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Emerging invasive liver abscess caused by K1 serotype Klebsiella pneumoniae in Korea

Chung, D.R., Lee, S.S., Lee, H.R., Kim, H.B., Choi, H.J., Eom, J.S., Kim, J.S., Choi, Y.H., Lee, J.S., Chung, M.H., Kim, Y.S., Lee, H., Lee, M.S., Park, C.K.·2007·Journal of Infection

Abstract

OBJECTIVES The high incidence of invasive liver abscess caused by Klebsiella pneumoniae in Taiwan, contrasted with the rareness of this disease in Western countries, has aroused special interest. There have been few detailed reports from other Asian countries. To investigate a current epidemiology of K. pneumoniae liver abscess in Korea and to determine K serotype distribution in K. pneumoniae strains causing liver abscess, we performed a nationwide prospective study. METHODS Community-acquired, culture-proven liver abscess cases were enrolled between 2004 and 2005. Etiologies and clinical features were analyzed. K. pneumoniae isolates were serotyped according to K antigen. Meta-analysis was done to determine the time trend of the etiologies of liver abscess in Korea. RESULTS Out of 371 cases collected prospectively, 290 (78.2%) were caused by K. pneumoniae. Most K. pneumoniae liver abscesses were monomicrobial. Diabetes mellitus was the most common underlying disease (39.9%). Distant metastatic infections were frequently observed (8.7%). magA PCR revealed that 95 (59.4%) out of 160 K. pneumoniae isolates belonged to the K1 serotype. CONCLUSIONS Our study indicates that K. pneumoniae has emerged as a major etiologic agent of liver abscess in Korea, and these emerging infections seem to be attributable to invasive K. pneumoniae strains with capsular K1 serotype.

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Metadata

Authors
Chung, D. R., Lee, S. S., Lee, H. R., Kim, H. B., Choi, H. J., Eom, J. S., Kim, J. S., Choi, Y. H., Lee, J. S., Chung, M. H., Kim, Y. S., Lee, H., Lee, M. S., & Park, C. K.
Venue
Journal of Infection
Publisher
Elsevier BV
Published
2007-06
Volume
54
Issue
6
Pages
578-583
ISSN
0163-4453 (ISSN-L)
OpenAlex
W1963494672
Cited by
273
References
17
FWCI
3.82
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Emerging invasive liver abscess caused by K1 serotype Klebsiella pneumoniae in Korea. https://app.cochat.ai/papers/10.1016/j.jinf.2006.11.008
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Chung, D. R., Lee, S. S., Lee, H. R., Kim, H. B., Choi, H. J., Eom, J. S., Kim, J. S., Choi, Y. H., Lee, J. S., Chung, M. H., Kim, Y. S., Lee, H., Lee, M. S., & Park, C. K. (2007). Emerging invasive liver abscess caused by K1 serotype Klebsiella pneumoniae in Korea. Journal of Infection. https://doi.org/10.1016/j.jinf.2006.11.008

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.