Applications of new functions for inducing host defense peptides and synergy sterilization of medium chain fatty acids in substituting in-feed antibiotics.
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Incubation of lauric acid enhanced the innate immune defense of human sebocytes by upregulating gene and protein expression of β-defensin-2.
“Indeed, new evidence points out that incubation of lauric acid, also found in human sebum, enhanced the innate immune defense of human sebocytes by upregulating the gene and protein expression of β-defensin-2, one of the most represented antimicrobial peptides detected in the skin (Zhou et al., 2019).”
From Insect Derived Lauric Acid as Promising Alternative Strategy to Antibiotics in the Antimicrobial Resistance Scenario (2021) · cites this paper as Zhou et al., 2019
Medium-chain fatty acids show low solubility and unpleasant odors that stimulate the release of cholecystokinin and reduce the feed intake of animals.
“Moreover, MCFAs show low solubility and unpleasant odors that stimulate the release of cholecystokinin and reduce the feed intake of animals.”
From Insect Derived Lauric Acid as Promising Alternative Strategy to Antibiotics in the Antimicrobial Resistance Scenario (2021) · cites this paper as Zhou et al., 2019
Encapsulation of medium-chain fatty acids could be a suitable solution to overcome their low solubility and unpleasant odors.
“Encapsulation of MCFAs could be a suitable solution to overcome these limits (Zhou et al., 2019).”
From Insect Derived Lauric Acid as Promising Alternative Strategy to Antibiotics in the Antimicrobial Resistance Scenario (2021) · cites this paper as Zhou et al., 2019
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References 127 · Cited by 20
- Authors
- Zhou, Z., Huang, J., Hao, H., Wei, H., Zhou, Y., & Peng, J.
- Affiliations
- Huazhong Agricultural University (CN)
- Corresponding author
- Zhou, Zhongxin
- Peng, Jian
- Venue
- Journal of Functional Foods
- Publisher
- Elsevier BV
- Published
- 2019-01
- Volume
- 52
- Pages
- 348-359
- ISSN
- 1756-4646 (ISSN-L)
- OpenAlex
- W2901688830
- Cited by
- 20
- References
- 127
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 6 · 2020: 3 · 2019: 1
- FWCI
- 2.41
- Type
- journal article
- Language
- en
- Open access
- green
- doaj.org
- Licence
- Locations
- Journal of Functional Foods (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Key Research and Development Program of China (2017YFD0502200, 2016YFD0501210)
- Wuhan Municipal Science and Technology (2016020101010078)
- Fundamental Research Funds for the Central Universities (2662018PY017)
- National Natural Science Foundation of China (21204020)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Nutrition and Physiology
- Life Sciences › Immunology and Microbiology › Microbiology › Antimicrobial Peptides and Activities
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Keywords
- medium-chain fatty acids, antibiotic alternatives, antibiotic growth promoters, antimicrobial peptides, innate immunity, organic acids, encapsulation, feed additives, antimicrobial activity, chemical stability, antimicrobial resistance
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