The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Protective effects of galacturonic acid-rich vinegar brewed from Japanese pear in a dextran sodium sulfate-induced acute colitis model
Open accessAbstract
The effects of pear vinegar (PV), which was specially brewed for enhanced galacturonic acid content, on the DSS-induced ulcerative colitis (UC) mouse model were evaluated. PV improved clinical symptoms, colon inflammation, and histological tissue injury in the DSS-induced acute UC mouse model. Moreover, PV suppressed inflammation due to acute UC by suppressing the myeloperoxidase (MPO)-mediated activation of inflammatory cells such as leukocytes and decreasing the serum concentration of IL-6. Our results demonstrated the protective action of PV in the DSS-induced acute UC mouse model. On the other hand, commercial apple vinegar did not show a protective effect in the DSS-induced acute UC mouse model. Our findings indicate that PV may act as a new functional food for inflammatory bowel disease patients.
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In the citing paper
“Research experiments have proven that pear vinegar has an interesting ability in reducing serum IL-6 and IL-1ß concentrations [109].”
From Fruits Vinegar: Quality Characteristics, Phytochemistry, and Functionality (2021) · cites this paper as [109]
In the citing paper
“Previously, it proved that the pear vinegar ameliorates histological disorganization induced by dextran sodium sulfate (DSS) in an experimental animal model.”
From Fruits Vinegar: Quality Characteristics, Phytochemistry, and Functionality (2021) · cites this paper as [109]
Citations
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Metadata
- Authors
- Wakuda, T., Azuma, K., Saimoto, H., Ifuku, S., Morimoto, M., Arifuku, I., Asaka, M., Tsuka, T., Imagawa, T., Okamoto, Y., Osaki, T., & Minami, S.
- Affiliations
- Tottori University (JP)
- Tottori Institute of Industrial Technology (JP)
- Corresponding author
- Osaki, Tomohiro
- Venue
- Journal of Functional Foods
- Publisher
- Elsevier BV
- Published
- 2013-01
- Volume
- 5
- Issue
- 1
- Pages
- 516-523
- ISSN
- 1756-4646 (ISSN-L)
- OpenAlex
- W2095258336
- Cited by
- 23
- References
- 22
- Citations by year
- 2025: 1 · 2024: 5 · 2023: 2 · 2022: 1 · 2021: 3 · 2017: 1 · 2015: 2 · 2014: 5 · 2013: 3
- FWCI
- 1.93
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Functional Foods (publishedVersion, cc-by-nc-nd)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- galacturonic acid, ulcerative colitis, DSS-induced colitis, myeloperoxidase, interleukin-6, colonic inflammation, functional foods, inflammatory bowel disease, apple cider vinegar
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