Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 54

The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.

Level of neurotoxic metals in amyotrophic lateral sclerosis: A population-based case–control study

Bocca, Beatrice, Forte, Giovanni, Oggiano, Riccardo, Clemente, Simonetta, Asara, Yolande, Peruzzu, Angela, Farace, Cristiano, Pala, Salvatore, Fois, Alessandro Giuseppe, Pirina, Pietro, Madeddu, Roberto·2015·Journal of the Neurological Sciences
DOI 10.1016/j.jns.2015.10.023
Open this paper in CoChat — free account

Abstract

The association between exposure to toxic metals and amyotrophic lateral sclerosis (ALS) was explored in a population-based case-control study in the Sardinia island (Italy), a region characterized by elevated rates of ALS cases. In 34 patients with ALS (mean age, 62 ± 10 years) and 30 controls (mean age, 65 ± 11 years), Al, Cd, Hg, Mn and Pb were determined in blood, hair and urine by sector field inductively coupled mass spectrometry. Results indicated that, in blood, concentrations of Al (p=0.045) and Pb were higher (p=0.026) in ALS patients than in control subjects. In hair, a depletion of Al (p=0.006) and Mn (p=0.032) concentrations in ALS subjects respect to controls was found. In urine, no significant differences between cases and controls were observed. Thus, some metals seemed to be associated with ALS degeneration, but a definitive conclusion is still far considering the multiple risk factors (genetic mutations, environmental toxicants and stressors) involved in the disease. Finally, the interpretation that deregulated metal concentrations can be a consequence of the degenerative process, rather than a cause, is also valid.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.jns.2015.10.023

Cites

88 of 88 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Research works printed but not linked: 2

  1. Albers, 2009, Lead exposure and amyotrophic lateral sclerosis in a Northern California population, Neuroepidemiology, 33, 74
  2. Rao, 1999, Trace elements in the cerebrospinal fluid in Alzheimer’s disease, Alz Rep, 2, 333

Cited by

See all 54

Metadata

Authors
Bocca, B., Forte, G., Oggiano, R., Clemente, S., Asara, Y., Peruzzu, A., Farace, C., Pala, S., Fois, A. G., Pirina, P., & Madeddu, R.
Venue
Journal of the Neurological Sciences
Publisher
Elsevier BV
Published
2015-12
Volume
359
Issue
1-2
Pages
11-17
ISSN
0022-510X
DOI
10.1016/j.jns.2015.10.023
Cited by
54
References
88
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.