The Intrinsic Contributions of Tyrosine, Serine, Glycine and Arginine to the Affinity and Specificity of Antibodies

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Items 101–200 of 243

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9. Identification and characterization of β-lactamase inhibitor protein-II (BLIP-II) interactions with β-lactamases using phage display
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10. Human antibody polyreactivity is governed primarily by the heavy-chain complementarity-determining regions
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15. Structure-Directed and Tailored Diversity Synthetic Antibody Libraries Yield Novel Anti-EGFR Antagonists
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17. Deep Characterization of the Human Antibody Response to Natural Infection Using Longitudinal Immune Repertoire Sequencing
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19. Mutations in Protein-Binding Hot-Spots on the Hub Protein Smad3 Differentially Affect Its Protein Interactions and Smad3-Regulated Gene Expression
    Michelle M. Schiro, Sara E. Stauber, Tami L. Peterson, Chateen Krueger, Steven J. Darnell, Kenneth A. Satyshur, Norman R. Drinkwater, Michael A. Newton, F. Michael Hoffmann · 2011 · PLoS ONE
20. Biochemical and biophysical characterization of natural polyreactivity in antibodies
    Marta T. Borowska, Christopher T. Boughter, Jeffrey J. Bunker, Jenna J. Guthmiller, Patrick C. Wilson, Benoı̂t Roux, Albert S Bendelac, Erin J. Adams · 2023 · Cell Reports
21. Constrained Combinatorial Libraries of Gp2 Proteins Enhance Discovery of PD-L1 Binders
    Max A. Kruziki, Vidur Sarma, Benjamin J. Hackel · 2018 · ACS Combinatorial Science
22. A Potent Anti-SpuE Antibody Allosterically Inhibits Type III Secretion System and Attenuates Virulence of Pseudomonas Aeruginosa
    Yang Zhang, Xiaodan Sun, Yangyang Qian, Hongfei Yi, Ke Song, Huanhu Zhu, Francesco Zonta, Weizhong Chen, Quanjiang Ji, Shane Miersch et al. · 2019 · Journal of Molecular Biology
23. Use of high-capacity surface with oriented recombinant antibody fragments in a 5-min immunoassay for thyroid-stimulating hormone
    Eeva‐Christine Brockmann, Markus Vehniäinen, Kim S. I. Pettersson · 2009 · Analytical Biochemistry
24. General In Vitro Method to Analyze the Interactions of Synthetic Polymers with Human Antibody Repertoires
    Anandakumar Soshee, Stefan Zürcher, Nicholas D. Spencer, Avraham Halperin, Clément Nizak · 2013 · Biomacromolecules
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    Jessica Mallaby, Joseph Chi-Fung Ng, Alex Stewart, Emma L. Sinclair, Deborah K. Dunn‐Walters, Uri Hershberg · 2022 · Frontiers in Immunology
26. Polyreactivity of antibodies from different B-cell subpopulations is determined by distinct sequence patterns of variable region
    Maxime Lecerf, Robin V. Lacombe, Jordan D. Dimitrov · 2023 · Frontiers in Immunology
27. Streamlining the Pipeline for Generation of Recombinant Affinity Reagents by Integrating the Affinity Maturation Step
    Renhua R. Huang, Kevin Thomas Gorman, Chris R. Vinci, E. Dobrovetsky, S. Gräslund, Brian K. Kay · 2015 · International Journal of Molecular Sciences
28. Synthetic Fab fragments that bind the HIV-1 gp41 heptad repeat regions
    Yanyun Liu, Lauren K. Regula, Alex Stewart, Jonathan R. Lai · 2011 · Biochemical and Biophysical Research Communications
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    Zhenwei Zhong, Yue Yang, Xiaorui Chen, Zhen Han, Jincai Zhou, Bohua Li, Xiaowen He · 2021 · Biochemical and Biophysical Research Communications
30. Molecular Characterization of Monoclonal Antibodies that Inhibit Acetylcholinesterase by Targeting the Peripheral Site and Backdoor Region
    Yves Bourne, Ludovic L. R. Renault, Sosthène Essono, Grégoire Mondielli, Patricia Lamourette, Didier Boquet, Jacques J. Grassi, P. Marchot · 2013 · PLoS ONE
31. Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment
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    Lerna Uzasci, Mario A. Bianchet, Robert J. Cotter, Avindra Nath · 2014 · Journal of Proteome Research
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    Longxing Cao, Brian Coventry, Inna Goreshnik, Buwei Huang, Joon Sung Park, Kevin M. Jude, Iva Marković, Rameshwar U. Kadam, Koen H. G. Verschueren, Kenneth Verstraete et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
36. Prediction of polyspecificity from antibody sequence data by machine learning
    Szabolcs Éliás, Clemens Wrzodek, Charlotte Mary Deane, Alain C. Tissot, Stefan Klostermann, Francesca Ros · 2024 · Frontiers in Bioinformatics
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38. The Use of Phage Display in Neurobiology
    Andrew M. Bradbury · 2010 · Current Protocols in Neuroscience
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    Jiangchao Xiang, Jie Su, Qiaoshuai Lan, Wenwen Zhao, Yu Zhou, Youwei Xu, Jun Niu, Shuai Xia, Qilian Qi, Sachdev S. Sidhu et al. · 2022 · Communications Biology
40. Deep mining of antibody phage-display selections using Oxford Nanopore Technologies and Dual Unique Molecular Identifiers
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41. Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope
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42. Prediction of Antibody Epitopes
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43. FN3-based monobodies selective for the receptor binding domain of the SARS-CoV-2 spike protein
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    Debbie C. P. Lee, Rahul Raman, Nahdiyah Abdul Ghafar, Yadunanda Budigi · 2021 · Antiviral Research
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    Hye Lim Choi, Ha Rim Yang, Ha Gyeong Shin, Kyusang Hwang, Ji Woong Kim, Ji‐Hyun Lee, Taehoon Ryu, Yushin Jung, Sukmook Lee · 2023 · International Journal of Molecular Sciences
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    Murat Karadag, Merve Arslan, Nazlı Eda Kaleli, Sibel Kalyoncu · 2019 · Advances in protein chemistry and structural biology
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    Sepideh Ghani, Mojgan Bandehpour, Fatemeh Yarian, Kaveh Baghaei, Bahram Kazemi · 2023 · Applied Biochemistry and Biotechnology
49. A novel β-loop scaffold of phage-displayed peptides for highly specific affinities
    Toshiki Sawada, Kojiro Ishiguro, Tsuyoshi Takahashi, Hisakazu Mihara · 2011 · Molecular BioSystems
50. Structural mechanism of Fab domain dissociation as a measure of interface stability
    Nancy D. Pomarici, Franz Waibl, Patrick K. Quoika, Alexander Bujotzek, Guy J. Georges, Monica L. Fernández‐Quintero, Klaus Roman Liedl · 2023 · Journal of Computer-Aided Molecular Design
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    Rita Ribeiro, João Nuno Moreira, João Gonçalves · 2024 · Scientific Reports
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    Lucas Joel Gutiérrez, Sebastián A. Andújar, Ricardo Daniel Enriz, Héctor A. Baldoni · 2013 · Journal of Biomolecular Structure and Dynamics
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    Zirui Zhu, Katherine S. Olson, Thomas J. Magliery · 2024 · Antibodies
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    Orlee Marini‐Rapoport, Moumita Bhowmik, Tarun Keswani, Sarita U. Patil · 2025 · Immunological Reviews
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    Ivan Poddiakov, Dmitriy Umerenkov, Irina Shulcheva, Victoria Golovina, Vasilina Borisova, Irina Pozdnyakova-Filatova, Evgeniy Loktyushov, Galina Zubkova, A. Savchenko, A. B. Ulitin et al. · 2025 · Scientific Reports
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    Linda Schwaigerlehner, Maria Pechlaner, Patrick Mayrhofer, Chris Oostenbrink, Renate Kunert · 2018 · Protein Engineering Design and Selection
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    Fortunato Ferrara, Chang‐Yub Kim, Leslie A. Naranjo, Andrew M. Bradbury · 2014 · mAbs
58. Antibody Polyreactivity: A Challenger of Immune Paradigms
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59. Specific RNA-Binding Antibodies with a Four-Amino-Acid Code
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    Raquel Gutiérrez‐Climente, Giang Ngo, Margaux Clavié, Jérémie Gouyon, Yoann Ladner, Pascal Etienne, Pascal Dumy, Catherine Perrin, Ahmad Mehdi, Pierre Martineau et al. · 2022 · Materials Today Chemistry
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    Temitope I. David, Nikolay Borisovich Pestov, Tatyana V. Korneenko, Nickolai A. Barlev · 2023 · Biochemistry (Moscow)
62. Predictive Models and Impact of Interfacial Contacts and Amino Acids on Protein–Protein Binding Affinity
    C. Yi, M. L. Taylor, J. Ziebarth, Yong-Mei Wang · 2023 · bioRxiv
63. The Immunoglobulin Genes of Bats
    J.E. Butler, Nancy Wertz, Michelle L. Baker · 2014 · Apple Academic Press eBooks
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    Colton J. Bracken, Shion An Lim, Paige E. Solomon, Nicholas J. Rettko, Duy Nguyen, Beth Shoshana Zha, Kaitlin Schaefer, James R. Byrnes, Jie Zhou, Irene Lui et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
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    Jérémie Gouyon, Margaux Clavié, Raquel Gutiérrez‐Climente, Giang Ngo, Pascal Dumy, Pascal Etienne, Pierre Martineau, Martine Pugnière, Ahmad Mehdi, Gilles Subra et al. · 2023 · Electrophoresis
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    Tsung-Yi Lin, Jonathan R. Lai · 2017 · Bioorganic & Medicinal Chemistry
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    Maria T Vakhitova, Mikhail Yu. Myshkin, Dmitriy B. Staroverov, Irina A. Shagina, Mark Izraelson, Nadezhda Tverdova, Olga V. Britanova, Ekaterina M. Merzlyak · 2023 · Cells
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    Neal Hopkins · 2009 · Springer eBooks
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    Mark Hubbard, Peter Thorkildson, William H. Welch, Thomas R. Kozel · 2013 · Molecular Immunology
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    Yuwei Zhou, Haoxiang Tang, Changchun Wu, Zixuan Zhang, Jinyi Wei, Rong Gong, Samarappuli Mudiyanselage Savini Gunarathne, Changcheng Xiang, Jian Hua Huang · 2025 · Journal of Pharmaceutical Analysis
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    Yuan Yao, Celestine Hong, Carter J Teal, Noor E. Bahsoun, Sophia P. Lu, Ian Fernandes, Gordon M. Keller, M. Shoichet · 2025 · Acta Biomaterialia
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    Helena Persson, Jonas Persson, Lena Danielsson, Mats Ohlin · 2009 · Journal of Immunological Methods
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    Ningyu Zhu, Philip M. Smallwood, Amir Rattner, Tao-Hsin Chang, John Williams, Yanshu Wang, Jeremy Nathans · 2024 · Journal of Biological Chemistry
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    Yuan Lin · 2011 · AFRICAN JOURNAL OF BIOTECHNOLOGY
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    Diane A. Blake, Bhupal Ban, X. Li, Robert C. Blake, Grace A. Jairo, Yue Ming Sun · 2014 · Springer eBooks
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    Edward P. Harvey, Jung-Eun Shin, Meredith A. Skiba, Genevieve R. Nemeth, Joseph D. Hurley, Alon Wellner, Ada Y. Shaw, Victor G. Miranda, Joseph Min, Chang C. Liu et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
96. Antibodies
    Moncef Zouali · 2016 · Wiley eBooks
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    Lucas Joel Gutiérrez, Rodrigo D. Tosso, M. Natalia C. Zarycz, Ricardo Daniel Enriz, Héctor A. Baldoni · 2022 · Molecular Simulation
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    Anil Kumar Nagraj, Riya Patel, Akshata Gavade, Roylan Pais, Pratibha Verma, Jaspal Patil · 2025 · In Silico Pharmacology
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    Alec A. Desai, Matthew D. Smith, Jennifer M. Zupancic, Emily K. Makowski, Yulei Zhang, Julia E. Gerson, Shannon J. Moore, Alexandra B. Sutter, Sean P. Ferris, Magdalena I. Ivanova et al. · 2025 · Frontiers in Immunology
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