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Validation and Implementation of a Custom Next-Generation Sequencing Clinical Assay for Hematologic Malignancies

Kluk, Michael J., Lindsley, R. Coleman, Aster, Jon C., Lindeman, Neal I., Szeto, David, Hall, Dimity, Kuo, Frank C.·2016·The Journal of Molecular Diagnostics
DOI 10.1016/j.jmoldx.2016.02.003
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Research works printed but not linked: 26

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  2. Lindsley, 2013, The biology and clinical impact of genetic lesions in myeloid malignancies, Blood, 122, 3741, 10.1182/blood-2013-06-460295 · DOI
  3. Lundberg, 2014, Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms, Blood, 123, 2220, 10.1182/blood-2013-11-537167 · DOI
  4. Matynia, 2015, Molecular genetic biomarkers in myeloid malignancies, Arch Pathol Lab Med, 139, 594, 10.5858/arpa.2014-0096-RA · DOI
  5. Meyer, 2014, Translational implications of somatic genomics in acute myeloid leukaemia, Lancet Oncol, 15, e382, 10.1016/S1470-2045(14)70008-7 · DOI
  6. Zoi, 2015, Molecular pathogenesis of atypical CML, CMML and MDS/MPN-unclassifiable, Int J Hematol, 101, 229, 10.1007/s12185-014-1670-3 · DOI
  7. Lindsley, 2015, Acute myeloid leukemia ontogeny is defined by distinct somatic mutations, Blood, 125, 1367, 10.1182/blood-2014-11-610543 · DOI · Paper page
  8. Zhang, 2015, The molecular basis and clinical significance of genetic mutations identified in myelodysplastic syndromes, Leuk Res, 39, 6, 10.1016/j.leukres.2014.10.006 · DOI
  9. Kohlmann, 2014, Perspective on how to approach molecular diagnostics in acute myeloid leukemia and myelodysplastic syndromes in the era of next-generation sequencing, Leuk Lymphoma, 55, 1725, 10.3109/10428194.2013.856427 · DOI
  10. Duncavage, 2012, Targeted next generation sequencing of clinically significant gene mutations and translocations in leukemia, Mod Pathol, 25, 795, 10.1038/modpathol.2012.29 · DOI
  11. Cheng, 2014, Detection of mutations in myeloid malignancies through paired-sample analysis of microdroplet-PCR deep sequencing data, J Mol Diagn, 16, 504, 10.1016/j.jmoldx.2014.05.006 · DOI
  12. Luthra, 2014, Next-generation sequencing-based multigene mutational screening for acute myeloid leukemia using MiSeq: applicability for diagnostics and disease monitoring, Haematologica, 99, 465, 10.3324/haematol.2013.093765 · DOI
  13. Koskela, 2012, Somatic STAT3 mutations in large granular lymphocytic leukemia, N Engl J Med, 366, 1905, 10.1056/NEJMoa1114885 · DOI
  14. Treon, 2012, MYD88 L265P somatic mutation in Waldenström's macroglobulinemia, N Engl J Med, 367, 826, 10.1056/NEJMoa1200710 · DOI
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  16. Rossi, 2012, The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development, J Exp Med, 209, 1537, 10.1084/jem.20120904 · DOI
  17. Kon, 2013, Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms, Nat Genet, 45, 1232, 10.1038/ng.2731 · DOI
  18. Bonnet, 1997, Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell, Nat Med, 3, 730, 10.1038/nm0797-730 · DOI · Paper page
  19. Gambacorti-Passerini, 2015, Recurrent ETNK1 mutations in atypical chronic myeloid leukemia, Blood, 125, 499, 10.1182/blood-2014-06-579466 · DOI
  20. Thol, 2014, Mutations in the cohesin complex in acute myeloid leukemia: clinical and prognostic implications, Blood, 123, 914, 10.1182/blood-2013-07-518746 · DOI
  21. Grasso, 2015, Assessing copy number alterations in targeted, amplicon-based next-generation sequencing data, J Mol Diagn, 17, 53, 10.1016/j.jmoldx.2014.09.008 · DOI
  22. Hoogstraat, 2015, Simultaneous detection of clinically relevant mutations and amplifications for routine cancer pathology, J Mol Diagn, 17, 10, 10.1016/j.jmoldx.2014.09.004 · DOI
  23. Kampa-Schittenhelm, 2013, Quizartinib (AC220) is a potent second generation class III tyrosine kinase inhibitor that displays a distinct inhibition profile against mutant-FLT3, -PDGFRA and -KIT isoforms, Mol Cancer, 12, 19, 10.1186/1476-4598-12-19 · DOI
  24. Wang, 2013, Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation, Science, 340, 622, 10.1126/science.1234769 · DOI · Paper page
  25. Hatzimichael, 2013, Gene mutations and molecularly targeted therapies in acute myeloid leukemia, Am J Blood Res, 3, 29
  26. Kuo, 2015, Next-generation sequencing-based panel testing for myeloid neoplasms, Curr Hematol Malig Rep, 10, 104, 10.1007/s11899-015-0256-3 · DOI

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Metadata

Authors
Kluk, M. J., Lindsley, R. C., Aster, J. C., Lindeman, N. I., Szeto, D., Hall, D., & Kuo, F. C.
Venue
The Journal of Molecular Diagnostics
Publisher
Elsevier BV
Published
2016-07
Volume
18
Issue
4
Pages
507-515
ISSN
1525-1578
DOI
10.1016/j.jmoldx.2016.02.003
Cited by
178
References
6
Language
en
Licence

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