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Cited by 369

The DOI matches its Crossref record; 79 of the 79 references it cites were found in a registry or an index.

Toxicity and mechanisms of action of titanium dioxide nanoparticles in living organisms

Hou, Jing, Wang, Luyao, Wang, Chunjie, Zhang, Songlin, Liu, Haiqiang, Li, Shiguo, Wang, Xiangke·2019·Journal of Environmental Sciences

Abstract

Titanium dioxide nanoparticles (TiO2 NPs) are one of the most widely used nanomaterials in the consumer products, agriculture, and energy sectors. Their large demand and widespread applications will inevitably cause damage to organisms and ecosystems. A better understanding of TiO2 NP toxicity in living organisms may promote risk assessment and safe use practices of these nanomaterials. This review summarizes the toxic effects of TiO2 NPs on multiple taxa of microorganisms, algae, plants, invertebrates, and vertebrates. The mechanism of TiO2 NP toxicity to organisms can be outlined in three aspects: The Reactive Oxygen Species (ROS) produced by TiO2 NPs following the induction of electron-hole pairs; cell wall damage and lipid peroxidation of the cell membrane caused by NP-cell attachment by electrostatic force owing to the large surface area of TiO2 NPs; and TiO2 NP attachment to intracellular organelles and biological macromolecules following damage to the cell membranes.

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Metadata

Authors
Hou, J., Wang, L., Wang, C., Zhang, S., Liu, H., Li, S., & Wang, X.
Venue
Journal of Environmental Sciences
Publisher
Elsevier BV
Published
2019-01
Volume
75
Pages
40-53
ISSN
1001-0742 (ISSN-L)
OpenAlex
W2810317794
Cited by
369
References
79
FWCI
12.20
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Toxicity and mechanisms of action of titanium dioxide nanoparticles in living organisms. https://app.cochat.ai/papers/10.1016/j.jes.2018.06.010
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Hou, J., Wang, L., Wang, C., Zhang, S., Liu, H., Li, S., & Wang, X. (2019). Toxicity and mechanisms of action of titanium dioxide nanoparticles in living organisms. Journal of Environmental Sciences. https://doi.org/10.1016/j.jes.2018.06.010

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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