053/jinf.2002.1078 · DOI · Paper page
- Hussain, 2011, Removal of ionophoric antibiotics in free water surface constructed wetlands, Ecol. Eng., 41, 13, 10.1016/j.ecoleng.2011.12.006 · DOI
- Joss, 2006, Biological degradation of pharmaceuticals in municipal wastewater treatment: proposing a classification scheme, Water Res., 40, 1686, 10.1016/j.watres.2006.02.014 · DOI
- Kim, 2005, Removal of antibiotics in wastewater: effect of hydraulic and solid retention times on the fate of tetracycline in the activated sludge process, Environ. Sci. Technol., 39, 5816, 10.1021/es050006u · DOI
- Kim, 2007, Occurrence and removal of pharmaceuticals and endocrine disruptors in South Korean surface, drinking, and waste waters, Water Res., 41, 1013, 10.1016/j.watres.2006.06.034 · DOI
- Koh, 2009, Influence of operating parameters on the biodegradation of steroid estrogens and nonylphenolic compounds during biological wastewater treatment processes, Environ. Sci. Technol., 43, 6646, 10.1021/es901612v · DOI
- Lin, 2010, High levels of perfluorochemicals in Taiwan's wastewater treatment plants and downstream rivers pose great risk to local aquatic ecosystems, Chemosphere, 80, 1167, 10.1016/j.chemosphere.2010.06.018 · DOI
- Lindberg, 2005, Screening of human antibiotic substances and determination of weekly mass flows in five sewage treatment plants in Sweden, Environ. Sci. Technol., 39, 3421, 10.1021/es048143z · DOI
- Le-Minh, 2010, Fate of antibiotics during municipal water recycling treatment processes, Water Res., 44, 4295, 10.1016/j.watres.2010.06.020 · DOI · Paper page
- Massey, 2010, Antibiotic fate and transport in three effluent-dominated Ozark streams, Ecol. Eng., 36, 930, 10.1016/j.ecoleng.2010.04.009 · DOI
- Peng, 2006, A preliminary study on the occurrence and behavior of sulfonamides, ofloxacin and chloramphenicol antimicrobials in wastewaters of two sewage treatment plants in Guangzhou, China, Sci. Total Environ., 371, 314, 10.1016/j.scitotenv.2006.07.001 · DOI
- Plosz, 2010, Diurnal variations in the occurrence and the fate of hormones and antibiotics in activated sludge wastewater treatment in Oslo, Norway, Sci. Total Environ., 408, 1915, 10.1016/j.scitotenv.2010.01.042 · DOI
- Pontes, 2009, Multiple antimicrobial resistance of gram-negative bacteria from natural oligotrophic lakes under distinct anthropogenic influence in a tropical region, Microb. Ecol., 58, 762, 10.1007/s00248-009-9539-3 · DOI
- Roberts, 2006, The occurrence of selected pharmaceuticals in wastewater effluent and surface waters of the lower Tyne catchment, Sci. Total Environ., 356, 143, 10.1016/j.scitotenv.2005.04.031 · DOI
- Roumie, 2005, Trends in antibiotic prescribing for adults in the United States–1995 to 2002, J. Gen. Intern. Med., 20, 697, 10.1111/j.1525-1497.2005.0148.x · DOI
- Sharma, 2016, A review of the influence of treatment strategies on antibiotic resistant bacteria and antibiotic resistance genes, Chemosphere, 150, 702, 10.1016/j.chemosphere.2015.12.084 · DOI
- Sponza, 2012, Removal of oxytetracycline (OTC) in a synthetic pharmaceutical wastewater by a sequential anaerobic multichamber bed reactor (AMCBR)/completely stirred tank reactor (CSTR) system: biodegradation and inhibition kinetics, Bioresour. Technol., 104, 100, 10.1016/j.biortech.2011.10.056 · DOI
- Suarez, 2010, Removal of pharmaceutical and personal care products (PPCPs) under nitrifying and denitrifying conditions, Water Res., 44, 3214, 10.1016/j.watres.2010.02.040 · DOI
- Ternes, 2007, Irrigation of treated wastewater in Braunschweig, Germany: an option to remove pharmaceuticals and musk fragrances, Chemosphere, 66, 894, 10.1016/j.chemosphere.2006.06.035 · DOI
- Vieno, 2006, Analysis of neutral and basic pharmaceuticals in sewage treatment plants and in recipient rivers using solid phase extraction and liquid chromatography-tandem mass spectrometry detection, J. Chromatogr. A, 1134, 101, 10.1016/j.chroma.2006.08.077 · DOI
- Wilkinson, 2016, Ecotoxic pharmaceuticals, personal care products, and other emerging contaminants: a review of environmental, receptor-mediated, developmental, and epigenetic toxicity with discussion of proposed toxicity to humans, Crit. Rev. Environ. Sci. Technol., 46, 336, 10.1080/10643389.2015.1096876 · DOI
- Xia, 2012, Effect of solids retention time on antibiotics removal performance and microbial communities in an A/O-MBR process, Bioresour. Technol., 106, 36, 10.1016/j.biortech.2011.11.112 · DOI
- Xu, 2007, Occurrence and elimination of antibiotics at four sewage treatment plants in the Pearl River Delta (PRD), South China, Water Res., 41, 4526, 10.1016/j.watres.2007.06.023 · DOI
- Yuan, 2014, Rapid detection of multiple class pharmaceuticals in both municipal wastewater and sludge with ultra high performance liquid chromatography tandem mass spectrometry, J. Environ. Sci. China, 26, 1949, 10.1016/j.jes.2014.06.022 · DOI
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Letsinger, S., Kay, P., Rodríguez-Mozaz, S., Villagrassa, M., Barceló, D., & Rotchell, J. M. (2019) · Science of The Total Environment · doi:10.1016/j.scitotenv.2019.04.182 · Cited by 104
Metadata
- Authors
- Dong, H., Yuan, X., Wang, W., & Qiang, Z.
- Affiliations
- Chinese Academy of Sciences (CN)
- Corresponding author
- Qiang, Zhimin
- Venue
- Journal of Environmental Management
- Publisher
- Elsevier BV
- Published
- 2016-08
- Volume
- 178
- Pages
- 11-19
- ISSN
- 0301-4797 (ISSN-L)
- OpenAlex
- W2344089381
- Cited by
- 185
- References
- 3
- Citations by year
- 2026: 7 · 2025: 10 · 2024: 23 · 2023: 15 · 2022: 31 · 2021: 29 · 2020: 18 · 2019: 20 · 2018: 16 · 2017: 11 · 2016: 5
- FWCI
- 9.45
- Type
- journal article
- Language
- en
- Open access
- green
- ir.rcees.ac.cn
- Licence
- cc-by-nc-sa
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- Locations
- Journal of Environmental Management (publishedVersion)
- PubMed (publishedVersion)
- Research Center for Eco-Environmental Sciences OpenIR (Chinese Academy of Sciences) (submittedVersion, cc-by-nc-sa)
- Funders
- European Union's Seventh Programme (318926)
- National Natural Science Foundation (51138009, 51408590)
- Ministry of Housing and Urban-Rural Development (2012ZX07313-001-07)
- Topics
- Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
- Physical Sciences › Environmental Science › Waste Management and Disposal › Constructed Wetlands for Wastewater Treatment
- Physical Sciences › Environmental Science › Waste Management and Disposal › Wastewater Treatment and Reuse
- Keywords
- antibiotics, antibiotic removal, wastewater treatment, constructed wetlands, stabilization ponds, activated sludge, macrolides, sulfonamides, fluoroquinolones, tetracycline, trimethoprim, seasonal variation, biodegradation, river pollution, rural wastewater
- MeSH terms
- Anti-Bacterial Agents, China, Humans, Seasons, Waste Disposal, Fluid, Water Pollutants, Chemical, Wetlands, Ponds, Wastewater
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