The DOI matches its Crossref record; 144 of the 144 references it cites were found in a registry or an index.
NAFLD as a driver of chronic kidney disease
Abstract
Non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) are worldwide public health problems, affecting up to 25-30% (NAFLD), and up to 10-15% (CKD) of the general population. Recently, it has also been established that there is a strong association between NAFLD and CKD, regardless of the presence of potential confounding diseases such as obesity, hypertension and type 2 diabetes. Since NAFLD and CKD are both common diseases that often occur alongside other metabolic conditions, such as type 2 diabetes or metabolic syndrome, elucidating the relative impact of NAFLD on the risk of incident CKD presents a substantial challenge for investigators working in this research field. A growing body of epidemiological evidence suggests that NAFLD is an independent risk factor for CKD and recent evidence also suggests that associated factors such as metabolic syndrome, dysbiosis, unhealthy diets, platelet activation and processes associated with ageing could also contribute mechanisms linking NAFLD and CKD. This narrative review provides an overview of the literature on: a) the evidence for an association and causal link between NAFLD and CKD and b) the underlying mechanisms by which NAFLD (and factors strongly linked with NAFLD) may increase the risk of developing CKD.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Still, there is uncertainty as to whether there is a direct causal link between MASLD and CKD as both diseases share common risk factors. 227”
From EASL-EASD-EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD). (2024) · cites this paper as [227]
Citations
Cites
Alberti, K. G. M. M., Eckel, R. H., Grundy, S. M., Zimmet, P. Z., Cleeman, J. I., Donato, K. A., Fruchart, J.-C., James, W. P. T., Loria, C. M., & Smith, S. C. (2009) · Circulation · doi:10.1161/circulationaha.109.192644 · Cited by 14,860
KDIGO 2024 clinical practice guideline for the evaluation and management of chronic kidney disease
Stevens, P. E., Ahmed, S. B., Carrero, J. J., Foster, B., Francis, A., Hall, R. K., Herrington, W. G., Hill, G., Inker, L. A., Kazancıoğlu, R., et al. (2024) · Kidney International · doi:10.1016/j.kint.2023.10.018 · Cited by 8,530
Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention
Younossi, Z., Anstee, Q. M., Marietti, M., Hardy, T., Henry, L., Eslam, M., George, J., & Bugianesi, E. (2018) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2017.109 · Cited by 5,249
Prevalence of Chronic Kidney Disease in the United States
Coresh, J., Selvin, E., Stevens, L. A., Manzi, J., Kusek, J. W., Eggers, P., Van Lente, F., & Levey, A. S. (2007) · JAMA · doi:10.1001/jama.298.17.2038 · Cited by 4,895
EASL–EASD–EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease
(2016) · Journal of Hepatology · doi:10.1016/j.jhep.2015.11.004 · Cited by 4,836
Levey, A. S., Coresh, J., Balk, E., Kausz, A. T., Levin, A., Steffes, M. W., Hogg, R. J., Perrone, R. D., Lau, J., & Eknoyan, G. (2003) · Annals of Internal Medicine · doi:10.7326/0003-4819-139-2-200307150-00013 · Cited by 4,615
Global Prevalence of Chronic Kidney Disease – A Systematic Review and Meta-Analysis
Hill, N. R., Fatoba, S., Oke, J. L., Hirst, J. A., O’Callaghan, C. A., Lasserson, D. S., & Hobbs, R. F. (2016) · PLoS ONE · doi:10.1371/journal.pone.0158765 · Cited by 4,320
Donnelly, K. L., Smith, C. I., Schwarzenberg, S. J., Jessurun, J., Boldt, M. D., & Parks, E. J. (2005) · Journal of Clinical Investigation · doi:10.1172/jci23621 · Cited by 3,604
Byrne, C. D., & Targher, G. (2015) · Journal of Hepatology · doi:10.1016/j.jhep.2014.12.012 · Cited by 3,162
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
Cai, D., Yuan, M., Frantz, D. F., Melendez, P. A., Hansen, L., Lee, J., & Shoelson, S. E. (2005) · Nature Medicine · doi:10.1038/nm1166 · Cited by 2,245
Flagged first, then by citations
Cited by
Sorted by citations
Items 101–200 of 449
Zuo, G., Xuan, L., Xin, Z., Xu, Y., Lu, J., Chen, Y., Dai, M., Zhang, D., Wang, W., Li, M., et al. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab425 · Cited by 29
Zhou, J., Sun, D., Targher, G., Byrne, C. D., Lee, B., Hamaguchi, M., Kim, S. U., Hou, X., Fadini, G. P., Shimabukuro, M., et al. (2023) · eGastroenterology · doi:10.1136/egastro-2023-100005 · Cited by 27
Mai, Z., Chen, Y., Mao, H., & Wang, L. (2024) · Journal of Diabetes · doi:10.1111/1753-0407.13569 · Cited by 30
Ma, X., Ji, B., Du, W., Shi, S., Zhao, H., Sheng, J., Jiang, X., Ban, B., & Gao, G. (2024) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s476398 · Cited by 26
Bioactive metabolites: A clue to the link between MASLD and CKD?
Chen, W., Zhang, J.-H., Chen, L., Byrne, C. D., Targher, G., Luo, L., Ni, Y., Zheng, M., & Sun, D. (2024) · Clinical and Molecular Hepatology · doi:10.3350/cmh.2024.0782 · Cited by 27
Advance of Serum Biomarkers and Combined Diagnostic Panels in Nonalcoholic Fatty Liver Disease
Zeng, Y., He, H., & An, Z. (2022) · Disease Markers · doi:10.1155/2022/1254014 · Cited by 27
Su, W., Chen, M., Xiao, L., Du, S., Xue, L., Feng, R., & Ye, W. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.1047794 · Cited by 27
Mazzini, F. N., Cook, F., Gounarides, J., Marciano, S., Haddad, L., Tamaroff, A. J., Casciato, P. C., Narvaez, A., Mascardi, M. F., Anders, M., et al. (2021) · Metabolomics · doi:10.1007/s11306-021-01810-6 · Cited by 26
The Inter-Organ Crosstalk Reveals an Inevitable Link between MAFLD and Extrahepatic Diseases
Tsutsumi, T., Nakano, D., Hashida, R., Sano, T., Kawaguchi, M., Amano, K., & Kawaguchi, T. (2023) · Nutrients · doi:10.3390/nu15051123 · Cited by 28
Cen, J., Han, Y. Y., Liu, Y., & Hu, H. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.916704 · Cited by 24
Cazanave, S. C., Warren, A. D., Pacula, M., Touti, F., Zagorska, A., Gural, N., Huang, E. K., Sherman, S., Cheema, M., Ibarra, S., et al. (2021) · Science Translational Medicine · doi:10.1126/scitranslmed.abe8939 · Cited by 23
Bilson, J., Hydes, T., McDonnell, D., Buchanan, R. M., Scorletti, E., Mantovani, A., Targher, G., & Byrne, C. D. (2024) · Liver International · doi:10.1111/liv.16159 · Cited by 27
Leslie, J., Krishnamurthy, K. A., Gopalsamy, I. K., Inácio, P., Huch, M., Gallage, S., Oakley, F., & Vacca, M. (2026) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-025-01162-9 · Cited by 27
Bile acid signaling in MASLD: From pathogenesis to therapeutic applications
Simbrunner, B., Paternostro, R., Reiberger, T., & Trauner, M. (2025) · Hepatology · doi:10.1097/hep.0000000000001539 · Cited by 30
Sun, Y., Hong, L., Huang, Z., Wang, L., Xiong, Y., Zong, S., Zhang, R., Liu, J., & Zang, S. (2022) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgac382 · Cited by 24
Advancements in MAFLD Modeling with Human Cell and Organoid Models
Wang, S.-X., Yan, J.-S., & Chan, Y.-S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911850 · Cited by 22
Anari, M., & Montgomery, M. K. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115621 · Cited by 24
Liver stiffness as a cornerstone in heart disease risk assessment
Boeckmans, J., Sandrin, L., Knackstedt, C., & Schattenberg, J. M. (2023) · Liver International · doi:10.1111/liv.15801 · Cited by 24
Chrysavgis, L., Kazanas, S., Bafa, K., Rozani, S., Koloutsou, M. E., & Cholongitas, Ε. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25073832 · Cited by 26
Chen, Q., Zhu, Y., Gao, J., Ni, W., Liu, S., Rui, F., Bai, X., Geng, N., Jin, R., Sun, Y., et al. (2025) · Communications Medicine · doi:10.1038/s43856-025-01195-w · Cited by 22
Perdomo, C. M., Garcı́a-Fernández, N., & Escalada, J. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10092040 · Cited by 21
Li, S., Wu, Y., Jiang, H., Zhou, F., Ben, A., Wang, R., & Hua, C. (2022) · Food Science and Human Wellness · doi:10.1016/j.fshw.2022.03.025 · Cited by 21
Zhang, Y., & Fang, X.-M. (2023) · The Chinese Journal of Physiology · doi:10.4103/cjop.cjop-d-22-00131 · Cited by 22
Kanbay, M., Bulbul, M. C., Çopur, S., Afşar, B., Sag, A., Siriopol, D., Kuwabara, M., Bădărau, S., Covic, A., & Ortiz, A. (2020) · JN. Journal of Nephrology (Milano. 1992) · doi:10.1007/s40620-020-00751-y · Cited by 23
Dissayabutra, T., Chuaypen, N., Somnark, P., Boonkaew, B., Udomkarnjananun, S., Kittiskulnam, P., Charoenchittang, P., Prombutara, P., & Tangkijvanich, P. (2025) · Scientific Reports · doi:10.1038/s41598-025-00237-6 · Cited by 23
Moncho, F., Benlloch, S., & Górriz, J. L. (2025) · Clinical Kidney Journal · doi:10.1093/ckj/sfaf260 · Cited by 25
Outcomes After TIPS for Ascites and Variceal Bleeding in a Contemporary Era—An ALTA Group Study
Boike, J. R., Mazumder, N. R., Kolli, K. P., Ge, J., German, M. N., Jest, N., Morelli, G., Spengler, E. K., Said, A., Lai, J. C., et al. (2021) · The American Journal of Gastroenterology · doi:10.14309/ajg.0000000000001357 · Cited by 20
Boulos, M., Mousa, R. S., Jeries, N., Simaan, E., Alam, K., Bulus, B., & Assy, N. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26073448 · Cited by 22
Sharma, M., Singh, V., Sharma, R., Koul, A., McCarthy, E. T., Savin, V. J., Joshi, T., & Srivastava, T. (2022) · Biomedicines · doi:10.3390/biomedicines10020407 · Cited by 19
Perakakis, N., Bornstein, S. R., Birkenfeld, A. L., Linkermann, A., Demir, M., Anker, S. D., Filippatos, G. S., Pitt, B., Rossing, P. R., Ruilope, L. M., et al. (2023) · Diabetes Obesity and Metabolism · doi:10.1111/dom.15305 · Cited by 20
Adinolfi, L. E., Marrone, A., Rinaldi, L., Nevola, R., Izzi, A., & Sasso, F. C. (2025) · Exploration of Medicine · doi:10.37349/emed.2025.1001281 · Cited by 18
Targeting gut–liver–kidney axis: microbiota-derived metabolites and therapeutic implications
Zhang, Y., Sun, C., Wang, Y., Zhang, H., Fan, Y., Zhao, H., & Li, P. (2026) · Cell Communication and Signaling · doi:10.1186/s12964-025-02625-x · Cited by 19
Hamada, S., Takata, T., Yamada, K., Yamamoto, M., Mae, Y., Iyama, T., Ikeda, S., Kanda, T., Sugihara, T., & Isomoto, H. (2022) · PLoS ONE · doi:10.1371/journal.pone.0265461 · Cited by 18
Gellert‐Kristensen, H., Tybjærg‐Hansen, A., Nordestgaard, B. G., Ghouse, J., Fuchs, A., Kühl, J. T., Sigvardsen, P. E., Kofoed, K. F., & Stender, S. (2023) · Liver International · doi:10.1111/liv.15629 · Cited by 19
Xing, M., Ni, Y., Zhang, Y., Zhao, X., & Yu, X. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1246157 · Cited by 23
Sun, D., Wang, T.-Y., Zheng, K. I., Zhang, H., Wang, X., Targher, G., Byrne, C. D., Chen, Y., Yuan, W., Jin, Y. J., et al. (2021) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2021.02.018 · Cited by 18
The Interplay Between Nonalcoholic Fatty Liver Disease and Kidney Disease
Truong, E., & Noureddin, M. (2022) · Clinics in Liver Disease · doi:10.1016/j.cld.2022.01.008 · Cited by 17
Nonalcoholic Fatty Liver Disease as a Systemic Disease and the Need for Multidisciplinary Care
Yoneda, M., Kobayashi, T., Iwaki, M., Nogami, A., Saito, S., & Nakajima, A. (2023) · Gut and Liver · doi:10.5009/gnl220545 · Cited by 17
Heo, J. H., Lee, M. Y., Kim, S. H., Zheng, M., Byrne, C. D., Targher, G., & Sung, K. (2024) · HepatoBiliary Surgery and Nutrition · doi:10.21037/hbsn-23-558 · Cited by 17
Aubert, L., Sandino, J., Gutiérrez-Solís, E., García-Martín, F., Segura, J., Porrini, E., & Morales, E. (2021) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfab176 · Cited by 17
Hou, C., Yuan, X., Peng, M., Shi, X., Yang, D., Wang, F., Song, K., Xu, G., & Shi, J. (2025) · Cardiovascular Diabetology · doi:10.1186/s12933-025-02953-9 · Cited by 16
Kim, H., Lee, M., Lee, Y., Kang, E. S., Soo, B., & Lee, B. (2021) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2020.0273 · Cited by 16
Chung, G. E., Han, K., Lee, K., Cho, E. J., Bae, J., Yang, S.-Y., Yu, S.-J., Choi, S., Yim, J.-Y., & Heo, N.-J. (2022) · Biomedicines · doi:10.3390/biomedicines10061245 · Cited by 19
Chang, K., Li, Y., Qin, Z., Zhang, Z., Wang, L., Yang, Q., & Su, B. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12020637 · Cited by 16
Li, H., Miao, X., Zhong, J., & Zhu, Z. (2024) · Clinical Medicine Insights Endocrinology and Diabetes · doi:10.1177/11795514241259741 · Cited by 16
Sumida, Y., Yoneda, M., Toyoda, H., Yasuda, S., Tada, T., Hayashi, H., Nishigaki, Y., Suzuki, Y., Naiki, T., Morishita, A., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21144939 · Cited by 16
Human and molecular genetics shed lights on fatty liver disease and diabetes conundrum
Tavaglione, F., Targher, G., Valenti, L. V. C., & Romeo, S. (2020) · Endocrinology Diabetes & Metabolism · doi:10.1002/edm2.179 · Cited by 15
A novel quantitative ultrasound technique for identifying non‐alcoholic steatohepatitis
Gao, F., He, Q., Li, G., Huang, O., Tang, L., Wang, X., Targher, G., Byrne, C. D., Luo, J., & Zheng, M. (2021) · Liver International · doi:10.1111/liv.15064 · Cited by 16
Incidence of chronic kidney disease in patients with non-alcoholic fatty liver disease
Zou, Z., & Fan, J. (2020) · Journal of Hepatology · doi:10.1016/j.jhep.2020.03.003 · Cited by 16
Integrated Patient Digital and Biomimetic Twins for Precision Medicine: A Perspective
Miedel, M. T., Schurdak, M. E., Stern, A. M., Soto–Gutiérrez, A., Strobl, E. V., Behari, J., & Taylor, D. L. (2025) · Seminars in Liver Disease · doi:10.1055/a-2649-1560 · Cited by 20
Kotoku, K., Michishita, R., Matsuda, T., Kawakami, S., Morito, N., Uehara, Y., & Higaki, Y. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18136980 · Cited by 15
Park, S., Lee, S., Kim, Y., Cho, S., Kim, K., Kim, Y. C., Han, S. S., Lee, H., Lee, J. P., Joo, K. W., et al. (2021) · Liver International · doi:10.1111/liv.15118 · Cited by 15
Zou, Y., Zhao, L., Zhang, J., Wang, Y., Wu, Y., Ren, H., Wang, T., Zhao, Y., Xu, H., Li, L., et al. (2022) · Acta Diabetologica · doi:10.1007/s00592-022-01978-w · Cited by 15
Corbin, K. D., Dagogo-Jack, S. E., Cannon, C. P., Cherney, D. Z. I., Cosentino, F., Frederich, R. C., Liu, J., Pong, A., Lin, J., Cater, N. B., et al. (2022) · Diabetes Obesity and Metabolism · doi:10.1111/dom.14923 · Cited by 17
Tsamos, G., Vasdeki, D., Koufakis, T., Michou, V., Makedou, K., & Tzimagiorgis, G. (2023) · Metabolites · doi:10.3390/metabo13040517 · Cited by 16
Wu, Z., Xiao, H., Rao, D. R., Wang, J., Lv, X., Wang, D., Yao, P., Huang, F., Chen, H., & Wei, F. (2023) · Analytical Chemistry · doi:10.1021/acs.analchem.3c02789 · Cited by 15
Zhang, W., Song, W. J., Chen, W., Pan, Z., Zhang, J., Fan, L., & Li, J. (2024) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000002767 · Cited by 18
Wang, M., Zhang, R., Wang, M., Zhang, L., Ding, Y., Tang, Z., Wang, H., Zhang, W., Chen, Y., & Wang, J. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.717533 · Cited by 14
Лазебник, Л. Б., & Туркина, С. В. (2021) · Экспериментальная и клиническая гастроэнтерология · doi:10.31146/1682-8658-ecg-194-10-5-13 · Cited by 14
Cyclo(His-Pro): A further step in the management of steatohepatitis
Masi, A. D., Li, X., Lee, D., Jeon, J., Wang, Q., Baek, S., Park, O., Mottis, A., Strotjohann, K., Rapin, A., et al. (2023) · JHEP Reports · doi:10.1016/j.jhepr.2023.100815 · Cited by 14
Kosmalski, M., Frankowski, R., Deska, K., Różycka-Kosmalska, M., & Pietras, T. (2023) · Nutrients · doi:10.3390/nu15132838 · Cited by 15
Wongtrakul, W., Charatcharoenwitthaya, N., & Charatcharoenwitthaya, P. (2024) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000002719 · Cited by 14
Asrani, S. K., Hall, L., Reddy, V., Ogola, G., & Izzy, M. J. (2022) · The American Journal of Gastroenterology · doi:10.14309/ajg.0000000000001909 · Cited by 16
Bogdan, R. G., Boicean, A., Anderco, P., Ichim, C., Iliescu-Glaja, M., Todor, S. B., Leonte, E., Bloancă, V., Crăiniceanu, Z. P., & Popa, M. L. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14072486 · Cited by 19
Yang, W., Jin, Q., Xiao, D., Li, X., & Huang, D. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1597995 · Cited by 13
Huang, L., Bai, Q., Wang, Z., Zhang, X., Liu, K., Cui, J., Du, L., Liu, S., Fu, Y., Wang, H., et al. (2023) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.3c00362 · Cited by 13
Greco, S., Campigotto, M., D’Amuri, A., Fabbri, N., & Passaro, A. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13092714 · Cited by 15
Fan, Y.-Q., Wang, H., Wang, P., Shi, Z.-Y., Wang, Y., & Xu, J. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1501494 · Cited by 14
Yang, C., Wu, S., Lan, Y., Chen, S., Zhang, D., Wang, Y., Sun, Y., Liao, W., & Wang, L. (2023) · Biological Trace Element Research · doi:10.1007/s12011-022-03543-6 · Cited by 13
Gao, F., Zheng, K. I., Chen, S., Lee, D. H., Wu, X.-X., Wang, X.-D., Targher, G., Byrne, C. D., Chen, Y.-P., Kim, W. K., et al. (2021) · Clinical and Translational Gastroenterology · doi:10.14309/ctg.0000000000000321 · Cited by 15
Supriyadi, R., Yanto, T. A., Hariyanto, T. I., & Suastika, K. (2023) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2023.102814 · Cited by 12
Renal impairment is prevalent in pediatric NAFLD/MASLD and associated with disease severity
Mouzaki, M., Yates, K. P., Arce‐Clachar, A. C., Behling, C., Blondet, N. M., Fishbein, M. H., Flores, F., Adams, K. H., Hertel, P. M., Jain, A. K., et al. (2024) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1002/jpn3.12272 · Cited by 13
Lv, D., Han, N., Yuan, M., Huang, W., Yan, L., & Tang, H. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.08.189 · Cited by 12
Organ damage proteomic signature identifies patients with MASLD at risk of systemic complications
Pirola, C. J., Diambra, L. A., Gianotti, T. F., Castaño, G. O., Martino, J. S., Garaycoechea, M. E., & Sookoian, S. C. (2025) · Hepatology · doi:10.1097/hep.0000000000001346 · Cited by 13
Alipour, M. R., Jeddi, S., & Karimi‐Sales, E. (2020) · Journal of Food Biochemistry · doi:10.1111/jfbc.13476 · Cited by 12
Nonalcoholic Fatty Liver Disease-Related Chronic Kidney Disease
Cojocariu, C., Sîngeap, A.-M., Gîrleanu, I., Chiriac, S. A., Muzica, C. M., Sfarti, C. V., Cuciureanu, T., Huiban, L., Stanciu, C., & Trifan, A. V. (2020) · Canadian Journal of Gastroenterology and Hepatology · doi:10.1155/2020/6630296 · Cited by 12
NAFLD and renal function in children: is there a genetic link?
Sessa, A. D., Guarino, S., Passaro, A. P., Liguori, L., Umano, G. R., Cirillo, G., del Giudice, E. M., & Marzuillo, P. (2021) · Expert Review of Gastroenterology & Hepatology · doi:10.1080/17474124.2021.1906649 · Cited by 12
Taheri, E., Moslem, A., Mousavi-Jarrahi, A., Hatami, B., Pourhoseingholi, M. A., Aghdaei, H. A., & Zali, M. R. (2021) · Gastroenterology and hepatology from bed to bench. · Cited by 12
Is there a place for faecal microbiota transplantation in chronic kidney disease?
Benech, N., & Koppe, L. (2022) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfac277 · Cited by 12
Han, E., Kim, M. K., Im, S., Jang, B. K., & Kim, H. S. (2022) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2022.108253 · Cited by 12
A nutrigenetic precision approach for the management of non-alcoholic fatty liver disease
Pérez-Díaz-del-Campo, N., Dileo, E., Castelnuovo, G., Nicolosi, A., Guariglia, M., Caviglia, G. P., Rosso, C., Armandi, A., & Bugianesi, E. (2023) · Clinical Nutrition · doi:10.1016/j.clnu.2023.09.022 · Cited by 11
Björnsdóttir, S., Ulfsdottir, H., Gudmundsson, E. F., Sveinsdottir, K., Ísberg, A. P., Dobies, B., Magnusdottir, G. E. A., Gunnarsdottir, T., Karlsdottir, T., Björnsdóttir, G., et al. (2023) · JMIR Cardio · doi:10.2196/52576 · Cited by 12
Lee, H. H., Ro, H., Jung, J. Y., Chang, J. H., Chung, W., & Kim, A. J. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13061616 · Cited by 11
Association of fatty liver index with sudden cardiac arrest in young adults
Jeong, J. H., Kim, Y. G., Han, K.-D., Roh, S., Lee, H. S., Choi, Y. Y., Yim, S. Y., Shim, J., Kim, Y., & Choi, J. (2024) · Metabolism · doi:10.1016/j.metabol.2024.155981 · Cited by 12
Circulating ANGPTL8 levels and risk of kidney function decline: Results from the 4C Study
Zou, H., Xu, Y., Meng, X., Li, D., Chen, X., Du, T., Yang, Y., Chen, Y., Shao, S., Yuan, G., et al. (2021) · Cardiovascular Diabetology · doi:10.1186/s12933-021-01317-3 · Cited by 11
Reinson, T., Byrne, C. D., Patel, J., El-Gohary, M., & Moore, M. V. (2021) · BJGP Open · doi:10.3399/bjgpo.2021.0145 · Cited by 11
Marc, L., Mihăescu, A., Lupușoru, R., Grosu, I. D., Gădălean, F., Bob, F. R., Chisavu, L. A., Olariu, N., Tucicovschi, V., Timar, B., et al. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2021.788881 · Cited by 11
Tao, X., Chen, C., Huang, Z., Yu, L., Wang, M.-R., Wang, S., & Tian, D. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-05792-2 · Cited by 12
Targher, G., & Byrne, C. D. (2020) · Hepatoma Research · doi:10.20517/2394-5079.2020.71 · Cited by 11
What’s Past Is Prologue: History of Nonalcoholic Fatty Liver Disease
Targher, G. (2020) · Metabolites · doi:10.3390/metabo10100397 · Cited by 11
Hu, S., Li, X., Sun, Y., Wu, S., Lan, Y., Chen, S., Wang, Y., Liao, W., Wang, X., Zhang, D., et al. (2022) · Obesity · doi:10.1002/oby.23459 · Cited by 11
Hepato-Renal Crosstalk in Acute and Chronic Disease: From Shared Pathways to Therapeutic Targets
Clementi, A., Virzì, G. M., Sorbello, M., Marzano, N., Monciino, P., Cabrera-Aguilar, J. S., Battaglia, G. G., Ronco, C., & Zanella, M. (2025) · Biomedicines · doi:10.3390/biomedicines13071618 · Cited by 10
Collier, A., Curran, C., Cameron, L., Wild, S. H., & Byrne, C. D. (2023) · Diabetes Obesity and Metabolism · doi:10.1111/dom.15153 · Cited by 10
Sun, C., Goh, G. B., Chow, W. C., Chan, W., Wong, G. L., Seto, W., Huang, Y., Lin, H.-C., Lee, H. W., Lee, H. W., et al. (2023) · Hepatobiliary & pancreatic diseases international · doi:10.1016/j.hbpd.2023.08.004 · Cited by 10
Vujasinović, M., Ebrahimi, F., Roelstraete, B., Bergman, D., Sun, J., Sadr‐Azodi, O., Löhr, M. J., & Ludvigsson, J. F. (2025) · United European Gastroenterology Journal · doi:10.1002/ueg2.12761 · Cited by 10
Liver fibrosis progression analyzed with AI predicts renal decline
Sun, D., Shen, J., Tong, X., Ren, Y., Yuan, H., Li, Y., Wang, X., Chen, S., Zhu, P., Wang, X.-D., et al. (2025) · JHEP Reports · doi:10.1016/j.jhepr.2025.101358 · Cited by 10
Chen, L., Lv, X., Kan, M., Wang, R., Wang, H., & Zang, H. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012464 · Cited by 11
Effective Classification of Chronic Kidney Disease Using Extreme Gradient Boosting Algorithm
Busi, R. A., & Stephen, M. (2023) · International Journal of Software Innovation · doi:10.4018/ijsi.315732 · Cited by 10
Bae, J., & Lee, B. (2023) · Biomedicines · doi:10.3390/biomedicines11071928 · Cited by 10
Sun, M., Li, Y., Su, S., Gao, J., Yu, L., Qi, X., Liang, H., Li, X., Qi, X., Liang, Y., et al. (2023) · Phytotherapy Research · doi:10.1002/ptr.7818 · Cited by 9
Metadata
- Authors
- Byrne, C. D., & Targher, G.
- Affiliations
- University Hospital Southampton NHS Foundation Trust (GB)
- University of Verona (IT)
- Corresponding author
- Byrne, Christopher D.
- Targher, Giovanni
- Venue
- Journal of Hepatology
- Publisher
- Elsevier BV
- Published
- 2020-04
- Volume
- 72
- Issue
- 4
- Pages
- 785-801
- ISSN
- 0168-8278 (ISSN-L)
- OpenAlex
- W3006576880
- Cited by
- 449
- References
- 144
- Citations by year
- 2026: 45 · 2025: 72 · 2024: 76 · 2023: 85 · 2022: 79 · 2021: 57 · 2020: 34
- FWCI
- 9.30
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Hepatology (publishedVersion)
- PubMed (publishedVersion)
- ePrints Soton (University of Southampton) (acceptedVersion)
- Funders
- NIHR Bristol Biomedical Research Centre (IS-BRC-20004)
- Topics
- Health Sciences › Medicine › Hepatology › Liver Disease Diagnosis and Treatment
- Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Keywords
- non-alcoholic fatty liver disease, chronic kidney disease, CKD risk factors, metabolic syndrome, dysbiosis, platelet activation, aging, type 2 diabetes, obesity, hypertension, unhealthy diet, pathophysiological mechanisms
- MeSH terms
- Adolescent, Adult, Aging, Child, Diabetes Mellitus, Type 2, Diet, Female, Humans, Male, Middle Aged, Obesity, Risk Factors, Platelet Activation, Comorbidity, Prevalence, Metabolic Syndrome, Renal Insufficiency, Chronic, Young Adult, Dysbiosis, Non-alcoholic Fatty Liver Disease
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
