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Cited by 113Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and TreatmentsHistorical and Modern Theater Studies

The DOI matches its Crossref record; 58 of the 61 references it cites were found in a registry or an index.

Mild cognitive impairment in symptomatic and asymptomatic cerebrovascular disease

Popović, Irena Martinić, Šerić, Vesna, Demarin, Vida·2007·Journal of the Neurological Sciences
DOI 10.1016/j.jns.2007.01.029
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Abstract

We tried to evaluate and to compare usefulness of two brief cognitive tests in early detection of cognitive decline in subjects with increased cerebrovascular (CV) risk. As CV risk factors are recognised as important in etiology of dementia, we also aimed to determine the possible associations of specific CV risk factors and cognitive results. Patients (PGs) with first-ever stroke or TIA (N=110) and CV symptoms-free controls (CGs) with CV risk factors present (N=45) matched for age, gender and education level were tested using Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) on admission, at three- and six-month points. In all subjects, detailed CV risk factors profile was assessed. We observed the decrement in cognitive performance during the six-month study period in both groups, more evident if MoCA (p<0.001) than if MMSE was used (p=0.022). Six months after first stroke/TIA 83.6% PGs scored below normal range on MoCA. In PGs, positive associations for cognitive decrement and multiple CV risk factors (>2) were found (p=0.034 for MMSE; p=0.002 for MoCA). In CGs, positive associations were found for cognitive decrement and arterial hypertension with increased IMT values (p<0.001 for MMSE) and for multiple CV risk factors and arterial hypertension (p=0.003 for MoCA). The use of MoCA could aid to early recognition of cognitive deficits in persons with increased CV risk. Individuals with multiple CV risk factors seem to have increased risk of cognitive decline.

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  1. Alexandrov, 1999, Insonation techniques and diagnostic criteria for transcranial Doppler sonography, Acta Clin Croat, 38, 97

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Metadata

Authors
Popović, I. M., Šerić, V., & Demarin, V.
Affiliations
Sisters of Charity Hospital (HR)
Corresponding author
Popović, Irena Martinić
ORCID
Demarin, Vida
Venue
Journal of the Neurological Sciences
Publisher
Elsevier BV
Published
2007-06
Volume
257
Issue
1-2
Pages
185-193
ISSN
0022-510X (ISSN-L)
DOI
10.1016/j.jns.2007.01.029
OpenAlex
W2031608221
Cited by
113
References
61
Citations by year
2026: 2 · 2024: 3 · 2023: 1 · 2022: 4 · 2021: 2 · 2020: 8 · 2019: 3 · 2018: 7 · 2017: 8 · 2016: 8 · 2015: 6 · 2014: 9 · 2013: 12 · 2012: 8
FWCI
4.22
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Journal of the Neurological Sciences (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
  • Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
Keywords
mild cognitive impairment, cerebrovascular disease, stroke, transient ischemic attack, cognitive decline, Montreal Cognitive Assessment, Mini-Mental State Examination, vascular risk factors, hypertension, carotid intima-media thickness, dementia risk, early detection of cognitive decline
MeSH terms
Aged, Brain, Cerebral Arteries, Cerebrovascular Disorders, Cognition Disorders, Dementia, Female, Humans, Hypertension, Male, Mass Screening, Middle Aged, Neuropsychological Tests, Predictive Value of Tests, Prognosis, Risk Factors, Disease Progression

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