CoChat
Sign Up
Cited by 31

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Roles of various enzymes in the biotransformation of 6:2 fluorotelomer alcohol (6:2 FTOH) by a white-rot fungus

Merino, Nancy, Wang, Ning, Gao, Yifan, Wang, Meng, Mahendra, Shaily·2023·Journal of Hazardous Materials
DOI 10.1016/j.jhazmat.2023.131007
Open this paper in CoChat — free account

Abstract

Six-carbon-chained polyfluoroalkyl substances, such as 6:2 fluorotelomer alcohol (6:2 FTOH), are being used to replace longer chained compounds in the manufacture of various commercial products. This study examined the effects of growth substrates and nutrients on specific intracellular and extracellular enzymes mediating 6:2 FTOH aerobic biotransformation by the white-rot fungus, Phanerochaete chrysosporium. Cellulolytic conditions with limited glucose were a suitable composition, resulting in high 5:3 FTCA yield (37 mol%), which is a key intermediate in 6:2 FTOH degradation without forming significant amounts of terminal perfluorocarboxylic acids (PFCAs). Sulfate and ethylenediaminetetraacetic acid (EDTA) were also essential for 5:3 FTCA production, but, at lower levels, resulted in the buildup of 5:2 sFTOH (52 mol%) and 6:2 FTUCA (20 mol%), respectively. In non-ligninolytic nutrient-rich medium, 45 mol% 6:2 FTOH was transformed but produced only 12.7 mol% 5:3 FTCA. Enzyme activity studies imply that cellulolytic conditions induce the intracellular cytochrome P450 system. In contrast, extracellular peroxidase synthesis is independent of 6:2 FTOH exposure. Gene expression studies further verified that peroxidases were relevant in catalyzing the downstream transformations from 5:3 FTCA. Collectively, the identification of nutrients and enzymatic systems will help elucidate underlying mechanisms and biogeochemical conditions favorable for fungal transformation of PFCA precurso…

Overview

Integrity signals

Registry

Crossref · 10.1016/j.jhazmat.2023.131007

Cites

3 of 3 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 3 references

Research works printed but not linked: 37

  1. Shaw, 2019, Degradation and defluorination of 6:2 fluorotelomer sulfonamidoalkyl betaine and 6:2 fluorotelomer sulfonate by Gordonia sp. strain NB4-1Y under sulfur-limiting conditions, Sci Total Environ, 647, 690, 10.1016/j.scitotenv.2018.08.012 · DOI · Paper page
  2. Cheng, 2022, Bioaccumulation and biomagnification of emerging poly- and perfluoroalkyl substances in marine organisms, Sci Total Environ, 10.1016/j.scitotenv.2022.158117 · DOI
  3. Rice, 2020, Comparative analysis of the toxicological databases for 6:2 fluorotelomer alcohol (6:2 FTOH) and perfluorohexanoic acid (PFHxA), Food Chem Toxicol, 138, 10.1016/j.fct.2020.111210 · DOI
  4. Butt, 2014, Biotransformation pathways of fluorotelomer-based polyfluoroalkyl substances: a review, Environ Toxicol Chem, 33, 243, 10.1002/etc.2407 · DOI · Paper page
  5. Beškoski, 2018, Defluorination of perfluoroalkyl acids is followed by production of monofluorinated fatty acids, Sci Total Environ, 636, 355, 10.1016/j.scitotenv.2018.04.243 · DOI
  6. Yu, 2020, Microbial cleavage of C-F bonds in Two C6 Per- and polyfluorinated compounds via reductive defluorination, Environ Sci Technol, 54, 14393, 10.1021/acs.est.0c04483 · DOI · Paper page
  7. Kim, 2014, 6:2 Fluorotelomer alcohol (6:2 FTOH) biodegradation by multiple microbial species under different physiological conditions, Appl Microbiol Biotechnol, 98, 1831, 10.1007/s00253-013-5131-3 · DOI · Paper page
  8. Kim, 2012, Biodefluorination and biotransformation of fluorotelomer alcohols by two alkane-degrading Pseudomonas strains, Biotechnol Bioeng, 109, 3041, 10.1002/bit.24561 · DOI · Paper page
  9. Tseng, 2014, Biotransformation of 6:2 Fluorotelomer Alcohol (6:2 FTOH) by A Wood-Rotting Fungus, Environ Sci Technol, 48, 4012, 10.1021/es4057483 · DOI · Paper page
  10. Harms, 2011, Untapped potential: exploiting fungi in bioremediation of hazardous chemicals, Nat Rev Microbiol, 9, 177, 10.1038/nrmicro2519 · DOI · Paper page
  11. Tien, 1988, Lignin peroxidase of Phanerochaete chrysosporium, Methods Enzym, 161, 238, 10.1016/0076-6879(88)61025-1 · DOI
  12. Yadav, 2006, P450ome of the white rot fungus Phanerochaete chrysosporium: structure, evolution and regulation of expression of genomic P450 clusters, Biochem Soc Trans, 34, 1165, 10.1042/BST0341165 · DOI
  13. Gao, 2022, Immobilized fungal enzymes: Innovations and potential applications in biodegradation and biosynthesis, Biotechnology Advances, 57, 107936, 10.1016/j.biotechadv.2022.107936 · DOI
  14. Daramola, 2021, Emerging investigator series: human CYP2A6 catalyzes the oxidation of 6:2 fluorotelomer alcohol, Environ Sci Process Impacts, 23, 1688, 10.1039/D1EM00307K · DOI
  15. Khan, 2022, Fluorotelomer alcohols are efficiently biotransformed by Cunninghamella elegans, Environ Sci Pollut Res, 1, 1
  16. Subramanian, 2009, Role of P450 monooxygenases in the degradation of the endocrine-disrupting chemical nonylphenol by the white rot fungus Phanerochaete chrysosporium, Appl Environ Microbiol, 75, 5580, 10.1128/AEM.02942-08 · DOI
  17. Ning, 2012, Involvement of Cytochrome P450 in pentachlorophenol transformation in a white rot fungus Phanerochaete chrysosporium, PLoS One, 7, 10.1371/journal.pone.0045887 · DOI
  18. Xie, 2022, Pseudomonas sp. strain 273 incorporates organofluorine into the lipid bilayer during growth with fluorinated alkanes, Environ Sci Technol, 56, 8155, 10.1021/acs.est.2c01454 · DOI
  19. Liu, 2010, 6-2 Fluorotelomer alcohol aerobic biodegradation in soil and mixed bacterial culture, Chemosphere, 78, 437, 10.1016/j.chemosphere.2009.10.044 · DOI
  20. Merino, 2018, Fungal biotransformation of 6:2 fluorotelomer alcohol, Remediat J, 28, 59, 10.1002/rem.21550 · DOI
  21. Zhao, 2013, 6:2 Fluorotelomer alcohol biotransformation in an aerobic river sediment system, Chemosphere, 90, 203, 10.1016/j.chemosphere.2012.06.035 · DOI
  22. Zhao, 2013, 6:2 Fluorotelomer alcohol aerobic biotransformation in activated sludge from two domestic wastewater treatment plants, Chemosphere, 92, 464, 10.1016/j.chemosphere.2013.02.032 · DOI · Paper page
  23. Zacchi, 2000, Metabolism of cellulose by Phanerochaete chrysosporium in continuously agitated culture is associated with enhanced production of lignin peroxidase, J Biotechnol, 78, 185, 10.1016/S0168-1656(00)00209-1 · DOI
  24. Ray, 2012, Phanerochaete chrysosporium produces a diverse array of extracellular enzymes when grown on sorghum, Appl Microbiol Biotechnol, 93, 2075, 10.1007/s00253-012-3907-5 · DOI
  25. Žifčáková, 2012, Fungal polysaccharide monooxygenases: new players in the decomposition of cellulose, Fungal Ecol, 5, 481, 10.1016/j.funeco.2012.05.001 · DOI
  26. Meux, 2011, Glutathione Transferases of Phanerochaete chrysosporium, J Biol Chem, 286, 9173, 10.1074/jbc.M110.194548 · DOI
  27. Bucheli-Witschel, 2001, Environmental fate and microbial degradation of aminopolycarboxylic acids, FEMS Microbiol Rev, 25, 69, 10.1111/j.1574-6976.2001.tb00572.x · DOI
  28. Anderson, 1985, A review of the environmental and mammalian toxicology of nitrilotriacetic acid, Crit Rev Toxicol, 15, 1, 10.3109/10408448509023766 · DOI
  29. Schneider-Poetsch, 2010, Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin, Nat Chem Biol, 6, 209, 10.1038/nchembio.304 · DOI
  30. Wang, 2012, 5:3 Polyfluorinated acid aerobic biotransformation in activated sludge via novel “one-carbon removal pathways, Chemosphere, 87, 527, 10.1016/j.chemosphere.2011.12.056 · DOI · Paper page
  31. Yang, 2022, Desulfonation and defluorination of 6:2 fluorotelomer sulfonic acid (6:2 FTSA) by Rhodococcus jostii RHA1: carbon and sulfur sources, enzymes, and pathways, J Hazard Mater, 423, 10.1016/j.jhazmat.2021.127052 · DOI · Paper page
  32. Yan, 2022, Biotransformation of 8:2 fluorotelomer alcohol in soil from aqueous film-forming foams (AFFFs)-impacted sites under nitrate-, sulfate-, and iron-reducing conditions, Environ Sci Technol, 56, 13728, 10.1021/acs.est.2c03669 · DOI
  33. Lin, 2022, Bioremediation of organic pollutants by white rot fungal cytochrome P450: The role and mechanism of CYP450 in biodegradation, Chemosphere, 301, 10.1016/j.chemosphere.2022.134776 · DOI
  34. Doddapaneni, 2005, Microarray-based global differential expression profiling of P450 monooxygenases and regulatory proteins for signal transduction pathways in the white rot fungus Phanerochaete chrysosporium, Mol Genet Genom, 274, 454, 10.1007/s00438-005-0051-2 · DOI
  35. Guengerich, 2009, Measurement of cytochrome P450 and NADPH-cytochrome P450 reductase, Nat Protoc, 4, 1245, 10.1038/nprot.2009.121 · DOI
  36. Durairaj, 2022, Functional expression and regulation of eukaryotic cytochrome P450 enzymes in surrogate microbial cell factories, Eng Microbiol, 2, 10.1016/j.engmic.2022.100011 · DOI
  37. Deroy, 2015, The GSTome reflects the chemical environment of white-rot fungi, PLoS One, 10, 10.1371/journal.pone.0137083 · DOI

Cited by

Sorted by citations

Metadata

Authors
Merino, N., Wang, N., Gao, Y., Wang, M., & Mahendra, S.
ORCID
Venue
Journal of Hazardous Materials
Publisher
Elsevier BV
Published
2023-05
Volume
450
Pages
131007
ISSN
0304-3894
DOI
10.1016/j.jhazmat.2023.131007
Cited by
31
References
3
Language
en
Licence
Funders
  • DuPont de Nemours Inc
  • Air Force Civil Engineer Center (8903\u201311-C-8009)
  • University of California Los Angeles
  • National Science Foundation (1255021, 0963183, 10RR024605)
  • US Environmental Protection Agency

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review