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Cited by 336

The DOI matches its Crossref record; 123 of the 123 references it cites were found in a registry or an index.

Type A viral hepatitis: A summary and update on the molecular virology, epidemiology, pathogenesis and prevention

Open access
Lemon, Stanley M., Ott, Jördis J., Van Damme, Pierre, Shouval, Daniel·2018·Journal of Hepatology

Abstract

Although epidemic jaundice was well known to physicians of antiquity, it is only in recent years that medical science has begun to unravel the origins of hepatitis A virus (HAV) and the unique pathobiology underlying acute hepatitis A in humans. Improvements in sanitation and the successful development of highly efficacious vaccines have markedly reduced the worldwide prevalence and incidence of this enterically-transmitted infection over the past quarter century, yet the virus persists in vulnerable populations and remains a common cause of food-borne disease outbreaks in economically-advantaged societies. Reductions in the prevalence of HAV have led to increases in the median age at which infection occurs, often resulting in more severe disease in affected persons and paradoxical increases in disease burden in some developing nations. Here, we summarize recent advances in the molecular virology of HAV, an atypical member of the Picornaviridae family, survey what is known of the pathogenesis of hepatitis A in humans and the host-pathogen interactions that typify the infection, and review medical and public health aspects of immunisation and disease prevention.

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Metadata

Authors
Lemon, S. M., Ott, J. J., Van Damme, P., & Shouval, D.
Venue
Journal of Hepatology
Publisher
Elsevier BV
Published
2018-01
Volume
68
Issue
1
Pages
167-184
ISSN
0168-8278 (ISSN-L)
OpenAlex
W2753835363
Cited by
336
References
123
FWCI
15.86
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Type A viral hepatitis: A summary and update on the molecular virology, epidemiology, pathogenesis and prevention. https://app.cochat.ai/papers/10.1016/j.jhep.2017.08.034
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Lemon, S. M., Ott, J. J., Van Damme, P., & Shouval, D. (2018). Type A viral hepatitis: A summary and update on the molecular virology, epidemiology, pathogenesis and prevention. Journal of Hepatology. https://doi.org/10.1016/j.jhep.2017.08.034

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.