Adhesions and pain in women with first diagnosis of endometriosis: Results from a cross-sectional study
Abstract
Objective To analyze the relationship between pain and presence, site, and type of adhesions in women with endometriosis. Methods This was a multicenter, observational cross-sectional study. Eligible for the study were women with endometriosis and pelvic pain, consecutively observed during the study period at the collaborating centers. A total of 574 women entered the study. Results Adhesions were observed in 81.9% of cases (470 women). The frequency was lower in women with endometriosis at stage I-II (65%) and higher in women with stage III-IV (88%); this difference was statistically significant (p Conclusions The results of this study suggest that there is no overall association between the presence of adhesions and the degree of pain in women with endometriosis. The data suggests that there may be an association between adhesions and pain in women with ovarian and Type I-II endometriosis. However, these associations were no longer significant after correction for multiple comparisons. Further research is indicated to test these associations.
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The contribution of adhesions to pain in endometriosis remains poorly understood.
“The role of adhesions in pain and endometriosis is poorly understood”
From Chronic pelvic pain and endometriosis: translational evidence of the relationship and implications (2011) · cites this paper as Parazzini et al., 2006
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Vercellini, P., Fedele, L., Aimi, G., Pietropaolo, G., Consonni, D., & Crosignani, P. G. (2007) · Human Reproduction · doi:10.1093/humrep/del339 · Cited by 547 · see citing works
Chronic pelvic pain and endometriosis: translational evidence of the relationship and implications
Stratton, P., & Berkley, K. J. (2011) · Human Reproduction Update · doi:10.1093/humupd/dmq050 · Cited by 442 · see citing works
Endometriosis in young women: the experience of GISE
Vicino, M., Parazzini, F., Cipriani, S., & Frontino, G. (2010) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2009.12.002 · Cited by 42 · see citing works
Self-citation
- Authors
- Parazzini, F., Mais, V., & Cipriani, S.
- Venue
- Journal of Minimally Invasive Gynecology
- Publisher
- Elsevier BV
- Published
- 2006-01
- Volume
- 13
- Issue
- 1
- Pages
- 49-54
- ISSN
- 1553-4650 (ISSN-L)
- OpenAlex
- W2402497023
- Cited by
- 28
- References
- 0
- Citations by year
- 2026: 2 · 2025: 2 · 2023: 1 · 2021: 2 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 2 · 2014: 2
- FWCI
- 1.76
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Minimally Invasive Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Florence Research (University of Florence) (submittedVersion)
- UNICA IRIS Institutional Research Information System (University of Cagliari) (submittedVersion)
- IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
- UnissResearch (Università degli Studi di Sassari) (submittedVersion)
- Institutional Research Information System University of Turin (University of Turin) (submittedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Surgery › Intestinal and Peritoneal Adhesions
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Keywords
- endometriosis, pelvic adhesions, pelvic pain, endometrioma, peritoneal endometriosis, endometriosis stage, pain intensity
- MeSH terms
- Tissue Adhesions, Adolescent, Adult, Cross-Sectional Studies, Endometriosis, Female, Humans, Middle Aged, Ovarian Diseases, Pain Measurement, Peritoneal Diseases, Surveys and Questionnaires, Chi-Square Distribution, Pelvic Pain, Statistics, Nonparametric
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