Sidhu, Sachdev S.

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

Hart, T., Chandrashekhar, M., Aregger, M., Steinhart, Z., Brown, K. R., MacLeod, G., Mis, M., Zimmermann, M., Fradet-Turcotte, A., Sun, S., et al. (2015) · Cell

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

Cited by 1,571

A Specificity Map for the PDZ Domain Family

Tonikian, R., Zhang, Y., Sazinsky, S. L., Currell, B., Yeh, J.-H., Reva, B., Held, H. A., Appleton, B. A., Evangelista, M., Wu, Y., et al. (2008) · PLoS Biology

Protein Structure and DynamicsChemical Synthesis and Analysis

Cited by 476

Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2

Case, J. B., Rothlauf, P. W., Chen, R. E., Liu, Z., Zhao, H., Kim, A. S., Bloyet, L.-M., Zeng, Q., Tahan, S., Droit, L., et al. (2020) · Cell Host & Microbe

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 410

The Intrinsic Contributions of Tyrosine, Serine, Glycine and Arginine to the Affinity and Specificity of Antibodies

Birtalan, S., Zhang, Y., Fellouse, F. A., Shao, L., Schaefer, G., & Sidhu, S. S. (2008) · Journal of Molecular Biology

Monoclonal and Polyclonal Antibodies ResearchChemical Synthesis and Analysis

Cited by 244

Comprehensive analysis of the factors contributing to the stability and solubility of autonomous human VH domains

Barthelemy, P. A., Raab, H., Appleton, B. A., Bond, C. J., Wu, P., Wiesmann, C., & Sidhu, S. S. (2008) · Journal of Biological Chemistry

Monoclonal and Polyclonal Antibodies ResearchProtein purification and stability

Cited by 179

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes

Zhang, W., Wu, K.-P., Sartori, M. A., Kamadurai, H. B., Ordureau, A., Jiang, C., Mercredi, P. Y., Murchie, R., Hu, J., Persaud, A., et al. (2016) · Molecular Cell

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 168

Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes

Ivarsson, Y., Arnold, R., McLaughlin, M., Nim, S., Joshi, R., Ray, D., Liu, B., Teyra, J., Pawson, T., Moffat, J., et al. (2014) · Proceedings of the National Academy of Sciences

Chemical Synthesis and AnalysisAdvanced Proteomics Techniques and Applications

Cited by 135

Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b

Hu, S., Liu, S., Bian, Y., Poddar, M., Singh, S., Cao, C., McGaughey, J., Bell, A., Blazer, L. L., Adams, J. J., et al. (2022) · Cell Reports Medicine

Liver physiology and pathologyWnt/β-catenin signaling in development and cancer

Cited by 118

A Potent d -Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo

Uppalapati, M., Lee, D. J., Mandal, K., Li, H., Miranda, L. P., Lowitz, J., Kenney, J., Adams, J. J., Ault-Riché, D., Kent, S. B. H., et al. (2016) · ACS Chemical Biology

Chemical Synthesis and AnalysisMonoclonal and Polyclonal Antibodies Research

Cited by 113

A novel immunotherapy targeting MMP-14 limits hypoxia, immune suppression and metastasis in triple-negative breast cancer models

Ling, B., Watt, K., Banerjee, S., Newsted, D., Truesdell, P., Adams, J., Sidhu, S. S., & Craig, A. W. B. (2017) · Oncotarget

Protease and Inhibitor MechanismsMonoclonal and Polyclonal Antibodies Research

Cited by 92

Animal‐friendly affinity reagents: replacing the needless in the haystack

Gray, A. C., Sidhu, S. S., Chandrasekera, P. C., Hendriksen, C. F. M., & Borrebaeck, C. A. K. (2016) · Trends in Biotechnology

Animal testing and alternativesMonoclonal and Polyclonal Antibodies Research

Cited by 55

Innate Control of Tissue-Reparative Human Regulatory T Cells

Lam, A. J., MacDonald, K. N., Pesenacker, A. M., Juvet, S. C., Morishita, K. A., Bressler, B., iGenoMed Consortium, Pan, J. G., Sidhu, S. S., Rioux, J. D., et al. (2019) · The Journal of Immunology

IL-33, ST2, and ILC PathwaysT-cell and B-cell Immunology

Cited by 47

Evolving specificity from variability for protein interaction domains

Kaneko, T., Sidhu, S. S., & Li, S. S. C. (2011) · Trends in Biochemical Sciences

Protein Structure and DynamicsChemical Synthesis and Analysis

Cited by 45