Use of A clean delivery kit and factors associated with cord infection and puerperal sepsis in mwanza, Tanzania
Abstract
Our objective was to determine the effectiveness of an intervention that incorporated education about the “six cleans” with the use of a clean delivery kit in preventing cord infection and puerperal sepsis. A stepped‐wedge, cross‐sectional study was conducted in 10 surveillance sites across two rural districts of Mwanza Region, Tanzania. A total of 3262 pregnant women between the ages of 17 and 45 years were enrolled in the study. Village health workers administered questionnaires to each mother at 5 days postpartum and inspected the infants'umbilical cord stumps for signs of infection. Newborns whose mothers used the delivery kit were 13.1 times less likely to develop cord infection than infants whose mothers did not use the kit. Furthermore, women who used the kit for delivery were 3.2 times less likely to develop puerperal sepsis than women who did not use the kit. Women who bathed before delivery were 2.6 times less likely to develop puerperal sepsis than women who did not bathe, and their infants were 3.9 times less likely to develop cord infection. Single‐use delivery kits, when combined with education about clean delivery, can have a positive impact on the health of women and their newborns by significantly decreasing the likelihood of developing puerperal sepsis or cord infection.
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The stepped-wedge design in Winani et al. 2007 ensured that all clusters eventually received the intervention while maintaining randomization.
“The stepped-wedge design ensured that all clusters eventually received the intervention while maintaining randomization.”
From Applications and implementation considerations for stepped-wedge designs in sub-Saharan Africa: a systematic review (2026) · cites this paper as [97]
The clusters (surveillance sites) in Winani et al. 2007 received the intervention in a randomized order.
“The clusters (surveillance sites) received the intervention in a randomized order.”
From Applications and implementation considerations for stepped-wedge designs in sub-Saharan Africa: a systematic review (2026) · cites this paper as [97]
The stepped-wedge design in Winani et al. 2007 was chosen to overcome ethical issues related to withholding an effective intervention and logistical issues related to simultaneous implementation in multiple clusters.
“The stepped-wedge design was chosen to overcome ethical issues related to withholding an effective intervention and logistical issues related to simultaneous implementation in multiple clusters.”
From Applications and implementation considerations for stepped-wedge designs in sub-Saharan Africa: a systematic review (2026) · cites this paper as [97]
Newborns whose mothers used the delivery kit in Winani et al. 2007 were 13.1 times less likely to develop cord infection, and mothers who used the kit were 3.2 times less likely to develop puerperal sepsis.
“Newborns whose mothers used the delivery kit were 13.1 times less likely to develop cord infection, and mothers who used the kit were 3.2 times less likely to develop puerperal sepsis”
From Applications and implementation considerations for stepped-wedge designs in sub-Saharan Africa: a systematic review (2026) · cites this paper as [97]
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References 28 · Cited by 72
- Authors
- Winani, S., Wood, S., Coffey, P., Chirwa, T., Mosha, F., & Changalucha, J.
- Affiliations
- Program for Appropriate Technology in Health (US)
- University of London (GB)
- National Institute for Medical Research (TZ)
- Venue
- Journal of Midwifery & Women's Health
- Publisher
- Wiley
- Published
- 2007-01-02
- Volume
- 52
- Issue
- 1
- Pages
- 37-43
- ISSN
- 1526-9523 (ISSN-L)
- 1542-2011
- OpenAlex
- W2140777989
- Cited by
- 72
- References
- 28
- Citations by year
- 2026: 1 · 2024: 5 · 2023: 4 · 2022: 3 · 2021: 2 · 2020: 3 · 2019: 5 · 2018: 2 · 2017: 3 · 2016: 3 · 2015: 7 · 2014: 3 · 2013: 6 · 2012: 7
- FWCI
- 4.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Midwifery & Women s Health (publishedVersion)
- PubMed (publishedVersion)
- LSHTM Research Online (London School of Hygiene and Tropical Medicine) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Global Maternal and Child Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Neonatal and Maternal Infections
- Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
- Keywords
- umbilical infection, puerperal fever, maternal hygiene, postpartum infection prevention, neonatal infection prevention, Mwanza, Tanzania
- MeSH terms
- Adolescent, Adult, Cross-Sectional Studies, Female, Home Childbirth, Humans, Infant Welfare, Infant, Newborn, Health Knowledge, Attitudes, Practice, Maternal Welfare, Midwifery, Pregnancy, Preventive Health Services, Puerperal Infection, Surveys and Questionnaires, Rural Population, Tanzania, Umbilical Cord, Nursing Methodology Research, Infection Control
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