The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index; 15 of the 20 sources its claims cite were checked for support.
Femoral head translation in borderline and definite dysplastic hips during weight‐bearing: 2D/3D image registration analysis
Open accessAbstract
Abstract Purpose The aims of this study were to 1) assess femoral head translation during weight‐bearing in symptomatic developmental dysplasia of the hip (DDH) and 2) compare it between borderline DDH and definite DDH. Methods The study included four individuals with borderline DDH and nine with definite DDH, scheduled for periacetabular osteotomy. Anteroposterior X‐ray images of the hip joint were obtained in the standing position, and computed tomography images of the pelvis were obtained in the supine position. Femoral head translation from the supine to a standing position was measured using 2D/3D X‐ray image registration. Results From a supine to a standing position, the femoral head translated 0.3 mm laterally, 0.5 mm anteriorly, and 0.5 mm superiorly on average. The mean femoral head translation in 3D between the supine and standing positions was 1.5 mm. The 3D femoral head translation in the borderline DDH group was significantly greater than that in the definite DDH group. In the definite DDH group, there was a significant correlation between the center edge (CE) angle and 3D femoral head translation ( ρ = ‐0.78, P = 0.012). Conclusions Symptomatic DDH showed femoral head translation in the anterior, lateral, and superior directions during weight‐bearing. In definite DDH, the amount of femoral head translation was negatively correlated with the CE angle. The amount of 3D translation in patients with borderline DDH was larger than that in definite DDH. Dynamic joint instability during weight‐bearing was observed in borderline DDH as well as definite DDH. Treatment to enhance joint stability during weight‐bearing is important in both cases.
Overview
AI snapshot
Written from the paper’s full text.
TL;DR
In symptomatic developmental dysplasia of the hip (DDH), the femoral head translates anteriorly, laterally, and superiorly during weight-bearing, with a mean 3D translation of 1.5 mm from supine to standing. Borderline DDH showed greater 3D translation than definite DDH, and in definite DDH translation was negatively correlated with the center edge (CE) angle.
Key findings
- From supine to standing, the femoral head translated 0.3 mm laterally, 0.5 mm anteriorly, and 0.5 mm superiorly on average; mean 3D femoral head translation was 1.5 mm.
- 3D femoral head translation was significantly greater in borderline DDH than in definite DDH (2.2 mm vs 1.2 mm).
- In definite DDH, the CE angle correlated with 3D femoral head translation (ρ = -0.78, P = 0.012); all morphological parameters except PASA and FEAR index showed significant correlations with 3D translation in this group.
- No morphological factors were correlated with 3D femoral head translation among all subjects. Postoperative JOA scores improved from 74 to 98 in borderline DDH and from 74 to 96 in definite DDH.
Methods
- Prospective cohort study of 13 symptomatic hips from 13 patients with DDH who underwent rotational acetabular osteotomy; 4 hips were classified as borderline DDH (18° ≤ CE angle < 25°) and 9 as definite DDH (CE angle < 18°).
- Standing anteroposterior hip X-rays and supine pelvic CT images were used; femoral head translation from supine to standing was measured with 2D/3D X-ray image registration, using the anterior pelvic plane coordinate system.
- An in vitro porcine hip validation study assessed registration accuracy; statistical comparisons used Student’s t-test or Mann–Whitney U test, and correlations used Pearson or Spearman coefficients, with P < 0.05.
Limitations
- Stated by the authors: no normal hip control was evaluated to avoid radiation exposure; the definition of borderline dysplasia remains unclear (they used 18° ≤ CE angle < 25°, while 20° ≤ CE angle < 25° is also common); the number of cases was small despite meeting the power analysis minimum; and the measured translations were small relative to the method’s accuracy, with in vitro validation indicating measurement accuracy of < 1 mm.
- Evident from the text: all participants were female, so findings may not generalize to male patients; the study assessed supine-to-standing translation rather than dynamic gait or other weight-bearing activities.
Model-written summary. Check it against the paper before relying on it.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
15 of 20 cited sources checked · 10 supported · 1 flagged · accuracy not yet measured
- Premisecitation
Stress concentration on the limited articular surface for weight-bearing and dynamic joint instability are considered significant biomechanical factors that cause joint degeneration in younger patients.
“Stress concentration on the limited articular surface for weight-bearing and dynamic joint instability are considered significant biomechanical factors that cause joint degeneration in younger patients [9].”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [9] Henak CR Abraham CL Anderson AE Maas SA Ellis BJ Peters CL Patient-specific analysis of cartilage and labrum mechanics in human hips with acetabular dysplasia Osteoarthritis Cartilage 2014 22 210 217 10.1016/j.joca.2013.11.003 24269633 PMC3946188 source
The Introduction links acetabular dysplasia and altered hip mechanics to osteoarthritis, but the Discussion expressly rejects increased cartilage contact stress as the explanation found in this study: the labrum carries much of the load, and cartilage stresses in dysplastic hips were not increased relative to normal hips. The paper does not establish dynamic joint instability as a cause of degeneration in younger patients. No page numbers are available in our copy. (LLM, conf=0.86)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measured
- Premisecitation
Few studies have evaluated the in vivo dynamic instability in DDH during weight-bearing.
“However, few studies have evaluated the in vivo dynamic instability in DDH during weight-bearing [1, 18].”
Quote in the paperSubstantial claim2 of 2 sources checked- cites [1] Akiyama K Sakai T Koyanagi J Yoshikawa H Sugamoto K Evaluation of translation in the normal and dysplastic hip using three-dimensional magnetic resonance imaging and voxel-based registration Osteoarthritis Cartilage 2011 19 700 710 10.1016/j.joca.2011.01.017 21315165 source
The Introduction says there have been few in vivo studies of hip instability, supporting the scarcity claim. The Discussion describes an earlier gait-cycle study, but does not establish that the few studies evaluated instability specifically during weight-bearing; it also says this paper's own MRI measurements were static and could not assess functional effects during daily activities. (LLM, conf=0.85)
Experimental — accuracy not yet measured - cites [18] Sato T Tanino H Nishida Y Ito H Matsuno T Banks SA Dynamic femoral head translations in dysplastic hips Clin Biomech 2017 46 40 45 10.1016/j.clinbiomech.2017.05.003 28501788 source
- Study design and conductcitation
The degree of femoral head translation during weight-bearing was small compared with the measurement accuracy of the computational 2D/3D image registration method.
“Finally, the degree of femoral head translation during weight-bearing was small compared with the measurement accuracy of our computational 2D/3D image registration method (root mean square error of 0.2 mm in translation and 0.2° in rotation in porcine patellar bones [11]).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [11] Ishimaru M Shiraishi Y Ikebe S Three-dimensional motion analysis of the patellar component in total knee arthroplasty by the image matching method using image correlations J Orthop Res 2014 32 619 626 10.1002/jor.22596 24522960 source
- Rests on an assumption: The 2D/3D image registration method's accuracy, validated in vitro on porcine bones, applies to in vivo human DDH hips.
- Interpretationown data
The values of femoral head translation during weight-bearing in DDH are similar to those reported in previous studies on dynamic instability of definite DDH.
“In this study, the femoral head translation during weight-bearing in DDH ranged from 0.5 to 2.3 mm, similar values to those reported in previous studies on dynamic instability of definite DDH [1, 18].”
Quote in the paperSubstantial claim2 of 2 sources checked- cites [1] Akiyama K Sakai T Koyanagi J Yoshikawa H Sugamoto K Evaluation of translation in the normal and dysplastic hip using three-dimensional magnetic resonance imaging and voxel-based registration Osteoarthritis Cartilage 2011 19 700 710 10.1016/j.joca.2011.01.017 21315165 source
The Results report millimetre-scale femoral-head translation in dysplastic hips, including 0.76–2.39 mm from neutral to flexion. But the Discussion says the measurements came from static MRI positions and could not evaluate functional effects during daily activity. The paper therefore supports a similarity in magnitude, not translation measured during weight-bearing or dynamic instability. (LLM, conf=0.88)
Experimental — accuracy not yet measured - cites [18] Sato T Tanino H Nishida Y Ito H Matsuno T Banks SA Dynamic femoral head translations in dysplastic hips Clin Biomech 2017 46 40 45 10.1016/j.clinbiomech.2017.05.003 28501788 source
- Rests on an assumption: The 2D/3D image registration method's accuracy, validated in vitro on porcine bones, applies to in vivo human DDH hips.
- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
- Premisecitation
The image-matching method had a root mean square error of 0.2 mm in translation and 0.2° in rotation when measuring the patellar bone of a fresh-frozen porcine knee joint.
“The accuracy of measurements of the patellar bone of a fresh-frozen porcine knee joint yielded a root mean square error of 0.2 mm in translation and 0.2° in rotation [11].”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [11] Ishimaru M Shiraishi Y Ikebe S Three-dimensional motion analysis of the patellar component in total knee arthroplasty by the image matching method using image correlations J Orthop Res 2014 32 619 626 10.1002/jor.22596 24522960 source
- Study design and conductreasoning
A sample of four borderline DDH and eight definite DDH cases is required to have 80% power to detect a true mean difference of 1 mm between groups, with a type I error probability of 0.05, assuming a standard deviation of 0.5 mm.
“Consequently, if the true mean difference between the borderline DDH and definite DDH groups is 1 mm, a sample of four borderline DDH and eight definite DDH cases is required to have a statistical power of 80% to reject the null hypothesis that the population means of two groups are equal, with a type I error probability of 0.05.”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [1] Akiyama K Sakai T Koyanagi J Yoshikawa H Sugamoto K Evaluation of translation in the normal and dysplastic hip using three-dimensional magnetic resonance imaging and voxel-based registration Osteoarthritis Cartilage 2011 19 700 710 10.1016/j.joca.2011.01.017 21315165 source
The Patients and study design section describes normal and dysplastic hips, not borderline and definite DDH groups. The Statistical analysis section sets a significance threshold of P < 0.05 but gives no power or sample-size calculation. Searches for the proposed group sizes, 1 mm difference, 80% power, and assumed 0.5 mm standard deviation found no passage addressing the claim. (LLM, conf=0.75)
Experimental — accuracy not yet measured
- Findingown data
Among all DDH subjects, no morphological factors were correlated with 3D femoral head translation.
“No morphological factors were correlated with 3D femoral head translation among whole subjects (Table 3).”
Quote in the paperSubstantial claim- Rests on an assumption: The 2D/3D image registration method's accuracy, validated in vitro on porcine bones, applies to in vivo human DDH hips.
- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
- Findingown data
In the definite DDH group, the CE angle was significantly correlated with 3D femoral head translation (ρ = -0.78, P = 0.012).
“In the definite DDH group, there was a significant correlation between the center edge (CE) angle and 3D femoral head translation (ρ = -0.78, P = 0.012).”
- Also stated in: § In vivo study · plain
“The CE angle showed a significant correlation with 3D femoral head translation (ρ = -0.78, P = 0.012) (Fig. 4).”
- Also stated in: § Conclusions · plain
“In definite DDH, the amount of femoral head translation was negatively correlated with the CE angle.”
Quote in the paperSubstantial claim- Rests on an assumption: The 2D/3D image registration method's accuracy, validated in vitro on porcine bones, applies to in vivo human DDH hips.
- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
- Also stated in: § In vivo study · plain
- Findingown data
In the definite DDH group, all morphological parameters except PASA and FEAR index showed a significant correlation with 3D femoral head translation.
“In contrast, in the definite DDH group, all morphological parameters, except for the PASA and FEAR index, showed a significant correlation with 3D femoral head translation (Table 3).”
Quote in the paperSubstantial claim- Rests on an assumption: The 2D/3D image registration method's accuracy, validated in vitro on porcine bones, applies to in vivo human DDH hips.
- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
- Findingown data
The femoral head translation during weight-bearing in DDH ranged from 0.5 to 2.3 mm.
“In this study, the femoral head translation during weight-bearing in DDH ranged from 0.5 to 2.3 mm, similar values to those reported in previous studies on dynamic instability of definite DDH [1, 18].”
Quote in the paperSubstantial claim- Rests on an assumption: The 2D/3D image registration method's accuracy, validated in vitro on porcine bones, applies to in vivo human DDH hips.
- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
- Findingown data
The 3D femoral head translation in the borderline DDH group was significantly greater than in the definite DDH group (2.2 mm vs 1.2 mm).
“The 3D femoral head translation in the borderline DDH group was significantly greater than that in the definite DDH group.”
- Also stated in: § In vivo study · plain
“The 3D femoral head translation in the borderline DDH group was significantly greater than that in the definite DDH group (2.2 mm for borderline DDH vs 1.2 mm for definite DDH).”
- Also stated in: § Conclusions · plain
“The amount of 3D translation in patients with borderline DDH was larger than that in definite DDH.”
Quote in the paperSubstantial claim- Rests on an assumption: The 2D/3D image registration method's accuracy, validated in vitro on porcine bones, applies to in vivo human DDH hips.
- Rests on an assumption: The supine position provides a neutral reference for measuring femoral head translation.
- Rests on an assumption: The standing position represents the weight-bearing condition relevant to dynamic hip instability.
- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
- Also stated in: § In vivo study · plain
- Study design and conductnone given
The femoral head translation during weight-bearing in symptomatic DDH could be measured using the computational 2D/3D image registration method.
“At least, we consider that the femoral head translation during weight-bearing in symptomatic DDH could be measured using our computational 2D/3D image registration method.”
Quote in the paperSubstantial claim- Rests on an assumption: The 2D/3D image registration method's accuracy, validated in vitro on porcine bones, applies to in vivo human DDH hips.
- Interpretationown data
Symptomatic DDH showed femoral head translation in the anterior, lateral, and superior directions during weight-bearing.
“Symptomatic DDH showed femoral head translation in the anterior, lateral, and superior directions during weight-bearing.”
- Also stated in: § Conclusions · plain
“In symptomatic DDH, femoral head translation in the anterior, lateral, and superior directions was observed during weight-bearing.”
Quote in the paperSubstantial claim- Rests on an assumption: Femoral head translation measured from the supine to the standing position reflects dynamic joint instability during weight-bearing.
- Rests on an assumption: The standing position represents the weight-bearing condition relevant to dynamic hip instability.
- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
- Also stated in: § Conclusions · plain
- It may state two separate claims as one. 10
- Probably not a substantial claim. 9
- The quote only partly states this claim. 2
It may state two separate claims as one.
InterpretationcitationThe CE angle was the determinant for 3D-translation from the neutral to the Patrick position in Akiyama et al., which coincides with our results for definite DDH.
“The CE angle was the determinant for 3D-translation from the neutral to the Patrick position, which coincides with our results for definite DDH.”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [1] Akiyama K Sakai T Koyanagi J Yoshikawa H Sugamoto K Evaluation of translation in the normal and dysplastic hip using three-dimensional magnetic resonance imaging and voxel-based registration Osteoarthritis Cartilage 2011 19 700 710 10.1016/j.joca.2011.01.017 21315165 source
- Rests on an assumption: The 2D/3D image registration method's accuracy, validated in vitro on porcine bones, applies to in vivo human DDH hips.
- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
It may state two separate claims as one.
InterpretationcitationRegression analyses in Sato et al. showed significant correlations between maximum femoral head translation and the CE angle, AHI, and ARO, which coincides with our results for definite DDH.
“Regression analyses showed significant correlations between maximum femoral head translation and the CE angle, AHI, and ARO, which coincides with our results for definite DDH.”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [18] Sato T Tanino H Nishida Y Ito H Matsuno T Banks SA Dynamic femoral head translations in dysplastic hips Clin Biomech 2017 46 40 45 10.1016/j.clinbiomech.2017.05.003 28501788 source
- Rests on an assumption: The 2D/3D image registration method's accuracy, validated in vitro on porcine bones, applies to in vivo human DDH hips.
- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
Probably not a substantial claim.
PremisecitationHip joint stabilization relies on acetabular bony coverage and integrity of soft tissues, including the acetabular labrum, ligamentum teres, and capsular structures.
“Hip joint stabilization relies on acetabular bony coverage and integrity of soft tissues, including the acetabular labrum, ligamentum teres, and capsular structures [13].”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [13] Kalisvaart MM Safran MR Microinstability of the hip-it does exist: etiology, diagnosis and treatment J Hip Preserv Surg 2015 2 123 135 10.1093/jhps/hnv017 27011829 PMC4718498 source
Probably not a substantial claim. It may state two separate claims as one.
PremisecitationDynamic instability of the hip joint is characterized by excessive femoral head translation within the acetabulum, determined by bone morphology and integrity and laxity of surrounding soft tissues.
“Dynamic instability of the hip joint is characterized by excessive femoral head translation within the acetabulum [16], which is determined by the bone morphology and integrity and laxity of surrounding soft tissues, including the labrum, capsular-ligamentous complex, and ligamentous teres.”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [16] Neira A Amenabar T Cristi-Sanchez I Evaluation of atraumatic hip instability measured by triaxial accelerometry during walking J Hip Preserv Surg 2019 6 134 139 10.1093/jhps/hnz018 31660198 PMC6662898 source
Probably not a substantial claim. It may be too vague to check against evidence.
PremisecitationThe optimal evaluation method of dynamic hip instability remains unclear.
“Much previous research has debated the morphological characteristics to diagnose hip instability; however, the optimal evaluation method of dynamic hip instability remains unclear [2, 4, 17, 20, 22, 23].”
Quote in the paperNot a substantial claim2 of 3 sources checked- cites [2] Batailler C Weidner J Wyatt M Pfluger D Beck M Is the Femoro-Epiphyseal Acetabular Roof (FEAR) index on MRI a relevant predictive factor of instability in a borderline dysplastic hip? Bone Joint J 2019 101-B 1578 1584 10.1302/0301-620X.101B12.BJJ-2019-0502.R1 31787002 source
- cites [4] Dangin A Tardy N Wettstein M May O Bonin N Microinstability of the hip: a review Orthop Traumatol Surg Res 2016 102 S301 S309 10.1016/j.ostr.2016.09.002 27744000 source
- cites [17] Packer JD Cowan JB Rebolledo BJ Shibata KR Riley GM Finlay AK The Cliff Sign: A New Radiographic Sign of Hip Instability Orthop J Sports Med 2018 12 6 2325967118807176 10.1177/2325967118807176 PMC6240982 30480017 source
It may state two separate claims as one.
PremisecitationDamage to the labrum and cartilage, together with lack of acetabular bony coverage and inherent soft tissue laxity, can contribute to various degrees of dynamic instability of the hip joint and cause progressive osteoarthritic changes.
“This damage, together with the lack of acetabular bony coverage and inherent soft tissue laxity, can contribute to various degrees of dynamic instability of the hip joint and cause progressive osteoarthritic changes [8, 12, 19].”
Quote in the paperSubstantial claim1 of 3 sources checked- cites [8] Han S Alexander JW Thomas VS Choi J Harris JD Doherty DB Does capsular laxity lead to microinstability of the native hip? Am J Sports Med 2018 46 1315 1323 10.1177/0363546518755717 29505731 source
- cites [12] Jacobsen S Sonne-Holm S Hip dysplasia: a significant risk factor for the development of hip osteoarthritis A cross-sectional survey Rheumatology (Oxford) 2005 44 211 218 10.1093/rheumtology/keh436 15479751 source
The Discussion (page unavailable) says reduced load-transferring area in dysplastic hips may lead to degeneration and reports an association between hip dysplasia and osteoarthritis. It does not address labral or cartilage damage, soft-tissue laxity, or dynamic instability as the proposed mechanism. (LLM, conf=0.86)
Experimental — accuracy not yet measured - cites [19] Smith MV Panchal HB Ruberte Thiele RA Sekiya JK Effect of acetabular labrum tears on hip stability and labral strain in a joint compression model Am J Sports Med 2011 39 Suppl 103S S110 10.1177/0363546511400981 21709039 source
Probably not a substantial claim. The paper’s conclusions may not depend on it.
Findingnone givenRotational acetabular osteotomy improved the symptoms of four patients with borderline DDH.
“Rotational acetabular osteotomy improved the symptoms of four patients with borderline DDH, suggesting that a slight variation in acetabular coverage between normal and borderline dysplastic hips could influence hip instability, but not mechanical stress concentration, in some patients.”
Quote in the paperNot a substantial claim- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
The quote only partly states this claim.
Findingown dataThe mean 3D femoral head translation between the supine and standing positions was 1.5 mm in symptomatic DDH.
“The mean femoral head translation in 3D between the supine and standing positions was 1.5 mm.”
- Also stated in: § In vivo study · plain
“The mean femoral head translation in 3D between the supine and standing positions was 1.5 mm (Table 2).”
Quote in the paperSubstantial claim- Rests on an assumption: The 2D/3D image registration method's accuracy, validated in vitro on porcine bones, applies to in vivo human DDH hips.
- Rests on an assumption: The supine position provides a neutral reference for measuring femoral head translation.
- Rests on an assumption: The standing position represents the weight-bearing condition relevant to dynamic hip instability.
- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
- Also stated in: § In vivo study · plain
The quote only partly states this claim.
Findingown dataIn symptomatic DDH, from a supine to a standing position, the femoral head translated on average 0.3 mm laterally, 0.5 mm anteriorly, and 0.5 mm superiorly.
“From a supine to a standing position, the femoral head translated 0.3 mm laterally, 0.5 mm anteriorly, and 0.5 mm superiorly on average.”
- Also stated in: § In vivo study · plain
“From the supine to standing position, the femoral head translated 0.3 mm laterally, 0.5 mm anteriorly, and 0.5 mm superiorly on average.”
Quote in the paperSubstantial claim- Rests on an assumption: The 2D/3D image registration method's accuracy, validated in vitro on porcine bones, applies to in vivo human DDH hips.
- Rests on an assumption: The supine position provides a neutral reference for measuring femoral head translation.
- Rests on an assumption: The standing position represents the weight-bearing condition relevant to dynamic hip instability.
- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
- Also stated in: § In vivo study · plain
Probably not a substantial claim.
InterpretationreasoningThe degree of inherent joint laxity may influence susceptibility to joint instability.
“The degree of inherent joint laxity may influence susceptibility to joint instability.”
Quote in the paperSubstantial claim- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
InterpretationreasoningSoft tissue laxity, in addition to labral and cartilage damage, can affect hip joint stabilization.
“Soft tissue laxity, in addition to labral and cartilage damage, can affect hip joint stabilization.”
Quote in the paperNot a substantial claimIt may state two separate claims as one.
Interpretationown dataDynamic joint instability during weight-bearing was observed in borderline DDH as well as definite DDH.
“Dynamic joint instability during weight-bearing was observed in borderline DDH as well as definite DDH.”
Quote in the paperSubstantial claim- Rests on an assumption: Femoral head translation measured from the supine to the standing position reflects dynamic joint instability during weight-bearing.
- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
It may state two separate claims as one.
Interpretationown dataThe results suggest that hip bony morphology and inherent soft tissue laxity vary among dysplastic hips, and both contribute significantly to joint stability.
“The results of this study suggest that hip bony morphology and inherent soft tissue laxity vary among dysplastic hips, both of which contribute significantly to joint stability.”
Quote in the paperSubstantial claim- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
It may state two separate claims as one.
InterpretationreasoningA slight variation in acetabular coverage between normal and borderline dysplastic hips could influence hip instability, but not mechanical stress concentration, in some patients.
“Rotational acetabular osteotomy improved the symptoms of four patients with borderline DDH, suggesting that a slight variation in acetabular coverage between normal and borderline dysplastic hips could influence hip instability, but not mechanical stress concentration, in some patients.”
Quote in the paperNot a substantial claim- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
It may state two separate claims as one.
Interpretationown dataThe finding of greater dynamic hip instability during weight-bearing in borderline DDH than in definite DDH supports the hypothesis that the etiology of borderline DDH is instability.
“In this study, higher dynamic hip instability during weight-bearing was found more commonly in borderline DDH than in definite DDH, which supports the hypothesis that the etiology of borderline DDH is instability.”
Quote in the paperSubstantial claim- Rests on an assumption: Femoral head translation measured from the supine to the standing position reflects dynamic joint instability during weight-bearing.
- Rests on an assumption: The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
Probably not a substantial claim.
Study design and conductreasoningThe study did not evaluate femoral head translation during weight-bearing of normal hip joints as a control.
“First, we did not evaluate femoral head translation during weight-bearing of the normal hip joints as a control to avoid the effects of radiation exposure.”
Quote in the paperSubstantial claimProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
Study design and conductown dataThe number of cases was small, despite being the minimum required number according to the power analysis.
“Third, the number of cases was small, despite being the minimum required number according to our power analysis.”
Quote in the paperNot a substantial claimProbably not a substantial claim. The paper’s conclusions may not depend on it.
PremisecitationThe definition of borderline dysplasia remains unclear.
“Second, the definition of borderline dysplasia remains unclear.”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [5] Domb BG Stake CE Lindner D El-Bitar Y Jackson TJ Arthroscopic capsular plication and labral preservation in borderline hip dysplasia: two-year clinical outcomes of a surgical approach to a challenging problem Am J Sports Med 2013 41 2591 2598 10.1177/0363546513499154 23956133 source
- cites [7] Fukui K Briggs KK Trinidade CAC Philippon MJ Outcomes after labral repair in patients with femoroacetabular impingement and borderline dysplasia Arthroscopy 2015 31 2371 2379 10.1016/j.arthro.2015.06.028 26315056 source
It may state two separate claims as one.
Study design and conductown dataThe 2D/3D X-ray image registration method had translational errors of -0.69 mm (X), 0.21 mm (Y), -0.09 mm (Z) and rotational errors of -0.10° (X), -0.37° (Y), 0.13° (Z) in an in vitro porcine hip validation.
“The translational and rotational errors of the 2D/3D X-ray image registration were -0.10° and -0.69 mm for the X-axis direction, -0.37° and 0.21 mm for the Y-axis direction, and 0.13° and -0.09 mm for the Z-axis direction, respectively.”
- Also stated in: § Discussion · hedged
“The in vitro validation study using porcine hip bones, presented herein, also indicated a measurement accuracy of < 1 mm.”
Quote in the paperNot a substantial claim- Also stated in: § Discussion · hedged
The paper relies on this without support.
Femoral head translation measured from the supine to the standing position reflects dynamic joint instability during weight-bearing.
“Dynamic joint instability during weight-bearing was observed in borderline DDH as well as definite DDH.”
The paper relies on this without support.
The 2D/3D image registration method's accuracy, validated in vitro on porcine bones, applies to in vivo human DDH hips.
“At least, we consider that the femoral head translation during weight-bearing in symptomatic DDH could be measured using our computational 2D/3D image registration method.”
The paper relies on this without support.
The supine position provides a neutral reference for measuring femoral head translation.
“The direction and distance of movement of the femoral head center from the supine to the standing position were measured (Fig. 3).”
The paper relies on this without support.
The standing position represents the weight-bearing condition relevant to dynamic hip instability.
“Anteroposterior X-ray images of the hip joint were obtained with the patient in the standing position using an X-ray flat panel detector system (FPD, Zexira®; Toshiba, Tokyo, Japan).”
The paper relies on this without support.
The study sample of symptomatic DDH hips is representative of the broader population of symptomatic DDH.
“In this prospective cohort study, we evaluated 13 symptomatic hips from 13 patients with DDH who underwent rotational acetabular osteotomy between April 2018 and April 2022 at our institution.”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Mean age differs between the text and Table 1
MinorThe text reports a mean age of 30.8 years, while Table 1 reports 29.8 years for the same 13 patients. The ages listed individually in Table 2 average 29.8 years.
“The mean age was 30.8 (range, 17–48) years”
“| Age (years) | 29.8 ± 11.0 | 32.2 ± 10.4 | 24.0 ± 8.7 | 0.25 |”
Borderline-group sex count omits one patient
MinorTable 1 lists four patients in the borderline DDH group but gives its female/male count as 3/0. The text states that all participants were female.
“| Sex (female/male) | 13/0 | 9/0 | 3/0 | |”
“| Number of patients | 13 | 9 | 4 | |”
Citations
Cites
Domb, B. G., Stake, C. E., Lindner, D., El-Bitar, Y., & Jackson, T. J. (2013) · The American Journal of Sports Medicine · doi:10.1177/0363546513499154 · Cited by 318
Jacobsen, S., & Sonne‐Holm, S. (2004) · Lara D. Veeken · doi:10.1093/rheumatology/keh436 · Cited by 316 · cited 1×
“This damage, together with the lack of acetabular bony coverage and inherent soft tissue laxity, can contribute to various degrees of dynamic instability of the hip joint and cause progressive osteoarthritic changes [8, 12, 19].”
BackgroundJacobsen, S., & Sonne-Holm, S. (2005) · Rheumatology · doi:10.1093/rheumtology/keh436 · Cited by 316
Microinstability of the hip--it does exist: etiology, diagnosis and treatment
Kalisvaart, M. M., & Safran, M. R. (2015) · Journal of Hip Preservation Surgery · doi:10.1093/jhps/hnv017 · Cited by 210 · cited 1×
“Hip joint stabilization relies on acetabular bony coverage and integrity of soft tissues, including the acetabular labrum, ligamentum teres, and capsular structures [13].”
BackgroundWyatt, M. C., Weidner, J., Pfluger, D. H., & Beck, M. (2016) · Clinical Orthopaedics and Related Research · doi:10.1007/s11999-016-5137-0 · Cited by 184 · cited 2×
“In addition, we evaluated the breakdown in Shenton’s line, Cliff sign and femoro-epiphyseal acetabular roof (FEAR) index [2, 17, 20, 22, 23].”
BackgroundMethodPatient-specific analysis of cartilage and labrum mechanics in human hips with acetabular dysplasia
Henak, C. R., Abraham, C. L., Anderson, A. E., Maas, S. A., Ellis, B. J., Peters, C. L., & Weiss, J. A. (2014) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2013.11.003 · Cited by 172 · cited 1×
“Stress concentration on the limited articular surface for weight-bearing and dynamic joint instability are considered significant biomechanical factors that cause joint degeneration in younger patients [9].”
BackgroundEffect of Acetabular Labrum Tears on Hip Stability and Labral Strain in a Joint Compression Model
Smith, M. V., Panchal, H. B., Ruberte Thiele, R. A., & Sekiya, J. K. (2011) · The American Journal of Sports Medicine · doi:10.1177/0363546511400981 · Cited by 117 · cited 1×
“This damage, together with the lack of acetabular bony coverage and inherent soft tissue laxity, can contribute to various degrees of dynamic instability of the hip joint and cause progressive osteoarthritic changes [8, 12, 19].”
BackgroundOutcomes After Labral Repair in Patients With Femoroacetabular Impingement and Borderline Dysplasia
Fukui, K., Briggs, K. K., Trindade, C. A. C., & Philippon, M. J. (2015) · Arthroscopy · doi:10.1016/j.arthro.2015.06.028 · Cited by 113 · cited 1×
“[5], while borderline dysplasia is often defined as 20° ≤ CE angle 25° [7].”
BackgroundMicroinstability of the hip: A review
Dangin, A., Tardy, N., Wettstein, M., May, O., & Bonin, N. (2016) · Orthopaedics & Traumatology: Surgery & Research · doi:10.1016/j.otsr.2016.09.002 · Cited by 100 · cited 1×
“Much previous research has debated the morphological characteristics to diagnose hip instability; however, the optimal evaluation method of dynamic hip instability remains unclear [2, 4, 17, 20, 22, 23].”
BackgroundDoes Capsular Laxity Lead to Microinstability of the Native Hip?
Han, S., Alexander, J. W., Thomas, V. S., Choi, J., Harris, J. D., Doherty, D. B., Jeffers, J. R. T., & Noble, P. C. (2018) · The American Journal of Sports Medicine · doi:10.1177/0363546518755717 · Cited by 90 · cited 1×
“This damage, together with the lack of acetabular bony coverage and inherent soft tissue laxity, can contribute to various degrees of dynamic instability of the hip joint and cause progressive osteoarthritic changes [8, 12, 19].”
BackgroundThe Cliff Sign: A New Radiographic Sign of Hip Instability
Packer, J. D., Cowan, J. B., Rebolledo, B. J., Shibata, K. R., Riley, G. M., Finlay, A. K., & Safran, M. R. (2018) · Orthopaedic Journal of Sports Medicine · doi:10.1177/2325967118807176 · Cited by 56 · cited 2×
“In addition, we evaluated the breakdown in Shenton’s line, Cliff sign and femoro-epiphyseal acetabular roof (FEAR) index [2, 17, 20, 22, 23].”
BackgroundMethodMibe, J., Imakiire, A., Watanabe, T., et al. (2005) · Journal of Orthopaedic Science · doi:10.1007/s00776-004-0845-9 · Cited by 52
Akiyama, K., Sakai, T., Koyanagi, J., Yoshikawa, H., & Sugamoto, K. (2011) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2011.01.017 · Cited by 48 · cited 4×
“The calculation was based on a previous study, in which the femoral head translation during motion within each participant group was normally distributed with a standard deviation of 0.5 mm [1].”
BackgroundMethodResultInfluentialTruntzer, J. N., Hoppe, D. J., Shapiro, L. M., & Safran, M. R. (2019) · The American Journal of Sports Medicine · doi:10.1177/0363546519876105 · Cited by 45 · cited 2×
“In addition, we evaluated the breakdown in Shenton’s line, Cliff sign and femoro-epiphyseal acetabular roof (FEAR) index [2, 17, 20, 22, 23].”
BackgroundMethodDiagnosing Hip Microinstability: an international consensus study using the Delphi methodology
Khanduja, V., Darby, N., O’Donnell, J., et al. (2022) · Knee Surgery Sports Traumatology Arthroscopy · doi:10.1007/s00167-022-06933-4 · Cited by 45
Microinstability of the hip: a systematic review of the imaging findings
Woodward, R. M., Vesey, R. M., Bacon, C. J., White, S., Brick, M. J., & Blankenbaker, D. G. (2020) · Skeletal Radiology · doi:10.1007/s00256-020-03516-7 · Cited by 44 · cited 2×
“In addition, we evaluated the breakdown in Shenton’s line, Cliff sign and femoro-epiphyseal acetabular roof (FEAR) index [2, 17, 20, 22, 23].”
BackgroundMethodBatailler, C., Weidner, J., Wyatt, M., Pfluger, D., & Beck, M. (2019) · The Bone & Joint Journal · doi:10.1302/0301-620x.101b12.bjj-2019-0502.r1 · Cited by 37 · cited 2×
“In addition, we evaluated the breakdown in Shenton’s line, Cliff sign and femoro-epiphyseal acetabular roof (FEAR) index [2, 17, 20, 22, 23].”
BackgroundMethodIrie, T., Takahashi, D., Asano, T., et al. (2018) · Clinical Orthopaedics and Related Research · doi:10.1097/01.blo.0000533619.50951.e3 · Cited by 32
Hip microinstability diagnosis and management: a systematic review
Cohen, D., Jean, P.-O., Patel, M., et al. (2022) · Knee Surgery Sports Traumatology Arthroscopy · doi:10.1007/s00167-022-06976-7 · Cited by 32
Ishimaru, M., Shiraishi, Y., Ikebe, S., Higaki, H., Hino, K., Onishi, Y., & Miura, H. (2014) · Journal of Orthopaedic Research · doi:10.1002/jor.22596 · Cited by 30 · cited 2×
“Finally, the degree of femoral head translation during weight-bearing was small compared with the measurement accuracy of our computational 2D/3D image registration method (root mean square error of 0.2 mm in translation and 0.2° in rotation in porcine patellar bones [11]).”
MethodResultInfluentialDumont, G. D. (2016) · Clinics in Sports Medicine · doi:10.1016/j.csm.2016.02.008 · Cited by 29
Dynamic femoral head translations in dysplastic hips
Sato, T., Tanino, H., Nishida, Y., Ito, H., Matsuno, T., & Banks, S. A. (2017) · Clinical Biomechanics · doi:10.1016/j.clinbiomech.2017.05.003 · Cited by 28 · cited 3×
“In this study, the femoral head translation during weight-bearing in DDH ranged from 0.5 to 2.3 mm, similar values to those reported in previous studies on dynamic instability of definite DDH [1, 18].”
BackgroundResultInfluentialEvaluation of atraumatic hip instability measured by triaxial accelerometry during walking
Neira, A., Amenabar, T., Cristi-Sánchez, I., Rafols, C., Monckeberg, J. E., Belemmi, M., Neira, M., Soldan, M., & Silvestre, R. (2019) · Journal of Hip Preservation Surgery · doi:10.1093/jhps/hnz018 · Cited by 4 · cited 1×
“Dynamic instability of the hip joint is characterized by excessive femoral head translation within the acetabulum [16], which is determined by the bone morphology and integrity and laxity of surrounding soft tissues, including the labrum, capsular-ligamentous complex, and ligamentous teres.”
Background
Flagged first, then by citations
Research works printed but not linked: 1
- 10.1016/j.ostr.2016.09.002 · DOI
Cited by
Sorted by citations
Karisch, Q., Haertlé, M., Stamp, J., Ramadanov, N., Windhagen, H. J., & Ahmad, S. S. (2025) · Journal of Experimental Orthopaedics · doi:10.1002/jeo2.70407 · Cited by 12
Ramadanov, N., Voss, M., Heinz, M., et al. (2025) · Journal of Experimental Orthopaedics · doi:10.1002/jeo2.70453 · Cited by 7
Kitamura, K., Fujii, M., Motomura, G., Hamai, S., Kawahara, S., Sato, T., Yamaguchi, R., Hara, D., Utsunomiya, T., & Nakashima, Y. (2024) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.23.01132 · Cited by 6
Leopold, V. J., Rakhra, K. S., Spiker, A. M., Nepple, J. J., Beck, M., Karimijashni, M., Poitras, S., Beaulé, P. E., & Grammatopoulos, G. A. (2026) · Clinical Orthopaedics and Related Research · doi:10.1097/corr.0000000000003905 · Cited by 4
Gaddis, J. M., Arellano, E., Martin, B. C., Alsabawi, Y., Salgado‐Flores, M., South, C. C., Castañeda, P. G., & Wells, J. E. (2025) · Journal of Experimental Orthopaedics · doi:10.1002/jeo2.70457 · Cited by 3
“More speci fi cally, its use is being studied in orthopaedic surgery for various tasks, including answering common questions related to speci fi c surgeries [15, 24, 28, 32, 39], aiding with diagnosis [18], and assisting with clinical documentation [5, 21].”
Rivas, D. J. L., Gassmann, J. M., Goetz, J. E., et al. (2025) · Journal of Hip Preservation Surgery · doi:10.1093/jhps/hnaf001 · Cited by 3
“For example, registering NWB CT-derived geometry to standing AP radiographs can facilitate measurement of FHC translation, as was done in a recent study that found FHC translation from supine to standing in borderline (18 ∘ ≤ LCEA 25 ∘ ) dysplastic hips was on average 2.2 mm [54].”
InfluentialAssociation Between Hip Translation and Hip Rotation and Anatomy: A Pilot Quasi-static MRI Study
Kiapour, A. M., Mitchell, C., Hosseinzadeh, S., et al. (2024) · Orthopaedic Journal of Sports Medicine · doi:10.1177/23259671241275662 · Cited by 3
“…femoral head translations during rotation are in general agreement with those reported in previous studies of asymptomatic 1,10,19,23,30,38 and pathologic 1,9,15,20,23,24,31 hips, with the exception of smaller lateral translations seen in this in vivo study compared with a cadaveric study.”
BackgroundResultLocks, R., Guadagnin, E. C., Adam, G. P., et al. (2025) · Journal of Experimental Orthopaedics · doi:10.1002/jeo2.70215 · Cited by 2
Meza, A. D. V., Nocek, M. J., Felan, N. A., et al. (2025) · Open Access Journal of Sports Medicine · doi:10.2147/oajsm.s505874 · Cited by 2
“22 Contact-pressure mapping and computational modelling demonstrate systematic shifts in contact location and peak pressures with changes in flexion and rotation (cadaveric mean pressures commonly reported 1.5–4.4 MPa), indicating that modest translations and altered rotational restraint can…”
InfluentialFischer, M., Nonnenmacher, L., Nitsch, A., et al. (2025) · Knee Surgery Sports Traumatology Arthroscopy · doi:10.1002/ksa.12587 · Cited by 2
“Starting with the increased understanding of femor-oacetabular dynamics during weightbearing, the considerations of hip biomechanics have extended to the lumbo – pelvic – femoral axis [16, 30].”
Amagami, A., Sugiyama, H., & Saito, M. (2025) · Bone & Joint Open · doi:10.1302/2633-1462.64.bjo-2024-0276.r1 · Cited by 2
“Sakai et al 34 conducted a 3D measurement of femoral head displacement during weight-bearing in patients before PAO surgery and demonstrated that patients with BD (18° ≤ LCEA 25°) had significantly less displacement compared to patients with definite DDH (LCEA 18°), hypothesizing that…”
Kitamura, K., Fujii, M., Hamai, S., et al. (2025) · Orthopaedic Journal of Sports Medicine · doi:10.1177/23259671251319994 · Cited by 1
Rising star editorial: Periacetabular osteotomy—Reliable outcome and expanding indications
Pichler, L., & Ahmad, S. S. (2025) · Journal of Experimental Orthopaedics · doi:10.1002/jeo2.70499 · Cited by 1
“Alongside these expanded indications, patient selection criteria and surgical techniques have evolved [7, 19, 29, 37].”
Nithin, S., & Kanagaraj, S. (2025) · Journal of Orthopaedics · doi:10.1016/j.jor.2025.12.016 · Cited by 1
Triple‐Osteotomy leads to substantially improved quality of life in patients with hip dysplasia
Lenz, J. E., Riedl, M., Szymski, D., et al. (2025) · Journal of Experimental Orthopaedics · doi:10.1002/jeo2.70208
“Hip dysplasia is characterised by insuf fi cient development of the hip joint, resulting in reduced coverage of the acetabulum, lateralisation of the femoral head, instability, and consecutive damage to labrum and cartilage [6, 8, 15].”
The rise of hip research in the Journal of Experimental Orthopedics
Ahmad, S. S. (2025) · Journal of Experimental Orthopaedics · doi:10.1002/jeo2.70233
Metadata
- Authors
- Sakai, S., Kutsuna, T., Kono, K., Kinoshita, T., Mashima, N., & Takao, M.
- Affiliations
- Department of Bone and Joint Surgery Graduate School of Medicine Shitsukawa Ehime University Ehime 791‐0295 Toon City Japan
- Ehime University (JP)
- Corresponding author
- Takao, Masaki
- Venue
- Journal of Experimental Orthopaedics
- Publisher
- Wiley
- Published
- 2023-01
- Volume
- 10
- Issue
- 1
- Pages
- 126-126
- ISSN
- 2197-1153 (ISSN-L)
- PMC
- PMC10686934
- OpenAlex
- W4389147027
- Semantic Scholar
- 6ec98e1348d21d366b4a7b83c7522175e328fafc
- Cited by
- 16
- References
- 22
- Citations by year
- 2026: 1 · 2025: 13 · 2024: 2
- FWCI
- 3.86
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Journal of Experimental Orthopaedics (publishedVersion, cc-by)
- PubMed (publishedVersion)
- PubMed Central (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Japan Society for the Promotion of Science London (JP18K09104, JP19H01176)
- Topics
- Health Sciences › Medicine › Surgery › Hip disorders and treatments
- Physical Sciences › Engineering › Biomedical Engineering › Lower Extremity Biomechanics and Pathologies
- Health Sciences › Medicine › Surgery › Orthopaedic implants and arthroplasty
- Keywords
- developmental dysplasia of the hip, weight bearing, center-edge angle, 2D-3D registration, periacetabular osteotomy, hip stability
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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