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Cited by 172Hip disorders and treatmentsOsteoarthritis Treatment and MechanismsLower Extremity Biomechanics and Pathologies

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Patient-specific analysis of cartilage and labrum mechanics in human hips with acetabular dysplasia

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Henak, C.R., Abraham, C.L., Anderson, A.E., Maas, S.A., Ellis, B.J., Peters, C.L., Weiss, J.A.·2014·Osteoarthritis and Cartilage
DOI 10.1016/j.joca.2013.11.003PMC PMC3946188
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Abstract

Background Acetabular dysplasia is a major predisposing factor for development of hip osteoarthritis (OA), and may result from alterations to chondrolabral loading. Subject-specific finite element (FE) modeling can be used to evaluate chondrolabral mechanics in the dysplastic hip, thereby providing insight into mechanics that precede OA. Objective To evaluate chondrolabral contact mechanics and congruency in dysplastic hips and normal hips using a validated approach to subject-specific FE modeling. Methods FE models of ten subjects with normal acetabula and ten subjects with dysplasia were constructed using a previously validated protocol. Labrum load support, and labrum and acetabular cartilage contact stress and contact area were compared between groups. Local congruency was determined at the articular surface for two simulated activities. Results The labrum in dysplastic hips supported 2.8-4.0 times more of the load transferred across the joint than in normal hips. Dysplastic hips did not have significantly different congruency in the primary load-bearing regions than normal hips, but were less congruent in some unloaded regions. Normal hips had larger cartilage contact stress than dysplastic hips in the few regions that had significant differences. Conclusions The labrum in dysplastic hips has a far more significant role in hip mechanics than it does in normal hips. The dysplastic hip is neither less congruent than the normal hip, nor subjected to elevated cartilage contact stresses. This study supports the concept of an outside-in pathogenesis of OA in dysplastic hips and that the labrum in dysplastic hips should be preserved during surgery.

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  • Stress concentration on the limited articular surface for weight-bearing and dynamic joint instability are considered significant biomechanical factors that cause joint degeneration in younger patients.

    “Stress concentration on the limited articular surface for weight-bearing and dynamic joint instability are considered significant biomechanical factors that cause joint degeneration in younger patients [9].”

    From Femoral head translation in borderline and definite dysplastic hips during weight‐bearing: 2D/3D image registration analysis (2023) · cites this paper as [9]

    The Introduction links acetabular dysplasia and altered hip mechanics to osteoarthritis, but the Discussion expressly rejects increased cartilage contact stress as the explanation found in this study: the labrum carries much of the load, and cartilage stresses in dysplastic hips were not increased relative to normal hips. The paper does not establish dynamic joint instability as a cause of degeneration in younger patients. No page numbers are available in our copy. (LLM, conf=0.86)

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Metadata

Authors
Henak, C. R., Abraham, C. L., Anderson, A. E., Maas, S. A., Ellis, B. J., Peters, C. L., & Weiss, J. A.
Affiliations
University of Utah (US)
Corresponding author
  • Henak, C.R.
  • Abraham, C.L.
  • Anderson, A.E.
  • Maas, S.A.
  • Ellis, B.J.
  • Peters, C.L.
  • Weiss, J.A.
ORCID
Venue
Osteoarthritis and Cartilage
Publisher
Elsevier BV
Published
2014-02
Volume
22
Issue
2
Pages
210-217
ISSN
1063-4584 (ISSN-L)
DOI
10.1016/j.joca.2013.11.003
PMC
PMC3946188
OpenAlex
W2088544607
Cited by
172
References
0
Citations by year
2026: 10 · 2025: 11 · 2024: 10 · 2023: 13 · 2022: 20 · 2021: 19 · 2020: 16 · 2019: 16 · 2018: 15 · 2017: 11 · 2016: 13 · 2015: 9 · 2014: 8
FWCI
9.87
Type
journal article
Language
en
Open access
Licence
Locations
  • Osteoarthritis and Cartilage (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
NIH (R01AR053344, R01GM083925)
Topics
  • Health Sciences › Medicine › Surgery › Hip disorders and treatments
  • Health Sciences › Medicine › Rheumatology › Osteoarthritis Treatment and Mechanisms
  • Physical Sciences › Engineering › Biomedical Engineering › Lower Extremity Biomechanics and Pathologies
Keywords
acetabular dysplasia, hip osteoarthritis, labrum, acetabular cartilage, joint congruency, hip biomechanics
MeSH terms
Acetabulum, Adult, Cartilage, Articular, Female, Hip Dislocation, Humans, Male, Models, Biological, Stress, Mechanical, Tomography, X-Ray Computed, Case-Control Studies, Weight-Bearing, Finite Element Analysis, Young Adult

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