The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Large-scale production and purification of VLP-based vaccines
Open accessAbstract
Graphical abstract Relevant strategies implemented to overcome the challenges of large-scale production (USP) and purification (DSP) of VLP-vaccines using the BEVS/IC. These strategies, often used as rationale for other expression systems, are essential to achieve a competitive and effective VLP manufacturing process. Highlights ► One VLP-based vaccine produced in BEVS/IC is in the market and many others are in pre-clinical and clinical stages. ► Added complexity of single and/or multi-protein VLPs poses important bioprocessing challenges. ► Novel modeling tools provide insights to accelerate up- and downstream process development. ► A comprehensive list of analyticals is critical for a streamlined development of a lead VLP-based vaccine.
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Cites
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Cited by
Nooraei, S., Bahrulolum, H., Hoseini, Z. S., Katalani, C., Hajizade, A., Easton, A. J., & Ahmadian, G. (2021) · Journal of Nanobiotechnology · doi:10.1186/s12951-021-00806-7 · Cited by 869
Current challenges in biotherapeutic particles manufacturing
Moleirinho, M. G., Silva, R. J. S., Alves, P. M., Carrondo, M. J. T., & Peixoto, C. (2020) · Expert Opinion on Biological Therapy · doi:10.1080/14712598.2020.1693541 · Cited by 123
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Metadata
- Authors
- Vicente, T., Roldão, A., Peixoto, C., Carrondo, M. J. T., & Alves, P. M.
- Venue
- Journal of Invertebrate Pathology
- Publisher
- Elsevier BV
- Published
- 2011-07
- Volume
- 107
- Pages
- S42-S48
- ISSN
- 0022-2011 (ISSN-L)
- OpenAlex
- W2054243692
- Cited by
- 270
- References
- 34
- FWCI
- 6.23
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Vicente, T., Roldão, A., Peixoto, C., Carrondo, M. J. T., & Alves, P. M. (2011). Large-scale production and purification of VLP-based vaccines. Journal of Invertebrate Pathology. https://doi.org/10.1016/j.jip.2011.05.004
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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