The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.
Level of neurotoxic metals in amyotrophic lateral sclerosis: A population-based case–control study
Abstract
The association between exposure to toxic metals and amyotrophic lateral sclerosis (ALS) was explored in a population-based case-control study in the Sardinia island (Italy), a region characterized by elevated rates of ALS cases. In 34 patients with ALS (mean age, 62 ± 10 years) and 30 controls (mean age, 65 ± 11 years), Al, Cd, Hg, Mn and Pb were determined in blood, hair and urine by sector field inductively coupled mass spectrometry. Results indicated that, in blood, concentrations of Al (p=0.045) and Pb were higher (p=0.026) in ALS patients than in control subjects. In hair, a depletion of Al (p=0.006) and Mn (p=0.032) concentrations in ALS subjects respect to controls was found. In urine, no significant differences between cases and controls were observed. Thus, some metals seemed to be associated with ALS degeneration, but a definitive conclusion is still far considering the multiple risk factors (genetic mutations, environmental toxicants and stressors) involved in the disease. Finally, the interpretation that deregulated metal concentrations can be a consequence of the degenerative process, rather than a cause, is also valid.
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“Also, blood lead levels in ALS patients have been reported to be significantly higher than controls.”
From Risk factors for amyotrophic lateral sclerosis: A regional United States case‐control study (2021) · cites this paper as [33]
Citations
Cites
The History and Geography of Human Genes: Abridged paperback Edition
Cavalli-Sforza, L. L., Menozzi, P., & Piazza, A. (2018) · Princeton University Press eBooks · doi:10.2307/j.ctv301gjp · Cited by 3,175
Handbook on the toxicology of metals
(1980) · Environmental Pollution Series A Ecological and Biological · doi:10.1016/0143-1471(80)90008-2 · Cited by 2,868
Kiernan, M. C., Vucic, S., Cheah, B. C., Turner, M. R., Eisen, A., Hardiman, O., Burrell, J. R., & Zoing, M. C. (2011) · The Lancet · doi:10.1016/s0140-6736(10)61156-7 · Cited by 2,603
History and Geography of Human Genes
Piazza, A. (1994) · Advances in Forensic Haemogenetics · doi:10.1007/978-3-642-78782-9_1 · Cited by 1,639
Toxicological profile for lead
U.S. Department of Health and Human Services. Centers for Disease Control and Prevention (U.S.). Agency for Toxic Substances and Disease Registry (2020) · doi:10.15620/cdc:95222 · Cited by 1,336
The history and geography of human genes
(1995) · Choice Reviews Online · doi:10.5860/choice.33-0316 · Cited by 1,312
Handbook on the Toxicology of Metals
(2015) · Elsevier eBooks · doi:10.1016/c2011-0-07884-5 · Cited by 1,228
Chiò, A., Logroscino, G., Traynor, B. J., Collins, J., Simeone, J. C., Goldstein, L. A., & White, L. A. (2013) · Neuroepidemiology · doi:10.1159/000351153 · Cited by 862
Brain Aluminum Distribution in Alzheimer's Disease and Experimental Neurofibrillary Degeneration
Crapper, D. R., Krishnan, S., & Dalton, A. J. (1973) · Science · doi:10.1126/science.180.4085.511 · Cited by 837
Barbosa, F., Tanus-Santos, J. E., Gerlach, R. F., & Parsons, P. J. (2005) · Environmental Health Perspectives · doi:10.1289/ehp.7917 · Cited by 776
Research works printed but not linked: 2
- Albers, 2009, Lead exposure and amyotrophic lateral sclerosis in a Northern California population, Neuroepidemiology, 33, 74
- Rao, 1999, Trace elements in the cerebrospinal fluid in Alzheimer’s disease, Alz Rep, 2, 333
Cited by
Risk factors for amyotrophic lateral sclerosis: A regional United States case‐control study
Andrew, A. S., Bradley, W. G., Peipert, D., Butt, T., Amoako, K., Pioro, E. P., Tandan, R., Novak, J., Quick, A., Pugar, K. D., et al. (2021) · Muscle & Nerve · doi:10.1002/mus.27085 · Cited by 54
Metadata
- Authors
- Bocca, B., Forte, G., Oggiano, R., Clemente, S., Asara, Y., Peruzzu, A., Farace, C., Pala, S., Fois, A. G., Pirina, P., & Madeddu, R.
- Venue
- Journal of the Neurological Sciences
- Publisher
- Elsevier BV
- Published
- 2015-12
- Volume
- 359
- Issue
- 1-2
- Pages
- 11-17
- ISSN
- 0022-510X
- Cited by
- 54
- References
- 88
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
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