The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Screening of plants used in Danish folk medicine to treat memory dysfunction for acetylcholinesterase inhibitory activity
Abstract
Aqueous and methanolic extracts of 11 plants, used in Danish folk medicine for improvement of memory and cognition, and 3 Corydalis species were tested for acetylcholinesterase inhibitory activity using the Ellman colorimetric method. Significant inhibitory activity in dose-dependent manner was observed for extracts of Corydalis cava, Corydalis intermedia, Corydalis solida ssp. laxa and Corydalis solida ssp. slivenensis. Extracts of Ruta graveolens, Lavandula angustifolia, Rosmarinus officinalis, Petroselinum crispum and Mentha spicata exhibited moderate inhibition of the enzyme, defined as more than 15% at 0.1 mg/ml.
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“Both species contain rosmarinic acid that is active against amyloid fibrillation (Adsersen et al., 2006;Lobbens et al., 2017).”
From Multi-target neuroprotective effects of herbal medicines for Alzheimer's disease (2022) · cites this paper as Adsersen et al., 2006
In the citing paper
“Although R. officinalis and L. angustifolia extracts are low to moderate AChE inhibitors (Adsersen et al., 2006;Ferreira et al., 2006)”
From Multi-target neuroprotective effects of herbal medicines for Alzheimer's disease (2022) · cites this paper as Adsersen et al., 2006
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Clinical Pharmacy and Therapeutics
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Plant-insect coevolution and inhibition of acetylcholinesterase
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Acetylcholinesterase and butyrylcholinesterase inhibitory activity of some Turkish medicinal plants
Orhan, İ. E., Şener, B., Choudhary, M. I., & Khalid, A. (2004) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2003.11.016 · Cited by 302
Current drug targets for Alzheimer's disease treatment
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- Hwang, 1996, An acetylcholinesterase inhibitor isolated from Corydalis tuber and its mode of action, Korean Journal of Pharmacognosy, 27, 91
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Prado, K. E. (2022) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.9.2022.tde-25082022-094948
Jameel, M., Ali, A., Ahmad, W., Faiyazuddin, M., Haque, M. R., Meena, R., Sultan, S., & Ashraf, K. (2023) · Pharmacognosy Research · doi:10.5530/pres.15.4.064
Lavandula angustifolia and Cyperus rotundus Extract Treatments Ameliorate Copper Toxicity in Rats
Salari, M., Balooch, F. D., Fatemi, S. J., & Dogani, M. (2025) · Brain and Behavior · doi:10.1002/brb3.70624
Metadata
- Authors
- Adsersen, A., Gauguin, B., Gudiksen, L., & Jäger, A. K.
- Corresponding author
- Adsersen, Anne
- ORCID
- Jäger, Anna K.
- Venue
- Journal of Ethnopharmacology
- Publisher
- Elsevier BV
- Published
- 2006-04
- Volume
- 104
- Issue
- 3
- Pages
- 418-422
- ISSN
- 0378-8741 (ISSN-L)
- OpenAlex
- W1967774489
- Cited by
- 205
- References
- 28
- Citations by year
- 2025: 4 · 2024: 7 · 2023: 9 · 2022: 10 · 2021: 12 · 2020: 19 · 2019: 17 · 2018: 10 · 2017: 13 · 2016: 11 · 2015: 10 · 2014: 12 · 2013: 12 · 2012: 16
- FWCI
- 2.76
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Ethnopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- Funders
- Sundhed og Sygdom, Det Frie Forskningsråd
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Cholinesterase and Neurodegenerative Diseases
- Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plants and Neuroprotection
- Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plant Extracts Effects
- Keywords
- acetylcholinesterase inhibition, folk medicine, memory impairment, plant extracts, Corydalis, Corydalis cava, Corydalis solida, Ruta graveolens, Lavandula angustifolia, Rosmarinus officinalis, parsley, Mentha spicata, cognitive enhancement
- MeSH terms
- Acetylcholinesterase, Cholinesterase Inhibitors, Chromatography, Thin Layer, Denmark, Dose-Response Relationship, Drug, Medicine, Traditional, Memory Disorders, Plant Extracts, Plants, Medicinal, Nootropic Agents
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