Nano Biosensors: Properties, applications and electrochemical techniques

Abstract

A sensor is a tool used to directly measure the test compound (analyte) in a sample. Ideally, such a device is capable of continuous and reversible response and should not damage the sample. Nanosensor refers to a system in which at least one of the nanostructures is used to detect gases, chemicals, biological agents, electric fields, light, heat, etc. in its construction. The use of nanomaterials significantly increases the sensitivity of the system. In biosensors, the part of the system used to attach to the analyte and specifically detect it is a biological element (such as a DNA strand, antibody, enzyme, whole cell). The “Nano Biosensors” series reviews various types of biosensors and biochips (including an array of biosensors), emphasizing the role of nanostructures, developed for medical and biological applications. Nano Biosensors Electrochemical sensors are sensors that use the biological element as a diagnostic component and the electrode as a transducer. The use of nanostructures in these systems is usually done to fill the gap between the converter and the bioreceptor, which is at the nanoscale. Given the nature of the biomaterial detection process, electrochemical biosensors are divided into catalytic and propulsion. Common electrochemical techniques common in sensors include potentiometric, chronometry, voltammetry, impedance measurement, and field effect transistor (FET). Simultaneous use of the advantages of nanostructures and electrochemical techniques has led to the emergence of sensors with high sensitivity and decomposition power. The use of nanostructures in these sensors is usually done to fill the gap between the converter and the bioreceptor, which is at the nanoscale. Various types of nanostructures including nanoparticles, nanotubes and nanowires, nanopores, self-adhesive monolayers and nanocomposites can be used to improve the performance and efficiency of sensors in their structure. Simultaneous use of the advantages of nanostructures and electrochemical techniques has led to the emergence of sensors with high sensitivity and decomposition power.