Endometriosis in young women: the experience of GISE
Abstract
Study objective To analyze the clinical manifestations of endometriosis in adolescents. Design prospective clinical study. Setting University and General hospitals. Participants A total of 38 females aged Results The mean age at diagnosis was 18.6 years, except in 3 cases (7.9%) in which it was made at Conclusions The main clinical finding emerging from this analysis suggests that pelvic pain is the main symptom. In our series pain was present in all cases and an ovarian endometrioma was present in three cases. With regard to the stage and site of the disease, the frequency of minimal-mild endometriosis was lower than in adult cases observed in the experience of GISE.
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In adolescents, cyclical pelvic pain is suggestive of the presence of endometriosis.
“In adolescents, clinicians should take a careful history and consider the following symptoms as suggestive of the presence of endometriosis: chronic or acyclical pelvic pain, particularly combined with nausea, dysmenorrhoea, dyschezia, dysuria, dyspareunia;cyclical pelvic pain (Greene et al., 2009; Treloar et al., 2010; Vicino et al., 2010; Yang et al., 2012; DiVasta et al., 2018).”
From ESHRE guideline: endometriosis (2022) · cites this paper as Vicino et al., 2010
In adolescents, chronic or acyclical pelvic pain, particularly combined with nausea, dysmenorrhoea, dyschezia, dysuria, dyspareunia, is suggestive of the presence of endometriosis.
“In adolescents, clinicians should take a careful history and consider the following symptoms as suggestive of the presence of endometriosis: chronic or acyclical pelvic pain, particularly combined with nausea, dysmenorrhoea, dyschezia, dysuria, dyspareunia;cyclical pelvic pain (Greene et al., 2009; Treloar et al., 2010; Vicino et al., 2010; Yang et al., 2012; DiVasta et al., 2018).”
From ESHRE guideline: endometriosis (2022) · cites this paper as Vicino et al., 2010
Cites
Revised American Society for Reproductive Medicine classification of endometriosis: 1996
American Society for Reproductive Medicine (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)81391-x · Cited by 3,018 · see citing works
Laufer, M. R., Goitein, L., Bush, M., Cramer, D. W., & Emans, S. J. (1997) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/s1083-3188(97)70085-8 · Cited by 305 · see citing works
Endometriosis in an Adolescent Population: The Emory Experience
Reese, K. A., Reddy, S., & Rock, J. A. (1996) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/s1083-3188(96)70021-9 · Cited by 160 · see citing works
dell'endometriosi*, G. I. P. L. S. (1994) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a138650 · Cited by 148 · see citing works
Nezhat, C. H. (2020) · Springer eBooks · doi:10.1007/978-3-030-52984-0 · Cited by 145 · see citing works
GOLDSTEIN, D. P., de Cholnoky, C., & Emans, S. J. (1980) · Journal of Adolescent Health Care · doi:10.1016/s0197-0070(80)80007-6 · Cited by 140 · see citing works
Clinical characteristics of adolescent endometriosis
DAVIS, G., THILLET, E., & LINDEMANN, J. (1993) · Journal of Adolescent Health · doi:10.1016/s1054-139x(08)80008-0 · Cited by 116 · see citing works
Laparoscopy in the diagnosis of chronic pelvic pain in adolescent women.
Vercellini, P., Fedele, L., Arcaini, L., Bianchi, S., Rognoni, M. T., & Candiani, G. B. (1989) · PubMed · Cited by 105 · see citing works
Laparoscopic treatment of endometriosis in teenagers
Stavroulis, A., Sarıdoğan, E., Creighton, S. M., & Cutner, A. S. (2005) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2005.08.024 · Cited by 62 · see citing works
Endometriosis in adolescents. Incidence, diagnosis and treatment.
Propst, A. M., & Laufer, M. R. (1999) · PubMed · Cited by 55 · see citing works
Laparoscopic evaluation and management of chronic pelvic pain during adolescence.
Kontoravdis, A., Hassan, E., Hassiakos, D., Botsis, D. S., Kontoravdis, N., & Creatsas, G. K. (1999) · PubMed · Cited by 55 · see citing works
Endometriosis diagnosed by laparoscopy in adolescent girls
Emmert, C., Romann, D., & Riedel, H. ‐. (1998) · Archives of Gynecology and Obstetrics · doi:10.1007/s004040050205 · Cited by 34 · see citing works
Endometriosis in an Adolescent Population: the Severance Hospital in Korean Experience
Bai, S. W., Cho, H.-J., Kim, J. Y., Jeong, K. A., Kim, S. K., Cho, D. J., Song, C. H., & Park, K. H. (2002) · Yonsei Medical Journal · doi:10.3349/ymj.2002.43.1.48 · Cited by 33 · see citing works
Endometriosis in adolescence: a long-term follow-up fecundability assessment.
Ventolini, G., Horowitz, G. M., & Long, R. (2005) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-3-14 · Cited by 32 · see citing works
(2006) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2005.10.002 · Cited by 28 · see citing works
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ESHRE guideline: endometriosis
Becker, C. M., Bokor, A., Heikinheimo, O., Horne, A., Jansen, F., Kiesel, L., King, K., Kvaskoff, M., Nap, A., Petersen, K., et al. (2022) · Human Reproduction Open · doi:10.1093/hropen/hoac009 · Cited by 1,712 · see citing works
“…as suggestive of the presence of endometriosis: chronic or acyclical pelvic pain, particularly combined with nausea, dysmenorrhoea, dyschezia, dysuria, dyspareunia; cyclical pelvic pain (Greene et al. , 2009; Treloar et al. , 2010; Vicino et al. , 2010; Yang et al. , 2012; DiVasta et al. , 2018).”
Janssen, E. B., Rijkers, A. C. M., Hoppenbrouwers, K., Meuleman, C., & D'Hooghe, T. M. (2013) · Human Reproduction Update · doi:10.1093/humupd/dmt016 · Cited by 318 · see citing works
Primary Dysmenorrhea in Adolescents: Prevalence, Impact and Recent Knowledge.
Sanctis, V. D., Soliman, A. T., Bernasconi, S., Bianchin, L., Bona, G., Bozzola, M., Buzi, F., Sanctis, C. D., Tonini, G., Rigon, F., et al. (2015) · PubMed · Cited by 232 · see citing works
Peter, A. W., Adamson, G. D., Al‐Jefout, M., Becker, C. M., D’Hooghe, T. M., Dunselman, G. A. J., Fazleabas, A. T., Giudice, L. C., Horne, A. W., Hull, M. L., et al. (2016) · Reproductive Sciences · doi:10.1177/1933719116654991 · Cited by 188 · see citing works
Brosens, I., Gordts, S., & Benagiano, G. (2013) · Human Reproduction · doi:10.1093/humrep/det243 · Cited by 184 · see citing works
High rate of endometriosis recurrence in young women
Tandoi, I., Somigliana, E., Riparini, J., Ronzoni, S., Vigano’, P., & Candiani, M. (2011) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2011.06.012 · Cited by 112 · see citing works
The Prevalence of Endometriosis in Adolescents with Pelvic Pain: A Systematic Review
Hirsch, M., Dhillon‐Smith, R. K., Cutner, A. S., Yap, M., & Creighton, S. M. (2020) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2020.07.011 · Cited by 104 · see citing works
Yeung, P., Sinervo, K., Winer, W., & Albee, R. B. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.02.037 · Cited by 84 · see citing works
Origins and Progression of Adolescent Endometriosis
Brosens, I. A., Gargett, C. E., Guo, S., Puttemans, P., Gordts, S., Brosens, J. J., & Benagiano, G. (2016) · Reproductive Sciences · doi:10.1177/1933719116637919 · Cited by 73 · see citing works
Sarıdoğan, E. (2017) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2016.05.019 · Cited by 62 · see citing works
Progress in the diagnosis and management of adolescent endometriosis: an opinion
Benagiano, G., Guo, S., Puttemans, P., Gordts, S., & Brosens, I. A. (2017) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2017.09.015 · Cited by 61 · see citing works
Adolescent endometriosis: prevalence increases with age on magnetic resonance imaging scan
Millischer, A., Santulli, P., Costa, S. D., Bordonné, C., Cazaubon, E., Marcellin, L., & Chapron, C. (2022) · Fertility and Sterility · doi:10.1016/j.fertnstert.2022.12.039 · Cited by 58 · see citing works
Is primary dysmenorrhea a precursor of future endometriosis development?
Clemenza, S., Vannuccini, S., Capezzuoli, T., Meleca, C. I., Pampaloni, F., & Petraglia, F. (2021) · Gynecological Endocrinology · doi:10.1080/09513590.2021.1878134 · Cited by 50 · see citing works
Advanced Stage Endometriosis in Adolescents and Young Women
Smorgick, N., As‐Sanie, S., Marsh, C. A., Smith, Y. R., & Quint, E. H. (2014) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2013.12.010 · Cited by 46 · see citing works
Scientific Investigation of Endometriosis among Adolescents
Shah, D. K., & Missmer, S. A. (2011) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2011.07.008 · Cited by 44 · see citing works
Ragab, A., Shams, M., & Badawy, A. (2015) · International Journal of Health Sciences · doi:10.12816/0024694 · Cited by 41 · see citing works
Recurrence of Ovarian Endometrioma in Adolescents after Conservative, Laparoscopic Cyst Enucleation
Lee, S. Y., Kim, M., Seong, S. J., Bae, J. W., & Cho, Y. J. (2015) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2015.11.001 · Cited by 38 · see citing works
Noninvasive Diagnosis of Endometriosis in Adolescents and Young Female Adults: A Systematic Review
Oliveira, I. T., Pinto, P. V., & Bernardes, J. (2024) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2024.07.005 · Cited by 34 · see citing works
Endometriosis in Adolescents: A Systematic Review
Yeung, P., Gupta, S. M., & Gieg, S. (2017) · Journal of Endometriosis and Pelvic Pain Disorders · doi:10.5301/je.5000264 · Cited by 31 · see citing works
Endometriosis is an important cause of pelvic pain in adolescence
Andres, M. P., Podgaec, S., Carreiro, K. B., & Baracat, E. C. (2014) · Revista da Associação Médica Brasileira · doi:10.1590/1806-9282.60.06.015 · Cited by 29 · see citing works
Canis, M. J., Bourdel, N., Houlle, C., Grémeau, A.-S., Botchorishvili, R., & Matsuzaki, S. (2017) · Journal of Gynecology Obstetrics and Human Reproduction · doi:10.1016/j.jogoh.2016.12.008 · Cited by 27 · see citing works
A focus on the distinctions and current evidence of endometriosis in adolescents
Sanctis, V. D., Matalliotakis, M., Soliman, A. T., Elsefdy, H., Maio, S. D., & Fiscina, B. (2018) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2018.01.023 · Cited by 26 · see citing works
Pain Levels of Women Diagnosed with Endometriosis: Is There a Difference in Younger Women?
Wüest, A., Jm, L., Dingeldein, I., Siegenthaler, F., Vaineau, C., Wilhelm, I., Mueller, M. D., & Imboden, S. (2022) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2022.10.011 · Cited by 24 · see citing works
Clinical Characteristics of Adolescent Endometrioma
Lee, D., Kim, H. J., Yoon, B.-K., & Choi, D. (2013) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2012.11.011 · Cited by 23 · see citing works
Sarıdoğan, E. (2015) · Women s Health · doi:10.2217/whe.15.58 · Cited by 20 · see citing works
Al‐Jefout, M., Alnawaiseh, N. A., Yaghi, S., & Alqaisi, A. (2017) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/j.jogc.2017.06.042 · Cited by 20 · see citing works
Surgical Considerations in the Management of Adolescent Endometriosis—An Expert Commentary
Tyson, N. A., Shim, J. Y., Lee, T., King, C. R., Einarsson, J. I., Hornstein, M. D., & Laufer, M. R. (2024) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2024.01.021 · Cited by 17 · see citing works
Seo, J.-W., Lee, D.-Y., Yoon, B.-K., & Choi, D. (2017) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2016.10.004 · Cited by 17 · see citing works
Bailey, A. P., Hill, A. S., Beste, M. T., Cook, C. D., Sarda, V., Laufer, M. R., Isaacson, K., Griffith, L. G., & Missmer, S. A. (2020) · American Journal of Reproductive Immunology · doi:10.1111/aji.13347 · Cited by 13 · see citing works
Endometriosis in adolescent and young women
Benagiano, G., Bianchi, P., & Guo, S. (2021) · Minerva Obstetrics and Gynecology · doi:10.23736/s2724-606x.21.04764-x · Cited by 10 · see citing works
Endometrioma in Adolescents and Future Reproductive Health
Brosens, I. A., & Benagiano, G. (2017) · Journal of Endometriosis and Pelvic Pain Disorders · doi:10.5301/je.5000267 · Cited by 5 · see citing works
Prevalence, Surgical, and Medical Management of Patients with Endometriosis amongst Indian Women
Rozati, R., Tabasum, W., Ahmed, M. S., Khan, A. A., Ahmed, T. N., Nayela, S., & Azimi, S. S. (2023) · European Journal of Medical and Health Sciences · doi:10.24018/ejmed.2023.5.6.1985 · Cited by 4 · see citing works
Endometriosis surgery in young women: a narrative review
Sarıdoğan, E., & Saridogan, E. (2021) · Gynecology and Pelvic Medicine · doi:10.21037/gpm-20-57 · Cited by 3 · see citing works
Laparoscopic Surgery in Adolescent Endometriosis
Soriano, D., & Bar-Shavit, Y. (2020) · Springer eBooks · doi:10.1007/978-3-030-52984-0_36 · Cited by 3 · see citing works
Lewin, J., Learner, H. I., Vashisht, A., Vincent, K., Sarıdoğan, E., Becker, C. M., & Hirsch, M. (2026) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2026.01.006 · Cited by 1 · see citing works
Kaplanoğlu, M., Çetin, Ç., Kaplanoğlu, D. K., & ÇETİN, M. T. (2020) · Türk Üreme Tıbbı ve Cerrahisi Dergisi · doi:10.24074/tjrms.2019-72881 · Cited by 1 · see citing works
The Clinical Diagnosis of Pelvic Endometriosis in Adolescents
Bianchi, P. I. (2017) · MOJ Women s Health · doi:10.15406/mojwh.2017.04.00089 · Cited by 1 · see citing works
Pain Levels of Women Diagnosed with Endometriosis: Is There a Difference in Younger Women?
Wüest, A., Jm, L., Dingeldein, I., Siegenthaler, F., Vaineau, C., Wilhelm, I., Mueller, M., & Imboden, S. (2023) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2023.01.176 · Cited by 1 · see citing works
Szubert, M., Wierzbowski, T., Suzin, J., & Kowalczyk-Amico, K. (2013) · Menopause Review/Przegląd Menopauzalny · doi:10.5114/pm.2013.36591
Imaging Emergency Pelvic Diseases in Girls
Verpillat, P., Chateil, J., Durand, C., & Avni, F. E. (2017) · Springer eBooks · doi:10.1007/978-3-319-63700-6_24
Stringel, G. (2020) · Springer eBooks · doi:10.1007/978-3-030-52984-0_43
Hartati, F., Ocviyanti, D., Effendi, Y., Amin, R., Permadi, W., Saleh, M. I., Hafy, Z., & Stevanny, B. (2026) · Journal of South Asian Federation of Obstetrics and Gynaecology · doi:10.5005/jp-journals-10006-2871
- Authors
- Vicino, M., Parazzini, F., Cipriani, S., & Frontino, G.
- Corresponding author
- Parazzini, Fabio
- Venue
- Journal of Pediatric and Adolescent Gynecology
- Publisher
- Elsevier BV
- Published
- 2010-08
- Volume
- 23
- Issue
- 4
- Pages
- 223-225
- ISSN
- 0932-8610 (ISSN-L)
- 1083-3188
- OpenAlex
- W1980112878
- Cited by
- 42
- References
- 15
- Citations by year
- 2026: 2 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 3 · 2020: 5 · 2018: 1 · 2017: 7 · 2016: 4 · 2015: 4 · 2014: 2 · 2013: 4
- FWCI
- 2.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Pediatric and Adolescent Gynecology (publishedVersion)
- PubMed (publishedVersion)
- UNICA IRIS Institutional Research Information System (University of Cagliari) (submittedVersion)
- CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro) (submittedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ectopic Pregnancy Diagnosis and Management
- Keywords
- endometriosis, adolescent endometriosis, young women, pelvic pain, endometrioma, endometriosis staging, age at diagnosis, clinical features
- MeSH terms
- Adolescent, Endometriosis, Female, Humans, Laparoscopy, Gynecologic Surgical Procedures, Pelvic Pain, Young Adult
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